Reference on EC 1.4.3.4 - monoamine oxidase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schilling, B.; Lerch, K.
Amine oxidases from Aspergillus niger: identification of a novel flavin-dependent enzyme
Biochim. Biophys. Acta
1243
529-537
1995
Aspergillus niger
Manually annotated by BRENDA team
Erwin, V.G.; Hellerman, L.
Mitochondrial monoamine oxidase. I. Purification and characterization of the bovine kidney enzyme
J. Biol. Chem.
242
4230-4238
1967
Bos taurus
Manually annotated by BRENDA team
Tipton, K.F.
The prosthetic groups of pig brain mitochondrial monoamine oxidase
Biochim. Biophys. Acta
159
451-459
1968
Sus scrofa
Manually annotated by BRENDA team
Powell, J.F.
Molecular biological studies of monoamine oxidase: structure and function
Biochem. Soc. Trans.
19
199-201
1991
Homo sapiens
Manually annotated by BRENDA team
Newton-Vinson, P.; Hubalek, F.; Edmondson, D.E.
High-level expression of human liver monoamine oxidase B in Pichia pastoris
Protein Expr. Purif.
20
334-345
2000
Bos taurus, Homo sapiens
Manually annotated by BRENDA team
Li, M.; Hubalek, F.; Newton-Vinson, P.; Edmondson, D.E.
High-level expression of human liver monoamine oxidase A in Pichia pastoris: comparison with the enzyme expressed in Saccharomyces cerevisiae
Protein Expr. Purif.
24
152-162
2002
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Nandigama, R.K.; Miller, J.R.; Edmondson, D.E.
Loss of serotonin oxidation as a component of the altered substrate specificity in the Y444F mutant of recombinant human liver MAO A
Biochemistry
40
14839-14846
2001
Homo sapiens
Manually annotated by BRENDA team
Balsa, D.; Fernandez-Alverez, E.; Tipton, K.F.; Unzeta, M.
Monoamine oxidase inhibitory potencies and selectivities of 2-[N-(2-propynyl)-aminomethyl]-1-methyl indole derivatives
Biochem. Soc. Trans.
19
215-218
1991
Rattus norvegicus
Manually annotated by BRENDA team
Ramsay, R.R.; Singer, T.P.
The kinetic mechanisms of monoamine oxidases A and B
Biochem. Soc. Trans.
19
219-223
1991
Bos taurus, Homo sapiens
Manually annotated by BRENDA team
Ma, J.; Ito, A.
Tyrosine residues near the FAD binding site are critical for FAD binding and for the maintenance of the stable and active conformation of rat monoamine oxidase A
J. Biochem.
131
107-111
2002
Rattus norvegicus, Rattus norvegicus MAO-A
Manually annotated by BRENDA team
Oreland, L.
Purification and properties of pig liver mitochondrial monoamine oxidase
Arch. Biochem. Biophys.
146
410-412
1971
Sus scrofa
Manually annotated by BRENDA team
Veryovkina, L.V.; Samed, M.M.A.; Gorkin, V.Z.
Mitochondrial monoamine oxidase of rat liver: reversible qualitative alterations in catalytic properties
Biochim. Biophys. Acta
258
56-70
1972
Rattus norvegicus
Manually annotated by BRENDA team
Tipton, K.F.; Spires, I.P.C.
The kinetics of phenethylhydrazine oxidation by monoamine oxidase
Biochem. J.
125
521-524
1971
Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Tipton, M.F.; Houslay, M.D.; Garrett, N.J.
Rapid screening assay for revertants derived from MSV-transformed cells
Nature
246
213-214
1973
Homo sapiens
Manually annotated by BRENDA team
Suzuki, H.; Ogura, Y.; Yamada, H.
Kinetic studies on the amine oxidase reaction
J. Biochem.
72
703-712
1972
Aspergillus niger
Manually annotated by BRENDA team
Houslay, M.D.; Tipton, K.F.
A kinetic evaluation of monoamine oxidase activity in rat liver mitochondrial outer membranes
Biochem. J.
139
645-652
1974
Rattus norvegicus
Manually annotated by BRENDA team
Akopyan, Z.I.; Kulygina, A.A.; Terzeman, I.I.; Gorkin, V.Z.
Induced appearance of adenylate-deaminating activity in highly purified bovine liver mitochondrial monoamine oxidase
Biochim. Biophys. Acta
289
44-56
1972
Bos taurus
Manually annotated by BRENDA team
Norstrand, I.F.; Glantz, M.D.
Purification and properties of human liver monoamine oxidase
Arch. Biochem. Biophys.
158
1-11
1973
Homo sapiens
Manually annotated by BRENDA team
Dennick, R.G.; Mayer, R.J.
Purification and immunochemical characterization of monoamine oxidase from rat and human liver
Biochem. J.
161
167-174
1977
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Pearce, L.B.; Roth, J.A.
Human brain monoamine oxidase: solubilization and kinetics of inhibition by octylglucoside
Arch. Biochem. Biophys.
224
464-472
1983
Homo sapiens
Manually annotated by BRENDA team
Stadt, M.A.; Banks, P.A.; Kobes, R.D.
Purification of rat liver monoamine oxidase by octyl glucoside extraction and reconstitution
Arch. Biochem. Biophys.
214
223-230
1982
Rattus norvegicus
Manually annotated by BRENDA team
Weyler, W.; Salach, J.I.
Purification and properties of mitochondrial monoamine oxidase type A from human placenta
J. Biol. Chem.
260
13199-13207
1985
Homo sapiens
Manually annotated by BRENDA team
McCauley, R.
Properties of a monoamine oxidase from rat liver mitochondrial outer membranes
Arch. Biochem. Biophys.
189
8-13
1978
Rattus norvegicus
Manually annotated by BRENDA team
Inagaki, T.; Rao, N.A.; Yagi, K.
Modulation by phospholipids of the activity of monoamine oxidase purified from pig liver
J. Biochem.
100
597-603
1986
Sus scrofa
Manually annotated by BRENDA team
Pohl, B.; Schmidt, W.
Comparative studies of purified and reconstituted monoamine oxidase from bovine liver mitochondria
Biochim. Biophys. Acta
731
338-345
1983
Bos taurus
Manually annotated by BRENDA team
Balsa, M.D.; Gomez, N.; Unzeta, M.
Characterization of monoamine oxidase activity present in human granulocytes and lymphocytes
Biochim. Biophys. Acta
992
140-144
1989
Homo sapiens
Manually annotated by BRENDA team
Dugal, B.S.
Localization, purification and substrate specificity of monoamine oxidase
Biochim. Biophys. Acta
480
56-69
1977
Bos taurus
Manually annotated by BRENDA team
Youdim, M.B.H.; Tenne, M.
Assay and purification of liver monoamine oxidase
Methods Enzymol.
142
617-627
1987
Rattus norvegicus
Manually annotated by BRENDA team
Ramsay, R.R.
Kinetic mechanism of monoamine oxidase A
Biochemistry
30
4624-4629
1991
Homo sapiens
Manually annotated by BRENDA team
Husain, M.; Edmondson, D.E.; Singer, T.P.
Kinetic studies on the catalytic mechanism of liver monoamine oxidase
Biochemistry
21
595-600
1982
Bos taurus
Manually annotated by BRENDA team
Lindström, A.; Olsson, B.; Petterson, G.; Szymanska, J.
Kinetics of the interaction between pig-plasma benzylamine oxidase and various monoamines
Eur. J. Biochem.
47
99-105
1974
Sus scrofa
Manually annotated by BRENDA team
Weyler, W.; Salach, J.I.
Iron content and spectral properties of highly purified bovine liver monoamine oxidase
Arch. Biochem. Biophys.
212
147-153
1981
Bos taurus
Manually annotated by BRENDA team
Roth, J.A.; Eddy, B.J.
Kinetic properties of membrane-bound and Triton X-100-solubilized human brain monoamine oxidase
Arch. Biochem. Biophys.
205
260-266
1980
Homo sapiens
Manually annotated by BRENDA team
Salach, J.I.
Monoamine oxidase from beef liver mitochondria: simplified isolation procedure, properties, and determination of its cysteinyl flavin content
Arch. Biochem. Biophys.
192
128-137
1979
Bos taurus
Manually annotated by BRENDA team
Minamiura, N.; Yasunobu, K.T.
Bovine liver monoamine oxidase. A modified purification procedure and preliminary evidence for two subunits and one FAD
Arch. Biochem. Biophys.
189
481-489
1978
Bos taurus
Manually annotated by BRENDA team
Gottowik, J.; Cesura, A.M.; Malherbe, P.; Lang, G.; Da Prada, M.
Characterization of wild-type and mutant forms of human monoamine oxidase A and B expressed in a mammalian cell line
FEBS Lett.
317
152-156
1993
Homo sapiens
Manually annotated by BRENDA team
Kuttab, S.; Kalgutkar, A.; Castagnoli, N.Jr.
Mechanistic studies on the monoamine oxidase B catalyzed oxidation of 1,4-disubstituted tetrahydropyridines
Chem. Res. Toxicol.
7
740-744
1994
Bos taurus
Manually annotated by BRENDA team
Hirashiki, I.; Ogata, F.; Ito, A.
Rat monoamine oxidase B expressed in Escherichia coli has a covalently-bound FAD
Biochem. Mol. Biol. Int.
37
39-44
1995
Rattus norvegicus
Manually annotated by BRENDA team
Zhou, B.P.; Lewis, D.A.; Kwan, S.W.; Kirksey, T.J.; Abell, C.W.
Mutagenesis at a highly conserved tyrosine in monoamine oxidase B affects FAD incorporation and catalytic activity
Biochemistry
34
9526-9531
1995
Homo sapiens
Manually annotated by BRENDA team
Hiro, I.; Tsugeno, Y.; Hirashiki, I.; Ogata, F.; Ito, A.
Characterization of rat monoamine oxidase A with noncovalently-bound FAD expressed in yeast cells
J. Biochem.
120
759-765
1996
Rattus norvegicus
Manually annotated by BRENDA team
Sablin, S.O.; Ramsay, R.R.
