Disease on EC 1.4.3.3 - D-amino-acid oxidase

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DISEASE
TITLE OF PUBLICATION
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Acidosis
Some aspects of proximal tubular sodium chloride reabsorption in Necturus kidney.
Alzheimer Disease
Benzoate, a D-Amino Acid Oxidase Inhibitor, for the Treatment of Early-Phase Alzheimer Disease: A Randomized, Double-Blind, Placebo-Controlled Trial.
Sodium benzoate for the treatment of behavioral and psychological symptoms of dementia (BPSD): A randomized, double-blind, placebo-controlled, 6-week trial.
Amyotrophic Lateral Sclerosis
Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase.
Insights into the role of d-amino acid oxidase mutations in amyotrophic lateral sclerosis.
Pathogenic effects of amyotrophic lateral sclerosis-linked mutation in D-amino acid oxidase are mediated by D-serine.
Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System.
Anemia
Rat liver D-amino acid oxidase activity in iron deficiency anemia.
Anemia, Iron-Deficiency
Rat liver D-amino acid oxidase activity in iron deficiency anemia.
Ataxia
Mice lacking D-amino acid oxidase activity display marked attenuation of stereotypy and ataxia induced by MK-801.
Bone Neoplasms
Contributions of spinal D-amino acid oxidase to bone cancer pain.
Down-regulation of spinal D-amino acid oxidase expression blocks formalin-induced tonic pain.
Brain Neoplasms
Induction of cytotoxic oxidative stress by D-alanine in brain tumor cells expressing Rhodotorula gracilis D-amino acid oxidase: a cancer gene therapy strategy.
Carcinoma
Peroxisomal enzymes in normal and tumoral human breast.
Carcinoma, Hepatocellular
Functional interactions between oxidative stress, membrane Na(+) permeability, and cell volume in rat hepatoma cells.
[Distribution, after differential centrifugation, of acid hydrolases, catalase, D-amino acid oxidase and urate oxidase in various Morris hepatomas]
Cardiomyopathy, Dilated
Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction.
Reversal of heart failure in a chemogenetic model of persistent cardiac redox stress.
Dementia
A Post-hoc Study of D-Amino Acid Oxidase in Blood as an Indicator of Post-stroke Dementia.
Diabetes Mellitus, Experimental
Influence of insulin status on extra-mitochondrial oxygen metabolism in the rat.
Xanthine oxidase and D-amino-acid oxidase in fatty liver and alloxan diabetes.
Fatty Liver
Xanthine oxidase and D-amino-acid oxidase in fatty liver and alloxan diabetes.
Foot-and-Mouth Disease
Active protein aggregates induced by terminally attached self-assembling peptide ELK16 in Escherichia coli.
Glioblastoma
Characterization of human DAAO variants potentially related to an increased risk of schizophrenia.
Evidence for the interaction of d-amino acid oxidase with pLG72 in a glial cell line.
Identification of DNA-binding proteins that interact with the 5'-flanking region of the human d-amino acid oxidase gene by pull-down assay coupled with two-dimensional gel electrophoresis and mass spectrometry.
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase: effect on schizophrenia susceptibility.
The degradation (by distinct pathways) of human D-amino acid oxidase and its interacting partner pLG72--two key proteins in D-serine catabolism in the brain.
Glioma
D-amino acid oxidase gene therapy sensitizes glioma cells to the antiglycolytic effect of 3-bromopyruvate.
D-Serine metabolism in C6 glioma cells: Involvement of alanine-serine-cysteine transporter (ASCT2) and serine racemase (SRR) but not D-amino acid oxidase (DAO).
Granulomatous Disease, Chronic
PEGylated D-amino acid oxidase restores bactericidal activity of neutrophils in chronic granulomatous disease via hypochlorite.
Heart Failure
Reversal of heart failure in a chemogenetic model of persistent cardiac redox stress.
Hyperalgesia
Contributions of spinal D-amino acid oxidase to chronic morphine-induced hyperalgesia.
Glycine inhibitory dysfunction turns touch into pain through astrocyte-derived d-serine.
Spinal D-Serine Increases PKC-Dependent GluN1 Phosphorylation Contributing to the Sigma-1 Receptor-Induced Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain.
WITHDRAWN: Spinal d-amino acid oxidase contributes to the pathogenesis of hyperalgesia in the rat formalin test.
Hyperoxaluria, Primary
Enzymological characterization of a feline analogue of primary hyperoxaluria type 2: a model for the human disease.
Hyperpigmentation
Evaluation of In Vitro Function by Subcellular Distribution of Lysosomal and Peroxisomal Protein in Saccharomyces cerevisiae.
Hypersensitivity
Spinal D-amino acid oxidase contributes to mechanical pain hypersensitivity induced by sleep deprivation in the rat.