Monoamine oxidase contains a redox-active disulfide
J. Biol. Chem.
273
14074-14076
1998
Homo sapiens
Manually annotated by BRENDA team
Ma, J.; Kubota, F.; Yoshimura, M.; Yamashita, E.; Nakagawa, A.; Ito, A.; Tsukihara, T.
Crystallization and preliminary crystallographic analysis of rat monoamine oxidase A complexed with clorgyline
Acta Crystallogr. Sect. D
60
317-319
2004
Rattus norvegicus
Manually annotated by BRENDA team
Herraiz, T.; Chaparro, C.
Human monoamine oxidase is inhibited by tobacco smoke: beta-carboline alkaloids act as potent and reversible inhibitors
Biochem. Biophys. Res. Commun.
326
378-386
2005
Homo sapiens
Manually annotated by BRENDA team
Ramsay, R.R.; Hunter, D.J.
Inhibitors alter the spectrum and redox properties of monoamine oxidase A
Biochim. Biophys. Acta
1601
178-184
2002
Homo sapiens
Manually annotated by BRENDA team
Nicotra, A.; Falasca, L.; Senatori, O.; Devirgiliis, L.C.
Monoamine oxidase A and B activities in embryonic chick hepatocytes: differential regulation by retinoic acid
Cell Biochem. Funct.
20
87-94
2002
Gallus gallus
Manually annotated by BRENDA team
Edmondson, D.E.; Mattevi, A.; Binda, C.; Li, M.; Hubalek, F.
Structure and mechanism of monoamine oxidase
Curr. Med. Chem.
11
1983-1993
2004
Homo sapiens
Manually annotated by BRENDA team
Ucar, G.
Substrate specificities of monoamine oxidase isoforms
FABAD J. Pharm. Sci.
27
149-156
2002
Homo sapiens, Rattus norvegicus
-
Manually annotated by BRENDA team
Binda, C.; Hubalek, F.; Li, M.; Edmondson, D.E.; Mattevi, A.
Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane
FEBS Lett.
564
225-228
2004
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Ramonet, D.; Rodriguez, M.; Saura, J.; Lizcano, J.M.; Romera, M.; Unzeta, M.; Finch, C.; Billett, E.; Mahy, N.
Localization of monoamine oxidase A and B and semicarbazide-sensitive amine oxidase in human peripheral tissues
Inflammopharmacology
11
111-117
2003
Homo sapiens
Manually annotated by BRENDA team
Lee, Y.; Ling, K.Q.; Lu, X.; Silverman, R.B.; Shepard, E.M.; Dooley, D.M.; Sayre, L.M.
3-Pyrrolines are mechanism-based inactivators of the quinone-dependent amine oxidases but only substrates of the flavin-dependent amine oxidases
J. Am. Chem. Soc.
124
12135-12143
2002
Bos taurus, Bos taurus (P56560)
Manually annotated by BRENDA team
Geha, R.M.; Chen, K.; Wouters, J.; Ooms, F.; Shih, J.C.
Analysis of conserved active site residues in monoamine oxidase A and B and their three-dimensional molecular modeling
J. Biol. Chem.
277
17209-17216
2002
Homo sapiens
Manually annotated by BRENDA team
Markoglou, N.; Hsuesh, R.; Wainer, I.W.
Immobilized enzyme reactors based upon the flavoenzymes monoamine oxidase A and B
J. Chromatogr. B
804
295-302
2004
Homo sapiens
Manually annotated by BRENDA team
Binda, C.; Hubalek, F.; Li, M.; Herzig, Y.; Sterling, J.; Edmondson, D.E.; Mattevi, A.
Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class
J. Med. Chem.
47
1767-1774
2004
Homo sapiens (P27338)
Manually annotated by BRENDA team
Ma, J.; Yoshimura, M.; Yamashita, E.; Nakagawa, A.; Ito, A.; Tsukihara, T.
Structure of rat monoamine oxidase A and its specific recognitions for substrates and inhibitors
J. Mol. Biol.
338
103-114
2004
Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Egashira, T.; Takayama, F.; Sakai, K.
Inhibition by Zn2+ of A-form monoamine oxidase in monkey brain mitochondria
J. Pharm. Sci.
91
239-245
2003
Macaca fuscata, Oryctolagus cuniculus, Rattus norvegicus
Manually annotated by BRENDA team
Guimaraes, J.T.; Vindis, C.; Soares-da-Silva, P.; Parini, A.
Differential substrate specificity of monoamine oxidase in the rat heart and renal cortex
Life Sci.
73
955-967
2003
Rattus norvegicus
Manually annotated by BRENDA team
Binda, C.; Newton-Vinson, P.; Hubalek, F.; Edmondson, D.E.; Mattevi, A.
Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders
Nat. Struct. Biol.
9
22-26
2002
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Nakagawasai, O.; Arai, Y.; Satoh, S.e.; Satoh, N.; Neda, M.; Hozumi, M.; Oka, R.; Hiraga, H.; Tadano, T.
Monoamine oxidase and head-twitch response in mice. Mechanisms of alpha-methylated substrate derivatives
Neurotoxicology
25
223-232
2004
Mus musculus
Manually annotated by BRENDA team
Dittmann, K.; Riese, U.; Hamburger, M.
HPLC-based bioactivity profiling of plant extracts: a kinetic assay for the identification of monoamine oxidase-A inhibitors using human recombinant monoamine oxidase-A
Phytochemistry
65
2885-2891
2004
Homo sapiens
Manually annotated by BRENDA team
Binda, C.; Li, M.; Hubalek, F.; Restelli, N.; Edmondson, D.E.; Mattevi, A.
Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures
Proc. Natl. Acad. Sci. USA
100
9750-9755
2003
Homo sapiens
Manually annotated by BRENDA team
Ucar, G.; Tas, C.; Tuemer, A.
Monoamine oxidase inhibitory activities of the scorpion Mesobuthus gibbosus (Buthidae) venom peptides
Toxicon
45
43-52
2005
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Petrovic, N.; Cvijic, G.; Djordjevic, J.; Davidovic, V.
The activities of antioxidant enzymes and monoamine oxidase and uncoupling protein 1 content in brown fat of hypo- and hyperthyroid rats
Ann. N. Y. Acad. Sci.
1040
431-435
2005
Rattus norvegicus
Manually annotated by BRENDA team
Jones, T.Z.; Fleming, P.; Eyermann, C.J.; Gravestock, M.B.; Ramsay, R.R.
Orientation of oxazolidinones in the active site of monoamine oxidase
Biochem. Pharmacol.
70
407-416
2005
Homo sapiens (P21397)
Manually annotated by BRENDA team
Li, M.; Binda, C.; Mattevi, A.; Edmondson, D.E.
Functional role of the 'aromatic cage' in human monoamine oxidase B: structures and catalytic properties of Tyr435 mutant proteins
Biochemistry
45
4775-4784
2006
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Ochiai, Y.; Itoh, K.; Sakurai, E.; Adachi, M.; Tanaka, Y.
Substrate selectivity of monoamine oxidase A, monoamine oxidase B, diamine oxidase, and semicarbazide-sensitive amine oxidase in COS-1 expression systems
Biol. Pharm. Bull.
29
2362-2366
2006
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Vintem, A.P.; Price, N.T.; Silverman, R.B.; Ramsay, R.R.
Mutation of surface cysteine 374 to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines
Bioorg. Med. Chem.
13
3487-3495
2005
Homo sapiens (P21397)
Manually annotated by BRENDA team
Tao, G.; Irie, Y.; Li, D.J.; Keung, W.M.
Eugenol and its structural analogs inhibit monoamine oxidase A and exhibit antidepressant-like activity
Bioorg. Med. Chem.
13
4777-4788
2005
Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Rimoldi, J.M.; Puppali, S.G.; Isin, E.; Bissel, P.; Khalil, A.; Castagnoli, N.
A novel and selective monoamine oxidase B substrate
Bioorg. Med. Chem.
13
5808-5813
2005
Homo sapiens (P21397), Papio hamadryas
Manually annotated by BRENDA team
Novaroli, L.; Reist, M.; Favre, E.; Carotti, A.; Catto, M.; Carrupt, P.A.
Human recombinant monoamine oxidase B as reliable and efficient enzyme source for inhibitor screening
Bioorg. Med. Chem.
13
6212-6217
2005
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Vlok, N.; Malan, S.F.; Castagnoli, N.; Bergh, J.J.; Petzer, J.P.
Inhibition of monoamine oxidase B by analogues of the adenosine A2A receptor antagonist (E)-8-(3-chlorostyryl)caffeine (CSC)
Bioorg. Med. Chem.
14
3512-3521
2006
Papio hamadryas
Manually annotated by BRENDA team
Toprakci, M.; Yelekci, K.
Docking studies on monoamine oxidase-B inhibitors: estimation of inhibition constants (K(i)) of a series of experimentally tested compounds
Bioorg. Med. Chem. Lett.
15
4438-4446
2005
Homo sapiens (P27338)
Manually annotated by BRENDA team
Chimenti, F.; Secci, D.; Bolasco, A.; Chimenti, P.; Granese, A.; Carradori, S.; Befani, O.; Turini, P.; Alcaro, S.; Ortuso, F.
Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of N,N-bis[2-oxo-2H-benzopyran]-3-carboxamides
Bioorg. Med. Chem. Lett.
16
4135-4140
2006
Bos taurus (P21398), Bos taurus (P56560), Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Chimenti, F.; Bolasco, A.; Manna, F.; Secci, D.; Chimenti, P.; Granese, A.; Befani, O.; Turini, P.; Cirilli, R.; La Torre, F.; Alcaro, S.; Ortuso, F.; Langer, T.
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors
Curr. Med. Chem.
13
1411-1428
2006
Bos taurus (P21398), Bos taurus (P56560)
Manually annotated by BRENDA team
Hubalek, F.; Binda, C.; Khalil, A.; Li, M.; Mattevi, A.; Castagnoli, N.; Edmondson, D.E.
Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors
J. Biol. Chem.
280
15761-15766
2005
Bos taurus, Bos taurus (P56560), Equus caballus, Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338), Mus musculus, Mus musculus (Q8BW75), Ovis aries, Rattus norvegicus (P19643)
Manually annotated by BRENDA team
Ou, X.M.; Chen, K.; Shih, J.C.
Glucocorticoid and androgen activation of monoamine oxidase A is regulated differently by R1 and Sp1
J. Biol. Chem.
281
21512-21525
2006
Homo sapiens
Manually annotated by BRENDA team
Anichtchik, O.; Sallinen, V.; Peitsaro, N.; Panula, P.
Distinct structure and activity of monoamine oxidase in the brain of zebrafish (Danio rerio)
J. Comp. Neurol.
498
593-610
2006
Danio rerio, Danio rerio (Q6NSN2)
Manually annotated by BRENDA team
Dar, A.; Khan, K.M.; Ateeq, H.S.; Khan, S.; Rahat, S.; Perveen, S.; Supuran, C.T.
Inhibition of monoamine oxidase-A activity in rat brain by synthetic hydrazines: structure-activity relationship (SAR)
J. Enzyme Inhib. Med. Chem.
20
269-274
2005
Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Huh, J.W.; Choi, M.M.; Lee, J.H.; Yang, S.J.; Kim, M.J.; Choi, J.; Lee, K.H.; Lee, J.E.; Cho, S.W.
Activation of monoamine oxidase isotypes by prolonged intake of aluminum in rat brain
J. Inorg. Biochem.
99
2088-2091
2005
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Bertini, V.; Buffoni, F.; Ignesti, G.; Picci, N.; Trombino, S.; Iemma, F.; Alfei, S.; Pocci, M.; Lucchesini, F.; De Munno, A.
Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases
J. Med. Chem.
48
664-670
2005
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Chimenti, F.; Maccioni, E.; Secci, D.; Bolasco, A.; Chimenti, P.; Granese, A.; Befani, O.; Turini, P.; Alcaro, S.; Ortuso, F.; Cirilli, R.; La Torre, F.; Cardia, M.C.; Distinto, S.
Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazole derivatives
J. Med. Chem.
48
7113-7122
2005
Bos taurus (P21398), Bos taurus (P56560)
Manually annotated by BRENDA team
Catto, M.; Nicolotti, O.; Leonetti, F.; Carotti, A.; Favia, A.D.; Soto-Otero, R.; Mendez-Alvarez, E.; Carotti, A.
Structural insights into monoamine oxidase inhibitory potency and selectivity of 7-substituted coumarins from ligand- and target-based approaches
J. Med. Chem.
49
4912-4925
2006
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Herraiz, T.; Chaparro, C.
Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee
Life Sci.
78
795-802
2006
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Carpene, C.; Daviaud, D.; Boucher, J.; Bour, S.; Visentin, V.; Gres, S.; Duffaut, C.; Fontana, E.; Testar, X.; Saulnier-Blache, J.S.; Valet, P.
Short- and long-term insulin-like effects of monoamine oxidases and semicarbazide-sensitive amine oxidase substrates in cultured adipocytes
Metab. Clin. Exp.
55
1397-1405
2006
Mus musculus
Manually annotated by BRENDA team
Lewitzka, U.; Mueller-Oerlinghausen, B.; Felber, W.; Brunner, J.; Hawellek, B.; Rujescu, D.; Ising, M.; Lauterbach, E.; Broocks, A.; Bondy, B.; Rao, M.L.; Frahnert, C.; Heuser, I.; Hohagen, F.; Maier, W.; Bronisch, T.
Is MAO-B activity in platelets associated with the occurrence of suicidality and behavioural personality traits in depressed patients?
Acta Psychiatr. Scand.
117
41-49
2008
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Nilsson, K.W.; Sjoeberg, R.L.; Wargelius, H.L.; Leppert, J.; Lindstroem, L.; Oreland, L.
The monoamine oxidase A (MAO-A) gene, family function and maltreatment as predictors of destructive behaviour during male adolescent alcohol consumption
Addiction
102
389-398
2007
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Bortolato, M.; Chen, K.; Shih, J.C.
Monoamine oxidase inactivation: From pathophysiology to therapeutics
Adv. Drug Deliv. Rev.
60
1527-1533
2008
Homo sapiens (P21397), Homo sapiens (P27338), Mus musculus (Q64133)
Manually annotated by BRENDA team
Vishnivetskaya, G.B.; Skrinskaya, J.A.; Seif, I.; Popova, N.K.
Effect of MAO A deficiency on different kinds of aggression and social investigation in mice
Aggress. Behav.
33
1-6
2007
Mus musculus, Mus musculus (Q64133)
Manually annotated by BRENDA team
Berggren, U.; Eriksson, M.; Fahlke, C.; Blennow, K.; Balldin, J.
Different effects of smoking or use of smokeless tobacco on platelet MAO-B activity in type 1 alcohol-dependent subjects
Alcohol Alcohol.
42
267-271
2007
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Pombo, S.; Levy, P.; Bicho, M.; Ismail, F.; Cardoso, J.M.
Neuropsychological function and platelet monoamine oxidase activity levels in type I alcoholic patients
Alcohol Alcohol.
43
423-430
2008
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Rodriguez-Revenga, L.; Madrigal, I.; Alkhalidi, L.S.; Armengol, L.; Gonzalez, E.; Badenas, C.; Estivill, X.; Mila, M.
Contiguous deletion of the NDP, MAOA, MAOB, and EFHC2 genes in a patient with Norrie disease, severe psychomotor retardation and myoclonic epilepsy
Am. J. Med. Genet. A
143A
916-920
2007
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Li, J.; Kang, C.; Zhang, H.; Wang, Y.; Zhou, R.; Wang, B.; Guan, L.; Yang, L.; Faraone, S.V.
Monoamine oxidase A gene polymorphism predicts adolescent outcome of attention-deficit/hyperactivity disorder
Am. J. Med. Genet. B Neuropsychiatr. Genet.
144B
430-433
2007
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Li, J.; Wang, Y.; Hu, S.; Zhou, R.; Yu, X.; Wang, B.; Guan, L.; Yang, L.; Zhang, F.; Faraone, S.V.
The monoamine oxidase B gene exhibits significant association to ADHD
Am. J. Med. Genet. B Neuropsychiatr. Genet.
147
370-374
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Li, D.; He, L.
Meta-study on association between the monoamine oxidase A gene (MAOA) and schizophrenia
Am. J. Med. Genet. B Neuropsychiatr. Genet.
147B
174-178
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Prichard, Z.; Mackinnon, A.; Jorm, A.F.; Easteal, S.
No evidence for interaction between MAOA and childhood adversity for antisocial behavior
Am. J. Med. Genet. B Neuropsychiatr. Genet.
147B
228-232
2008
Homo sapiens (P21397)
Manually annotated by BRENDA team
Philibert, R.A.; Gunter, T.D.; Beach, S.R.; Brody, G.H.; Madan, A.
MAOA methylation is associated with nicotine and alcohol dependence in women
Am. J. Med. Genet. B Neuropsychiatr. Genet.
147B
565-570
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Gao, X.; Scott, W.K.; Wang, G.; Mayhew, G.; Li, Y.J.; Vance, J.M.; Martin, E.R.
Gene-gene interaction between FGF20 and MAOB in Parkinson disease
Ann. Hum. Genet.
72
157-162
2008
Homo sapiens (P27338)
Manually annotated by BRENDA team
Palaska, E.; Aydin, F.; Ucar, G.; Erol, D.
Synthesis and monoamine oxidase inhibitory activities of 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-1H-pyrazole derivatives
Arch. Pharm.
341
209-215
2008
Homo sapiens, Homo sapiens (P27338), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Lin, Y.M.; Davamani, F.; Yang, W.C.; Lai, T.J.; Sun, H.S.
Association analysis of monoamine oxidase A gene and bipolar affective disorder in Han Chinese
Behav. Brain Funct.
4
21
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Harkcom, W.T.; Bevan, D.R.
Molecular docking of inhibitors into monoamine oxidase B
Biochem. Biophys. Res. Commun.
360
401-406
2007
Homo sapiens (P27338)
Manually annotated by BRENDA team
Upadhyay, A.K.; Wang, J.; Edmondson, D.E.
Comparison of the structural properties of the active site cavities of human and rat monoamine oxidase A and B in their soluble and membrane-bound forms
Biochemistry
47
526-536
2008
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338), Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Bour, S.; Daviaud, D.; Gres, S.; Lefort, C.; Prevot, D.; Zorzano, A.; Wabitsch, M.; Saulnier-Blache, J.S.; Valet, P.; Carpene, C.
Adipogenesis-related increase of semicarbazide-sensitive amine oxidase and monoamine oxidase in human adipocytes
Biochimie
89
916-925
2007
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Kumar, P.; Taha, A.; Sharma, D.; Kale, R.K.; Baquer, N.Z.
Effect of dehydroepiandrosterone (DHEA) on monoamine oxidase activity, lipid peroxidation and lipofuscin accumulation in aging rat brain regions
Biogerontology
9
235-246
2008
Rattus norvegicus
Manually annotated by BRENDA team
Guillem, K.; Vouillac, C.; Koob, G.F.; Cador, M.; Stinus, L.
Monoamine oxidase inhibition dramatically prolongs the duration of nicotine withdrawal-induced place aversion
Biol. Psychiatry
63
158-163
2008
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Brummett, B.H.; Boyle, S.H.; Siegler, I.C.; Kuhn, C.M.; Surwit, R.S.; Garrett, M.E.; Collins, A.; Ashley-Koch, A.; Williams, R.B.
HPA axis function in male caregivers: Effect of the monoamine oxidase-A gene promoter (MAOA-uVNTR)
Biol. Psychol.
79
250-255
2008
Homo sapiens (P21397)
Manually annotated by BRENDA team
van den Berg, D.; Zoellner, K.R.; Ogunrombi, M.O.; Malan, S.F.; TerreBlanche, G.; Castagnoli, N.; Bergh, J.J.; Petzer, J.P.
Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues
Bioorg. Med. Chem.
15
3692-3702
2007
Papio hamadryas
Manually annotated by BRENDA team
Gökhan-Kelekci, N.; Yabanoglu, S.; Küepeli, E.; Salgin, U.; Özgen, O.; Ucar, G.; Ye?ilada, E.; Kendi, E.; Yesilada, A.; Bilgin, A.A.
A new therapeutic approach in Alzheimer disease: some novel pyrazole derivatives as dual MAO-B inhibitors and antiinflammatory analgesics
Bioorg. Med. Chem.
15
5775-5786
2007
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Ogunrombi, M.O.; Malan, S.F.; Terreblanche, G.; Castagnoli, N.; Bergh, J.J.; Petzer, J.P.
Structure-activity relationships in the inhibition of monoamine oxidase B by 1-methyl-3-phenylpyrroles
Bioorg. Med. Chem.
16
2463-2472
2008
Papio hamadryas
Manually annotated by BRENDA team
Bissel, P.; Khalil, A.; Rimoldi, J.M.; Igarashi, K.; Edmondson, D.; Miller, A.; Castagnoli, N.
Stereochemical studies on the novel monoamine oxidase B substrates (1R,6S)- and (1S,6R)-3-methyl-6-phenyl-3-aza-bicyclo[4.1.0]heptane
Bioorg. Med. Chem.
16
3557-3564
2008
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Ke, S.; Li, Z.; Qian, X.
1,3,4-Oxadiazole-3(2H)-carboxamide derivatives as potential novel class of monoamine oxidase (MAO) inhibitors: synthesis, evaluation, and role of urea moiety
Bioorg. Med. Chem.
16
7565-7572
2008
Rattus norvegicus
Manually annotated by BRENDA team
Xu, X.; Brookes, K.; Chen, C.; Huang, Y.; Wu, Y.; Asherson, P.
Association study between the monoamine oxidase A gene and attention deficit hyperactivity disorder in Taiwanese samples
BMC Psychiatry
7
10
2007
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Malmberg, K.; Wargelius, H.L.; Lichtenstein, P.; Oreland, L.; Larsson, J.O.
ADHD and disruptive behavior scores - associations with MAO-A and 5-HTT genes and with platelet MAO-B activity in adolescents
BMC Psychiatry
8
28
2008
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Wu, Y.H.; Fischer, D.F.; Swaab, D.F.
A promoter polymorphism in the monoamine oxidase A gene is associated with the pineal MAOA activity in Alzheimers disease patients
Brain Res.
1167
13-19
2007
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Aguiar, L.M.; Macedo, D.S.; Vasconcelos, S.M.; Oliveira, A.A.; de Sousa, F.C.; Viana, G.S.
CSC, an adenosine A(2A) receptor antagonist and MAO B inhibitor, reverses behavior, monoamine neurotransmission, and amino acid alterations in the 6-OHDA-lesioned rats
Brain Res.
1191
192-199
2008
Rattus norvegicus (P19643), Rattus norvegicus, Rattus norvegicus Wistar (P19643)
Manually annotated by BRENDA team
Cerasa, A.; Gioia, M.C.; Fera, F.; Passamonti, L.; Liguori, M.; Lanza, P.; Muglia, M.; Magariello, A.; Quattrone, A.
Ventro-lateral prefrontal activity during working memory is modulated by MAO A genetic variation
Brain Res.
1201
114-121
2008
Homo sapiens (P21397)
Manually annotated by BRENDA team
Birgner, C.; Kindlundh-Hoegberg, A.M.; Oreland, L.; Alsioe, J.; Lindblom, J.; Schioeth, H.B.; Bergstroem, L.
Reduced activity of monoamine oxidase in the rat brain following repeated nandrolone decanoate administration
Brain Res.
1219
103-110
2008
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Bailey, K.R.; Ellis, A.J.; Reiss, R.; Snape, T.J.; Turner, N.J.
A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (+/-)-crispine A
Chem. Commun. (Camb. )
2007
3640-3642
2007
Aspergillus niger, Aspergillus niger (P46882)
Manually annotated by BRENDA team
Hewton, R.; Salem, A.; Irvine, R.J.
Potentiation of 3,4-methylenedioxymethamphetamine-induced 5-HT release in the rat substantia nigra by clorgyline, a monoamine oxidase A inhibitor
Clin. Exp. Pharmacol. Physiol.
34
1051-1057
2007
Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Chen, J.J.; Swope, D.M.; Dashtipour, K.
Comprehensive review of rasagiline, a second-generation monoamine oxidase inhibitor, for the treatment of Parkinsons disease
Clin. Ther.
29
1825-1849
2007
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Hampp, G.; Ripperger, J.A.; Houben, T.; Schmutz, I.; Blex, C.; Perreau-Lenz, S.; Brunk, I.; Spanagel, R.; Ahnert-Hilger, G.; Meijer, J.H.; Albrecht, U.
Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood
Curr. Biol.
18
678-683
2008
Mus musculus, Mus musculus (Q64133)
Manually annotated by BRENDA team
Dunkel, P.; Gelain, A.; Barlocco, D.; Haider, N.; Gyires, K.; Sperlagh, B.; Magyar, K.; Maccioni, E.; Fadda, A.; Matyus, P.
Semicarbazide-sensitive amine oxidase/vascular adhesion protein 1: recent developments concerning substrates and inhibitors of a promising therapeutic target
Curr. Med. Chem.
15
1827-1839
2008
Homo sapiens (P21397), Homo sapiens (P27338), Rattus norvegicus
Manually annotated by BRENDA team
Zhao, H.; Nolley, R.; Chen, Z.; Reese, S.W.; Peehl, D.M.
Inhibition of monoamine oxidase A promotes secretory differentiation in basal prostatic epithelial cells
Differentiation
76
820-830
2008
Homo sapiens (P21397)
Manually annotated by BRENDA team
Nilsson, K.W.; Wargelius, H.L.; Sjoeberg, R.L.; Leppert, J.; Oreland, L.
The MAO-A gene, platelet MAO-B activity and psychosocial environment in adolescent female alcohol-related problem behaviour
Drug Alcohol Depend.
93
51-62
2008
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Huang, S.Y.; Lin, M.T.; Shy, M.J.; Lin, W.W.; Lin, F.Y.; Lu, R.B.
Neither single-marker nor haplotype analyses support an association between monoamine oxidase A gene and bipolar disorder
Eur. Arch. Psychiatry Clin. Neurosci.
258
350-356
2008
Homo sapiens (P21397)
Manually annotated by BRENDA team
De Luca, V.; Tharmaligam, S.; Strauss, J.; Kennedy, J.L.
5-ht2c receptor and mao-a interaction analysis: no association with suicidal behaviour in bipolar patients
Eur. Arch. Psychiatry Clin. Neurosci.
258
428-433
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Chimenti, F.; Fioravanti, R.; Bolasco, A.; Manna, F.; Chimenti, P.; Secci, D.; Rossi, F.; Turini, P.; Ortuso, F.; Alcaro, S.; Cardia, M.C.
Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives
Eur. J. Med. Chem.
43
2262-2267
2008
Bos taurus (P21398), Bos taurus (P56560)
Manually annotated by BRENDA team
Reif, A.; Scarpini, E.; Venturelli, E.; Toepner, T.; Fenoglio, C.; Lesch, K.P.; Galimberti, D.
The functional MAOA-uVNTR promoter polymorphism in patients with frontotemporal dementia
Eur. J. Neurol.
15
637-639
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Izumi, T.; Iwamoto, N.; Kitaichi, Y.; Kato, A.; Inoue, T.; Koyama, T.
Effects of co-administration of antidepressants and monoamine oxidase inhibitors on 5-HT-related behavior in rats
Eur. J. Pharmacol.
565
105-112
2007
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338), Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Savitha, S.; Naveen, B.; Panneerselvam, C.
Carnitine and lipoate ameliorates lipofuscin accumulation and monoamine oxidase activity in aged rat heart
Eur. J. Pharmacol.
574
61-65
2007
Rattus norvegicus
Manually annotated by BRENDA team
Ballesteros, J.; Maeztu, A.I.; Callado, L.F.; Meana, J.J.; Gutierrez, M.
Specific binding of [3H]Ro 19-6327 (lazabemide) to monoamine oxidase B is increased in frontal cortex of suicide victims after controlling for age at death
Eur. Neuropsychopharmacol.
18
55-61
2008
Homo sapiens (P27338)
Manually annotated by BRENDA team
Arrojo, M.; Baca-Garcia, E.; Perez-Rodriguez, M.M.; Dolengevich-Segal, H.; Navio-Acosta, M.; Rodriguez-Salgado, B.; Saiz-Ruiz, J.
Platelet monoamine oxidase activity in obsessive-compulsive disorder
Eur. Psychiatry
22
525-529
2007
Homo sapiens
Manually annotated by BRENDA team
Coatrieux, C.; Sanson, M.; Negre-Salvayre, A.; Parini, A.; Hannun, Y.; Itohara, S.; Salvayre, R.; Auge, N.
MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway
Free Radic. Biol. Med.
43
80-89
2007
Oryctolagus cuniculus
Manually annotated by BRENDA team
Hong, K.W.; Hayasaka, I.; Murayama, Y.; Ito, S.; Inoue-Murayama, M.
Comparative analysis of monoamine oxidase intronic polymorphisms in primates
Gene
418
9-14
2008
Callithrix jacchus, Cebus albifrons, Colobus guereza, Gorilla gorilla, Hylobates lar, Macaca arctoides, Macaca assamensis, Macaca brunnescens, Macaca cyclopis, Macaca fascicularis, Macaca fuscata, Macaca hecki, Macaca maura, Macaca mulatta, Macaca nemestrina, Macaca nigra, Macaca ochreata, Macaca radiata, Macaca silenus, Macaca sinica, Macaca sylvanus, Macaca thibetana, Macaca tonkeana, Mandrillus sphinx, Miopithecus talapoin, Pan troglodytes, Pan troglodytes (Q5UL86), Pongo pygmaeus, Saguinus oedipus, Saimiri sciureus, Trachypithecus francoisi
Manually annotated by BRENDA team
Basu, N.; Scheuhammer, A.M.; Evans, R.D.; OBrien, M.; Chan, H.M.
Cholinesterase and monoamine oxidase activity in relation to mercury levels in the cerebral cortex of wild river otters
Hum. Exp. Toxicol.
26
213-220
2007
Lontra canadensis
Manually annotated by BRENDA team
Akkermann, K.; Paaver, M.; Nordquist, N.; Oreland, L.; Harro, J.
Association of 5-HTT gene polymorphism, platelet MAO activity, and drive for thinness in a population-based sample of adolescent girls
Int. J. Eat. Disord.
41
399-404
2008
Homo sapiens
Manually annotated by BRENDA team
Herraiz, T.
Identification and occurrence of beta-carboline alkaloids in raisins and inhibition of monoamine oxidase (MAO)
J. Agric. Food Chem.
55
8534-8540
2007
Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Kay, C.W.; El Mkami, H.; Molla, G.; Pollegioni, L.; Ramsay, R.R.
Characterization of the covalently bound anionic flavin radical in monoamine oxidase A by electron paramagnetic resonance
J. Am. Chem. Soc.
129
16091-16097
2007
Homo sapiens (P21397)
Manually annotated by BRENDA team
Olsen, H.T.; Stafford, G.I.; van Staden, J.; Christensen, S.B.; Jaeger, A.K.
Isolation of the MAO-inhibitor naringenin from Mentha aquatica L
J. Ethnopharmacol.
117
500-502
2008
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Leonetti, F.; Capaldi, C.; Pisani, L.; Nicolotti, O.; Muncipinto, G.; Stefanachi, A.; Cellamare, S.; Caccia, C.; Carotti, A.
Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoamine oxidase
J. Med. Chem.
50
4909-4916
2007
Homo sapiens (P27338)
Manually annotated by BRENDA team
Carotti, A.; Catto, M.; Leonetti, F.; Campagna, F.; Soto-Otero, R.; Mendez-Alvarez, E.; Thull, U.; Testa, B.; Altomare, C.
Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives
J. Med. Chem.
50
5364-5371
2007
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Binda, C.; Wang, J.; Pisani, L.; Caccia, C.; Carotti, A.; Salvati, P.; Edmondson, D.E.; Mattevi, A.
Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs
J. Med. Chem.
50
5848-5852
2007
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Chimenti, F.; Maccioni, E.; Secci, D.; Bolasco, A.; Chimenti, P.; Granese, A.; Befani, O.; Turini, P.; Alcaro, S.; Ortuso, F.; Cardia, M.C.; Distinto, S.
Selective inhibitory activity against MAO and molecular modeling studies of 2-thiazolylhydrazone derivatives
J. Med. Chem.
50
707-712
2007
Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
La Regina, G.; Silvestri, R.; Artico, M.; Lavecchia, A.; Novellino, E.; Befani, O.; Turini, P.; Agostinelli, E.
New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity
J. Med. Chem.
50
922-931
2007
Bos taurus (P21398), Bos taurus (P56560)
Manually annotated by BRENDA team
Jensen, S.B.; Di Santo, R.; Olsen, A.K.; Pedersen, K.; Costi, R.; Cirilli, R.; Cumming, P.
Synthesis and cerebral uptake of 1-(1-[(11)C]methyl-1H-pyrrol-2-yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone, a novel tracer for positron emission tomography studies of monoamine oxidase type A
J. Med. Chem.
51
1617-1622
2008
Sus scrofa (Q6Q2J0), Sus scrofa
Manually annotated by BRENDA team
Akyuez, M.A.; Erdem, S.S.; Edmondson, D.E.
The aromatic cage in the active site of monoamine oxidase B: effect on the structural and electronic properties of bound benzylamine and p-nitrobenzylamine
J. Neural Transm.
114
693-698
2007
Homo sapiens (P27338)
Manually annotated by BRENDA team
Cruz, F.; Edmondson, D.E.
Kinetic properties of recombinant MAO-A on incorporation into phospholipid nanodisks
J. Neural Transm.
114
699-702
2007
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Nordquist, N.; Oreland, L.
Monoallelic expression of MAO-A in skin fibroblasts
J. Neural Transm.
114
713-716
2007
Homo sapiens (P21397)
Manually annotated by BRENDA team
Sunal, S.G.; Yabanoglu, S.; Yesilada, A.; Ucar, G.
Monoamine oxidase inhibitory activities of novel 3,4-dihydroquinolin-(1H)-2-one derivatives
J. Neural Transm.
114
717-719
2007
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Wang, J.; Edmondson, D.E.
Do monomeric vs dimeric forms of MAO-A make a difference? A direct comparison of the catalytic properties of rat and human MAO-As
J. Neural Transm.
114
721-724
2007
Homo sapiens, Homo sapiens (P21397), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Finberg, J.P.; Sader-Mazbar, O.
Modification of L-DOPA pharmacological activity by MAO inhibitors
J. Neural Transm.
114
801-805
2007
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Speiser, Z.; Fine, T.; Litinetsky, L.; Eliash, S.; Blaugrund, E.; Cohen, S.
Differential behavioral syndrome evoked in the rats after multiple doses of SSRI fluoxetine with selective MAO inhibitors rasagiline or selegiline
J. Neural Transm.
115
107-116
2008
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Alia-Klein, N.; Goldstein, R.Z.; Kriplani, A.; Logan, J.; Tomasi, D.; Williams, B.; Telang, F.; Shumay, E.; Biegon, A.; Craig, I.W.; Henn, F.; Wang, G.J.; Volkow, N.D.; Fowler, J.S.
Brain monoamine oxidase A activity predicts trait aggression
J. Neurosci.
28
5099-5104
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
ORourke, A.M.; Wang, E.Y.; Miller, A.; Podar, E.M.; Scheyhing, K.; Huang, L.; Kessler, C.; Gao, H.; Ton-Nu, H.T.; Macdonald, M.T.; Jones, D.S.; Linnik, M.D.
Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity
J. Pharmacol. Exp. Ther.
324
867-875
2008
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Baler, R.D.; Volkow, N.D.; Fowler, J.S.; Benveniste, H.
Is fetal brain monoamine oxidase inhibition the missing link between maternal smoking and conduct disorders?
J. Psychiatry Neurosci.
33
187-195
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Ogunrombi, M.O.; Malan, S.F.; TerreBlanche, G.; Castagnoli, K.; Castagnoli, N.; Bergh, J.J.; Petzer, J.P.
Neurotoxicity studies with the monoamine oxidase B substrate 1-methyl-3-phenyl-3-pyrroline
Life Sci.
81
458-467
2007
Bos taurus (P56560), Mus musculus, Mus musculus (Q8BW75), Papio sp.
Manually annotated by BRENDA team
Gabilondo, A.M.; Hostalot, C.; Garibi, J.M.; Meana, J.J.; Callado, L.F.
Monoamine oxidase B activity is increased in human gliomas
Neurochem. Int.
52
230-234
2008
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Ramadan, Z.B.; Wrang, M.L.; Tipton, K.F.
Species differences in the selective inhibition of monoamine oxidase (1-methyl-2-phenylethyl)hydrazine and its potentiation by cyanide
Neurochem. Res.
32
1783-1790
2007
Bos taurus (P56560), Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
MacKenzie, E.M.; Grant, S.L.; Baker, G.B.; Wood, P.L.
Phenelzine causes an increase in brain ornithine that is prevented by prior monoamine oxidase inhibition
Neurochem. Res.
33
430-436
2008
Rattus norvegicus
Manually annotated by BRENDA team
Cicin-Sain, L.; Matosic, A.; Mokrovic, G.; Balija, M.; Marusic, S.; Jernej, B.
Platelet monoamine oxidase kinetics, alcoholism subtypes and cigarette smoking
Neuropsychobiology
56
138-145
2007
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Kersting, A.; Kroker, K.; Horstmann, J.; Baune, B.T.; Hohoff, C.; Mortensen, L.S.; Neumann, L.C.; Arolt, V.; Domschke, K.
Association of MAO-A variant with complicated grief in major depression
Neuropsychobiology
56
191-196
2007
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Sjoeberg, R.L.; Ducci, F.; Barr, C.S.; Newman, T.K.; Dellosso, L.; Virkkunen, M.; Goldman, D.
A non-additive interaction of a functional MAO-A VNTR and testosterone predicts antisocial behavior
Neuropsychopharmacology
33
425-430
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
He, X.J.; Uetsuka, K.; Nakayama, H.
Neural progenitor cells are protected against MPTP by MAO-B inhibitors
Neurotoxicology
29
1141-1146
2008
Mus musculus (Q8BW75)
Manually annotated by BRENDA team
Carpene, C.; Iffiu-Soltesz, Z.; Bour, S.; Prevot, D.; Valet, P.
Reduction of fat deposition by combined inhibition of monoamine oxidases and semicarbazide-sensitive amine oxidases in obese Zucker rats
Pharmacol. Res.
56
522-530
2007
Rattus norvegicus
Manually annotated by BRENDA team
Prevot, D.; Soltesz, Z.; Abello, V.; Wanecq, E.; Valet, P.; Unzeta, M.; Carpene, C.
Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats
Pharmacol. Res.
56
70-79
2007
Rattus norvegicus
Manually annotated by BRENDA team
Carpene, C.; Abello, V.; Iffiu-Soltesz, Z.; Mercier, N.; Feve, B.; Valet, P.
Limitation of adipose tissue enlargement in rats chronically treated with semicarbazide-sensitive amine oxidase and monoamine oxidase inhibitors
Pharmacol. Res.
57
426-434
2008
Rattus norvegicus
Manually annotated by BRENDA team
Frazzetto, G.; Di Lorenzo, G.; Carola, V.; Proietti, L.; Sokolowska, E.; Siracusano, A.; Gross, C.; Troisi, A.
Early trauma and increased risk for physical aggression during adulthood: the moderating role of MAOA genotype
PLoS ONE
2
e486
2007
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Mallajosyula, J.K.; Kaur, D.; Chinta, S.J.; Rajagopalan, S.; Rane, A.; Nicholls, D.G.; Di Monte, D.A.; Macarthur, H.; Andersen, J.K.
MAO-B elevation in mouse brain astrocytes results in Parkinsons pathology
PLoS ONE
3
e1616
2008
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Al-Wabel, N.A.
Comparative activities of semicarbazide-sensitive amine oxidase (SSAO) in five domestic species
Pol. J. Vet. Sci.
11
63-66
2008
Bos taurus, Camelus bactrianus, Capra hircus, Equus caballus, Ovis aries
Manually annotated by BRENDA team
Culpepper, L.; Kovalick, L.J.
A review of the literature on the selegiline transdermal system: an effective and well-tolerated monoamine oxidase inhibitor for the treatment of depression
Prim. Care Companion J. Clin. Psychiatry
10
25-30
2008
Homo sapiens
Manually annotated by BRENDA team
Tadic, A.; Rujescu, D.; Mueller, M.J.; Kohnen, R.; Stassen, H.H.; Dahmen, N.; Szegedi, A.
A monoamine oxidase B gene variant and short-term antidepressant treatment response
Prog. Neuropsychopharmacol. Biol. Psychiatry
31
1370-1377
2007
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Muck-Seler, D.; Sagud, M.; Mustapic, M.; Nedic, G.; Babic, A.; Mihaljevic Peles, A.; Jakovljevic, M.; Pivac, N.
The effect of lamotrigine on platelet monoamine oxidase type B activity in patients with bipolar depression
Prog. Neuropsychopharmacol. Biol. Psychiatry
32
1195-1198
2008
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Domschke, K.; Hohoff, C.; Mortensen, L.S.; Roehrs, T.; Deckert, J.; Arolt, V.; Baune, B.T.
Monoamine oxidase A variant influences antidepressant treatment response in female patients with Major Depression
Prog. Neuropsychopharmacol. Biol. Psychiatry
32
224-228
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Lee, B.C.; Yang, J.W.; Lee, S.H.; Kim, S.H.; Joe, S.H.; Jung, I.K.; Choi, I.G.; Ham, B.J.
An interaction between the norepinephrine transporter and monoamine oxidase A polymorphisms, and novelty-seeking personality traits in Korean females
Prog. Neuropsychopharmacol. Biol. Psychiatry
32
238-242
2008
Homo sapiens (P21397)
Manually annotated by BRENDA team
Upadhyay, A.K.; Edmondson, D.E.
Characterization of detergent purified recombinant rat liver monoamine oxidase B expressed in Pichia pastoris
Protein Expr. Purif.
59
349-356
2008
Rattus norvegicus (P19643)
Manually annotated by BRENDA team
Alia-Klein, N.; Kriplani, A.; Pradhan, K.; Ma, J.Y.; Logan, J.; Williams, B.; Craig, I.W.; Telang, F.; Tomasi, D.; Goldstein, R.Z.; Wang, G.J.; Volkow, N.D.; Fowler, J.S.
The MAO-A genotype does not modulate resting brain metabolism in adults
Psychiatry Res.
164
73-76
2008
Homo sapiens (P21397)
Manually annotated by BRENDA team
Franke, R.M.; Belluzzi, J.D.; Leslie, F.M.
Gestational exposure to nicotine and monoamine oxidase inhibitors influences cocaine-induced locomotion in adolescent rats
Psychopharmacology
195
117-124
2007
Rattus norvegicus
Manually annotated by BRENDA team
Halberstadt, A.L.; Buell, M.R.; Masten, V.L.; Risbrough, V.B.; Geyer, M.A.
Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors
Psychopharmacology
201
55-66
2008
Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Guersoy, S.; Erdal, E.; Sezgin, M.; Barlas, I.O.; Aydeniz, A.; Alasehirli, B.; Sahin, G.
Which genotype of MAO gene that the patients have are likely to be most susceptible to the symptoms of fibromyalgia?
Rheumatol. Int.
28
307-311
2008
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Real, C.; Popa, D.; Seif, I.; Callebert, J.; Launay, J.M.; Adrien, J.; Escourrou, P.
Sleep apneas are increased in mice lacking monoamine oxidase A
Sleep
30
1295-1302
2007
Mus musculus (Q64133)
Manually annotated by BRENDA team
Lecht, S.; Haroutiunian, S.; Hoffman, A.; Lazarovici, P.
Rasagiline - a novel MAO B inhibitor in Parkinsons disease therapy
Ther. Clin. Risk Manag.
3
467-474
2007
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Buckholtz, J.W.; Meyer-Lindenberg, A.
MAOA and the neurogenetic architecture of human aggression
Trends Neurosci.
31
120-129
2008
Homo sapiens (P21397)
Manually annotated by BRENDA team
Lee, S.A.; Hwang, J.S.; Han, X.H.; Lee, C.; Lee, M.H.; Choe, S.G.; Hong, S.S.; Lee, D.; Lee, M.K.; Hwang, B.Y.
Methylpiperate derivatives from Piper longum and their inhibition of monoamine oxidase
Arch. Pharm. Res.
31
679-683
2008
Mus musculus, Mus musculus (Q64133), Mus musculus (Q8BW75)
Manually annotated by BRENDA team
Osman, M.Y.; Osman, H.M.
Inhibitory effect of acetylcholine on monoamine oxidase A and B activity in different parts of rat brain
Arzneimittelforschung
58
493-496
2008
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Upadhyay, A.K.; Borbat, P.P.; Wang, J.; Freed, J.H.; Edmondson, D.E.
Determination of the oligomeric states of human and rat monoamine oxidases in the outer mitochondrial membrane and octyl beta-D-glucopyranoside micelles using pulsed dipolar electron spin resonance spectroscopy
Biochemistry
47
1554-1566
2008
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338), Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Binda, C.; Wang, J.; Li, M.; Hubalek, F.; Mattevi, A.; Edmondson, D.E.
Structural and mechanistic studies of arylalkylhydrazine inhibition of human monoamine oxidases A and B
Biochemistry
47
5616-5625
2008
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Upadhyay, A.K.; Edmondson, D.E.
Development of spin-labeled pargyline analogues as specific inhibitors of human monoamine oxidases A and B
Biochemistry
48
3928-3935
2009
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Gooden, D.M.; Schmidt, D.M.; Pollock, J.A.; Kabadi, A.M.; McCafferty, D.G.
Facile synthesis of substituted trans-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B
Bioorg. Med. Chem. Lett.
18
3047-3051
2008
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Van der Walt, E.M.; Milczek, E.M.; Malan, S.F.; Edmondson, D.E.; Castagnoli, N.; Bergh, J.J.; Petzer, J.P.
Inhibition of monoamine oxidase by (E)-styrylisatin analogues
Bioorg. Med. Chem. Lett.
19
2509-2513
2009
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
MacKenzie, E.M.; Fassihi, A.; Davood, A.; Chen, Q.H.; Rauw, G.; Rauw, G.; Knaus, E.E.; Baker, G.B.
N-Propynyl analogs of beta-phenylethylidenehydrazines: synthesis and evaluation of effects on glycine, GABA, and monoamine oxidase
Bioorg. Med. Chem.
16
8254-8263
2008
Rattus norvegicus (P19643), Rattus norvegicus (P21936)
Manually annotated by BRENDA team
Vilches-Herrera, M.; Miranda-Sepulveda, J.; Rebolledo-Fuentes, M.; Fierro, A.; Luehr, S.; Iturriaga-Vasquez, P.; Cassels, B.K.; Reyes-Parada, M.
Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors
Bioorg. Med. Chem.
17
2452-2460
2009
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Prins, L.H.; Petzer, J.P.; Malan, S.F.
Synthesis and in vitro evaluation of pteridine analogues as monoamine oxidase B and nitric oxide synthase inhibitors
Bioorg. Med. Chem.
17
7523-7530
2009
Papio sp.
Manually annotated by BRENDA team
Zhao, H.; Flamand, V.; Peehl, D.M.
Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells
BMC Med. Genomics
2
55
2009
Homo sapiens
Manually annotated by BRENDA team
Senatori, O.; Setini, A.; Scirocco, A.; Nicotra, A.
Effect of short-time exposures to nickel and lead on brain monoamine oxidase from Danio rerio and Poecilia reticulata
Environ. Toxicol.
24
309-313
2009
Danio rerio, Danio rerio (Q6NSN2), Poecilia reticulata, Poecilia reticulata (Q0PGS2)
Manually annotated by BRENDA team
Wu, J.B.; Chen, K.; Li, Y.; Lau, Y.F.; Shih, J.C.
Regulation of monoamine oxidase A by the SRY gene on the Y chromosome
FASEB J.
23
4029-4038
2009
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
Dunn, R.V.; Marshall, K.R.; Munro, A.W.; Scrutton, N.S.
The pH dependence of kinetic isotope effects in monoamine oxidase A indicates stabilization of the neutral amine in the enzyme-substrate complex
FEBS J.
275
3850-3858
2008
Homo sapiens (P21397)
Manually annotated by BRENDA team
Wang, J.; Harris, J.; Mousseau, D.D.; Edmondson, D.E.
Mutagenic probes of the role of Ser209 on the cavity shaping loop of human monoamine oxidase A
FEBS J.
276
4569-4581
2009
Homo sapiens, Homo sapiens (P21397)
Manually annotated by BRENDA team
van Diermen, D.; Marston, A.; Bravo, J.; Reist, M.; Carrupt, P.A.; Hostettmann, K.
Monoamine oxidase inhibition by Rhodiola rosea L. roots
J. Ethnopharmacol.
122
397-401
2009
Homo sapiens (P27338)
Manually annotated by BRENDA team
Milczek, E.M.; Bonivento, D.; Binda, C.; Mattevi, A.; McDonald, I.A.; Edmondson, D.E.
Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B
J. Med. Chem.
51
8019-8026
2008
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Sallinen, V.; Sundvik, M.; Reenilae, I.; Peitsaro, N.; Khrustalyov, D.; Anichtchik, O.; Toleikyte, G.; Kaslin, J.; Panula, P.
Hyperserotonergic phenotype after monoamine oxidase inhibition in larval zebrafish
J. Neurochem.
109
403-415
2009
Danio rerio, Danio rerio Turku
Manually annotated by BRENDA team
Perez-Neri, I.; Montes, S.; Rios, C.
Inhibitory effect of dehydroepiandrosterone on brain monoamine oxidase activity: in vivo and in vitro studies
Life Sci.
85
652-656
2009
Rattus norvegicus (P19643), Rattus norvegicus (P21396), Rattus norvegicus
Manually annotated by BRENDA team
Adjou, K.T.; Dilda, P.; Aumond, P.; Gueddari, S.; Deslys, J.P.; Dormont, D.; Seman, M.
Increase of monoamine oxidase-B activity in the brain of scrapie-infected hamsters
Neurochem. Int.
52
1416-1421
2008
Mesocricetus auratus
Manually annotated by BRENDA team
Yoo, H.J.; Lee, S.K.; Park, M.; Cho, I.H.; Hyun, S.H.; Lee, J.C.; Yang, S.Y.; Kim, S.A.
Family- and population-based association studies of monoamine oxidase A and autism spectrum disorders in Korean
Neurosci. Res.
63
172-176
2009
Homo sapiens
Manually annotated by BRENDA team
Petzer, J.P.; Castagnoli, N.; Schwarzschild, M.A.; Chen, J.F.; Van der Schyf, C.J.
Dual-target-directed drugs that block monoamine oxidase B and adenosine A(2A) receptors for Parkinsons disease
Neurotherapeutics
6
141-151
2009
Homo sapiens (P27338), Mus musculus
Manually annotated by BRENDA team
Wang, J.; Edmondson, D.E.
High-level expression and purification of rat monoamine oxidase A (MAO A) in Pichia pastoris: comparison with human MAO A
Protein Expr. Purif.
70
211-217
2009
Rattus norvegicus (P21396), Rattus norvegicus
Manually annotated by BRENDA team
van der Vegt, E.J.; Oostra, B.A.; Arias-Vasquez, A.; van der Ende, J.; Verhulst, F.C.; Tiemeier, H.
High activity of monoamine oxidase A is associated with externalizing behaviour in maltreated and nonmaltreated adoptees
Psychiatr. Genet.
19
209-211
2009
Homo sapiens
Manually annotated by BRENDA team
Real, C.; Seif, I.; Adrien, J.; Escourrou, P.
Ondansetron and fluoxetine reduce sleep apnea in mice lacking monoamine oxidase A
Respir. Physiol. Neurobiol.
168
230-238
2009
Mus musculus
Manually annotated by BRENDA team
Saba, W.; Valette, H.; Peyronneau, M.A.; Bramoulle, Y.; Coulon, C.; Curet, O.; George, P.; Dolle, F.; Bottlaender, M.
[(11)C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate
Synapse
64
61-69
2009
Papio sp.
Manually annotated by BRENDA team
Saidemberg, D.M.; Ferreira, M.A.; Takahashi, T.N.; Gomes, P.C.; Cesar-Tognoli, L.M.; da Silva-Filho, L.C.; Tormena, C.F.; da Silva, G.V.; Palma, M.S.
Monoamine oxidase inhibitory activities of indolylalkaloid toxins from the venom of the colonial spider Parawixia bistriata: functional characterization of PwTX-I
Toxicon
54
717-724
2009
Homo sapiens
Manually annotated by BRENDA team
Iagodina, O.
Comparative study of catalytic properties of mink and rat liver monoamine oxidase
Zh. Evol. Biokhim. Fiziol.
44
570-576
2008
Neovison vison, Rattus norvegicus
Manually annotated by BRENDA team
Ravikumar, K.; Sridhar, B.
Two polymorphs of safinamide, a selective and reversible inhibitor of monoamine oxidase B
Acta Crystallogr. Sect. C
66
o317-o320
2010
Homo sapiens
Manually annotated by BRENDA team
Shen, H.W.; Wu, C.; Jiang, X.L.; Yu, A.M.
Effects of monoamine oxidase inhibitor and cytochrome P450 2D6 status on 5-methoxy-N,N-dimethyltryptamine metabolism and pharmacokinetics
Biochem. Pharmacol.
80
122-128
2010
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Edmondson, D.E.; Binda, C.; Wang, J.; Upadhyay, A.K.; Mattevi, A.
Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases
Biochemistry
48
4220-4230
2009
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Jia, Z.; Wei, S.; Zhu, Q.
Monoamine oxidase inhibitors: benzylidene-prop-2-ynyl-amines analogues
Biol. Pharm. Bull.
33
725-728
2010
Homo sapiens
Manually annotated by BRENDA team
Alcaro, S.; Gaspar, A.; Ortuso, F.; Milhazes, N.; Orallo, F.; Uriarte, E.; Yanez, M.; Borges, F.
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B
Bioorg. Med. Chem. Lett.
20
2709-2712
2010
Homo sapiens
Manually annotated by BRENDA team
Geldenhuys, W.J.; Darvesh, A.S.; Funk, M.O.; Van der Schyf, C.J.; Carroll, R.T.
Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening
Bioorg. Med. Chem. Lett.
20
5295-5298
2010
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Manley-King, C.I.; TerreBlanche, G.; Castagnoli, N.; Bergh, J.J.; Petzer, J.P.
Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides
Bioorg. Med. Chem.
17
3104-3110
2009
Papio sp.
Manually annotated by BRENDA team
Goekhan-Kelekci, N.; Simsek, O.O.; Ercan, A.; Yelekci, K.; Sahin, Z.S.; I?ik, S.; Ucar, G.; Bilgin, A.A.
Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors
Bioorg. Med. Chem.
17
6761-6772
2009
Rattus norvegicus
Manually annotated by BRENDA team
Strydom, B.; Malan, S.F.; Castagnoli, N.; Bergh, J.J.; Petzer, J.P.
Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues
Bioorg. Med. Chem.
18
1018-1028
2010
Homo sapiens, Papio anubis
Manually annotated by BRENDA team
Luehr, S.; Vilches-Herrera, M.; Fierro, A.; Ramsay, R.R.; Edmondson, D.E.; Reyes-Parada, M.; Cassels, B.K.; Iturriaga-Vasquez, P.
2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors
Bioorg. Med. Chem.
18
1388-1395
2010
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Shi, L.; Yang, Y.; Li, Z.L.; Zhu, Z.W.; Liu, C.H.; Zhu, H.L.
Design of novel nicotinamides as potent and selective monoamine oxidase a inhibitors
Bioorg. Med. Chem.
18
1659-1664
2010
Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Chimenti, F.; Secci, D.; Bolasco, A.; Chimenti, P.; Granese, A.; Carradori, S.; Maccioni, E.; Cardia, M.C.; Yanez, M.; Orallo, F.; Alcaro, S.; Ortuso, F.; Cirilli, R.; Ferretti, R.; Distinto, S.; Kirchmair, J.; Langer, T.
Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors
Bioorg. Med. Chem.
18
5063-5070
2010
Homo sapiens
Manually annotated by BRENDA team
Chimenti, F.; Bolasco, A.; Secci, D.; Chimenti, P.; Granese, A.; Carradori, S.; Yanez, M.; Orallo, F.; Ortuso, F.; Alcaro, S.
Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors
Bioorg. Med. Chem.
18
5715-5723
2010
Homo sapiens
Manually annotated by BRENDA team
Sugimoto, H.; Taguchi, Y.D.; Shibata, K.; Kinemuchi, H.
Molecular characteristics of a single and novel form of carp (Cyprinus carpio) monoamine oxidase
Comp. Biochem. Physiol. B
155
266-271
2010
Cyprinus carpio
Manually annotated by BRENDA team
Yagodina, O.
Enzymological characteristic of monoamine oxidase from the visual ganglia of the Pacific squid Todarodes pacificus
Dokl. Biochem. Biophys.
428
284-287
2009
Todarodes pacificus
Manually annotated by BRENDA team
Ke, S.; Qian, X.; Liu, F.; Wang, N.; Yang, Q.; Li, Z.
Novel 4H-1,3,4-oxadiazin-5(6H)-ones with hydrophobic and long alkyl chains: design, synthesis, and bioactive diversity on inhibition of monoamine oxidase, chitin biosynthesis and tumor cell
Eur. J. Med. Chem.
44
2113-2121
2009
Homo sapiens
Manually annotated by BRENDA team
Prins, L.H.; Petzer, J.P.; Malan, S.F.
Inhibition of monoamine oxidase by indole and benzofuran derivatives
Eur. J. Med. Chem.
45
4458-4466
2010
Homo sapiens (P27338)
Manually annotated by BRENDA team
Maccioni, E.; Alcaro, S.; Orallo, F.; Cardia, M.C.; Distinto, S.; Costa, G.; Yanez, M.; Sanna, M.L.; Vigo, S.; Meleddu, R.; Secci, D.
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase
Eur. J. Med. Chem.
45
4490-4498
2010
Homo sapiens
Manually annotated by BRENDA team
Herraiz, T.; Gonzalez, D.; Ancin-Azpilicueta, C.; Aran, V.J.; Guillen, H.
beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO)
Food Chem. Toxicol.
48
839-845
2010
Homo sapiens
Manually annotated by BRENDA team
Herraiz, T.; Aran, V.J.; Guillen, H.
Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO)
Free Radic. Res.
43
975-984
2009
Homo sapiens
Manually annotated by BRENDA team
Hu, K.; Zhang, L.; Li, X.; Zhao, S.
Rapid screening of monoamine oxidase B inhibitors in natural extracts by capillary electrophoresis after enzymatic reaction at capillary inlet
J. Chromatogr. B
878
3156-3160
2010
Homo sapiens
Manually annotated by BRENDA team
Goren, T.; Adar, L.; Sasson, N.; Weiss, Y.M.
Clinical pharmacology tyramine challenge study to determine the selectivity of the monoamine oxidase type B (MAO-B) inhibitor rasagiline
J. Clin. Pharmacol.
50
1420-1428
2010
Homo sapiens
Manually annotated by BRENDA team
Chimenti, F.; Secci, D.; Bolasco, A.; Chimenti, P.; Bizzarri, B.; Granese, A.; Carradori, S.; Yanez, M.; Orallo, F.; Ortuso, F.; Alcaro, S.
Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins
J. Med. Chem.
52
1935-1942
2009
Homo sapiens
Manually annotated by BRENDA team
Chimenti, F.; Fioravanti, R.; Bolasco, A.; Chimenti, P.; Secci, D.; Rossi, F.; Yanez, M.; Orallo, F.; Ortuso, F.; Alcaro, S.
Chalcones: a valid scaffold for monoamine oxidases inhibitors
J. Med. Chem.
52
2818-2824
2009
Homo sapiens
Manually annotated by BRENDA team
Pisani, L.; Muncipinto, G.; Miscioscia, T.F.; Nicolotti, O.; Leonetti, F.; Catto, M.; Caccia, C.; Salvati, P.; Soto-Otero, R.; Mendez-Alvarez, E.; Passeleu, C.; Carotti, A.
Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: development and biopharmacological profiling of 7-[(3-chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, revers
J. Med. Chem.
52
6685-6706
2009
Rattus norvegicus
Manually annotated by BRENDA team
Dreiseitel, A.; Korte, G.; Schreier, P.; Oehme, A.; Locher, S.; Domani, M.; Hajak, G.; Sand, P.G.
Berry anthocyanins and their aglycons inhibit monoamine oxidases A and B
Pharmacol. Res.
59
306-311
2009
Homo sapiens
Manually annotated by BRENDA team
Arslan, B.K.; Edmondson, D.E.
Expression of zebrafish (Danio rerio) monoamine oxidase (MAO) in Pichia pastoris: purification and comparison with human MAO A and MAO B
Protein Expr. Purif.
70
290-297
2010
Danio rerio
Manually annotated by BRENDA team
Ramsay, R.R.; Olivieri, A.; Holt, A.
An improved approach to steady-state analysis of monoamine oxidases
J. Neural Transm.
118
1003-1019
2011
Homo sapiens (P27338)
Manually annotated by BRENDA team
McDonald, G.R.; Olivieri, A.; Ramsay, R.R.;, Holt, A.
On the formation and nature of the imidazoline I2 binding site on human monoamine oxidase-B
Pharmacol. Res.
62
475-488
2010
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Zhang, Y.; Livingstone, J.; Hirasawa, E.
Purification and characterisation of monoamine oxidase from Avena sativa
Acta Physiol. Plant.
34
1411-1419
2012
Avena sativa
-
Manually annotated by BRENDA team
Wang, J.; Edmondson, D.E.
2H kinetic isotope effects and pH dependence of catalysis as mechanistic probes of rat monoamine oxidase A: comparisons with the human enzyme
Biochemistry
50
7710-7717
2011
Rattus norvegicus
Manually annotated by BRENDA team
Carroll, R.T.; Dluzen, D.E.; Stinnett, H.; Awale, P.S.; Funk, M.O.; Geldenhuys, W.J.
Structure-activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B
Bioorg. Med. Chem. Lett.
21
4798-4803
2011
Homo sapiens
Manually annotated by BRENDA team
Cui, Z.; Zhang, Y.; Inoue, H.; Yogo, S.; Hirasawa, E.
Purification and molecular analysis of a monoamine oxidase isolated from Narcissus tazetta
Biosci. Biotechnol. Biochem.
77
1728-1733
2013
Narcissus tazetta
Manually annotated by BRENDA team
Aldeco, M.; Arslan, B.K.; Edmondson, D.E.
Catalytic and inhibitor binding properties of zebrafish monoamine oxidase (zMAO): comparisons with human MAO A and MAO B
Comp. Biochem. Physiol. B
159
78-83
2011
Danio rerio
Manually annotated by BRENDA team
Milczek, E.M.; Binda, C.; Rovida, S.; Mattevi, A.; Edmondson, D.E.
The gating residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition
FEBS J.
278
4860-4869
2011
Homo sapiens
Manually annotated by BRENDA team
Yagodina, O.; Basova, I.
Comparative enzymological study of catalytic properties of liver monoamine oxidases in frogs
J. Evol. Biochem. Physiol.
46
350-356
2010
Pelophylax ridibundus, Rana temporaria
-
Manually annotated by BRENDA team
Basova, I.; Yagodina, O.
Catalytic characteristics of monoamine oxidase of whitefish Coregonus lavaretus ludoga
J. Evol. Biochem. Physiol.
47
321-327
2011
Coregonus lavaretus ludoga
-
Manually annotated by BRENDA team
Basova, I.; Yagodina, O.
Reactivity of liver monoamine oxidase in the seal Phoca hispida ladogensis
J. Evol. Biochem. Physiol.
49
138-144
2013
Pusa hispida ladogensis
-
Manually annotated by BRENDA team
Yagodina, O.; Basova, I.
Liver monoamine oxidase activity of the lamprey Lampetra fluviatilis. The substrate-inhibitor specificity
J. Evol. Biochem. Physiol.
49
53-58
2013
Lampetra fluviatilis
-
Manually annotated by BRENDA team
Pisani, L.; Barletta, M.; Soto-Otero, R.; Nicolotti, O.; Mendez-Alvarez, E.; Catto, M.; Introcaso, A.; Stefanachi, A.; Cellamare, S.; Altomare, C.; Carotti, A.
Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors
J. Med. Chem.
56
2651-2664
2013
Rattus norvegicus
Manually annotated by BRENDA team
Mathew, B.; Mathew, G.E.; Ucar, G.; Baysal, I.; Suresh, J.; Vilapurathu, J.K.; Prakasan, A.; Suresh, J.K.; Thomas, A.
Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors Synthesis, biochemistry and molecular docking studies
Bioorg. Chem.
62
22-29
2015
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Sun, Y.; Chen, J.; Chen, X.; Huang, L.; Li, X.
Inhibition of cholinesterase and monoamine oxidase-B activity by tacrine-homoisoflavonoid hybrids
Bioorg. Med. Chem.
21
7406-7417
2013
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Sergutina, A.V.; Rakhmanova, V.I.
Differences in monoamine oxidase activity in the brain of Wistar and August rats with high and low locomotor activity a cytochemical study
Bull. Exp. Biol. Med.
161
211-214
2016
Rattus norvegicus
Manually annotated by BRENDA team
Koc, G.?.; Tan, O.U.; Ucar, G.; Yildirim, E.; Erol, K.; Palaska, E.
Synthesis and monoamine oxidase inhibitory activities of some 3-(4-fluorophenyl)-5-aryl-n-substituted-4,5-dihydro-(1H)-pyrazole-1-carbothioamide derivatives
Drug Res.
64
591-598
2014
Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Tzvetkov, N.T.; Stammler, H.G.; Neumann, B.; Hristova, S.; Antonov, L.; Gastreich, M.
Crystal structures, binding interactions, and ADME evaluation of brain penetrant N-substituted indazole-5-carboxamides as subnanomolar, selective monoamine oxidase B and dual MAO-A/B inhibitors
Eur. J. Med. Chem.
127
470-492
2017
Homo sapiens (P21397), Homo sapiens (P27338), Rattus norvegicus (P19643), Rattus norvegicus (P21396)
Manually annotated by BRENDA team
Bonaiuto, E.; Milelli, A.; Cozza, G.; Tumiatti, V.; Marchetti, C.; Agostinelli, E.; Fimognari, C.; Hrelia, P.; Minarini, A.; Di Paolo, M.L.
Novel polyamine analogues from substrates towards potential inhibitors of monoamine oxidases
Eur. J. Med. Chem.
70
88-101
2013
Homo sapiens, Homo sapiens (P21397), Homo sapiens (P27338)
Manually annotated by BRENDA team
Dasgupta, S.; Mukherjee, S.; Mukhopadhyay, B.P.; Banerjee, A.; Mishra, D.K.
Recognition dynamics of dopamine to human monoamine oxidase B role of Leu171/Gln206 and conserved water molecules in the active site cavity
J. Biomol. Struct. Dyn.
24
1-24
2017
Homo sapiens, Homo sapiens (P27338)
Manually annotated by BRENDA team
Yagodina, O.; Basova, I.
Comparative enzymologic study of catalytical properties of liver monoamine oxidases of sturgeon fish
J. Evol. Biochem. Physiol.
49
300-308
2013
Acipenser gueldenstaedtii, Acipenser persicus, Acipenser stellatus, Huso huso
-
Manually annotated by BRENDA team
Basova, I.; Yagodina, O.
Enzymologic characteristics of monoamine oxidase from liver of the skipjack tuna Katsuwonus pelamis
J. Evol. Biochem. Physiol.
49
562-569
2013
Katsuwonus pelamis
-
Manually annotated by BRENDA team
Basova, I.; Basova, N.; Yagodina, O.
Catalytic properties of liver monoamine oxidase in the chum salmon Oncorhynchus keta
J. Evol. Biochem. Physiol.
51
370-377
2015
Oncorhynchus keta
-
Manually annotated by BRENDA team
Ramesh, H.; Woodley, J.
Process characterization of a monoamine oxidase
J. Mol. Catal. B
106
124-131
2014
Aspergillus niger
-
Manually annotated by BRENDA team
Rios-Solis, L.; Mothia, B.; Yi, S.; Zhou, Y.; Micheletti, M.; Lye, G.
High throughput screening of monoamine oxidase (MAO-N-D5) substrate selectivity and rapid kinetic model generation
J. Mol. Catal. B
120
100-110
2015
Aspergillus niger
-
Manually annotated by BRENDA team
Sampaio, T.B.; Da Rocha, J.T.; Prigol, M.; Saraiva, R.A.; Nogara, P.F.; Stein, A.L.; da Rocha, J.B.; Zeni, G.; Nogueira, C.W.
4-Organoseleno-isoquinolines selectively and reversibly inhibit the cerebral monoamine oxidase B activity
J. Mol. Neurosci.
59
135-145
2016
Rattus norvegicus (P19643)
Manually annotated by BRENDA team
Chaudhuri, A.D.; Yelamanchili, S.V.; Fox, H.S.
MicroRNA-142 reduces monoamine oxidase A expression and activity in neuronal cells by downregulating SIRT1
PLoS ONE
8
e79579
2013
Homo sapiens
Manually annotated by BRENDA team