Hyperthyroidism
The effects of postnatal hyper- and hypothyroidism on the development of D-amino acid oxidase in rat cerebellum and brain stem.
Hypokinesia
Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway.
Hypothyroidism
The effects of postnatal hyper- and hypothyroidism on the development of D-amino acid oxidase in rat cerebellum and brain stem.
Infections
Protective Role of D-Amino Acid Oxidase Against Staphylococcus aureus infection.
Salmonella evades D-amino acid oxidase to promote infection in neutrophils.
Malnutrition
Hepatic and renal D-amino acid oxidase activities in the growing rat after ten days of protein undernutrition and refeeding.
Neoplasms
3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects.
D-Aminoacid oxidase and homogentisate oxygenase activities in the tumor bearing rats.
Determination of D-amino acid oxidase activity in tumour cells.
Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin.
Induction of cytotoxic oxidative stress by D-alanine in brain tumor cells expressing Rhodotorula gracilis D-amino acid oxidase: a cancer gene therapy strategy.
Optimization of D-amino acid oxidase for low substrate concentrations--towards a cancer enzyme therapy.
Oxidoreductase activities in normal rat liver, tumor-bearing rat liver, and hepatoma HC-252.
Oxystress inducing antitumor therapeutics via tumor-targeted delivery of PEG-conjugated D-amino acid oxidase.
Peroxisomes in human colon carcinomas. A cytochemical and biochemical study.
THE DETERMINATION OF THE TOTAL D-AMINO ACID CONTENT OF HUMAN TUMORS AND NORMAL TISSUES BY MEANS OF D-AMINO ACID OXIDASE.
Tumor-targeted delivery of polyethylene glycol-conjugated D-amino acid oxidase for antitumor therapy via enzymatic generation of hydrogen peroxide.
Nervous System Diseases
Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation.
Neuralgia
An integrated review on new targets in the treatment of neuropathic pain.
Binding Residence Time through Scaled Molecular Dynamics: A Prospective Application to hDAAO Inhibitors.
Down-regulation of spinal D-amino acid oxidase expression blocks formalin-induced tonic pain.
Drug Therapy of Neuropathic Pain: Current Developments and Future Perspectives.
PHARMACODYNAMIC EFFECTS OF A D-AMINO ACID OXIDASE INHIBITOR INDICATE A SPINAL SITE OF ACTION IN RAT MODELS OF NEUROPATHIC PAIN.
Spinal D-Amino Acid Oxidase Contributes to Neuropathic Pain in Rats.
Neurobehavioral Manifestations
D-amino Acid oxidase inhibitors as a novel class of drugs for schizophrenia therapy.
Drug discovery strategies and the preclinical development of D-amino-acid oxidase inhibitors as antipsychotic therapies.
Lack of Effect of Sodium Benzoate at Reported Clinical Therapeutic Concentration on d-Alanine Metabolism in Dogs.
Neurodegenerative Diseases
The role of D-serine and glycine as co-agonists of NMDA receptors in motor neuron degeneration and amyotrophic lateral sclerosis (ALS).
Peroxisomal Disorders
Pipecolic acid is oxidized by renal and hepatic peroxisomes. Implications for Zellweger's cerebro-hepato-renal syndrome (CHRS).
Polyuria
D-amino-acid oxidase is involved in D-serine-induced nephrotoxicity.
Renal Aminoacidurias
Lack of D-amino-acid oxidase activity causes a specific renal aminoaciduria in the mouse.
Renal Insufficiency
D-Amino acids in chronic renal failure and the effects of dialysis and urinary losses.
Reperfusion Injury
Production of hydrogen sulfide from d-cysteine and its therapeutic potential.
Sarcoma 180
Oxystress inducing antitumor therapeutics via tumor-targeted delivery of PEG-conjugated D-amino acid oxidase.
Sleep Deprivation
Spinal D-amino acid oxidase contributes to mechanical pain hypersensitivity induced by sleep deprivation in the rat.
Spinocerebellar Ataxias
Localization of the candidate gene D-amino acid oxidase outside the refined I-cM region of spinocerebellar ataxia 2.
Staphylococcal Infections
Protective Role of D-Amino Acid Oxidase Against Staphylococcus aureus infection.
Thymoma
An update on the genetics of schizophrenia.
Tuberculosis
The Mycobacterium tuberculosis H37Ra gene MRA_1916 causes growth defects upon down-regulation.
Urinary Bladder, Overactive
Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy.
Zellweger Syndrome
Histochemistry of peroxisomal enzyme activities: a tool in the diagnosis of Zellweger syndrome.
The human L-pipecolic acid oxidase is similar to bacterial monomeric sarcosine oxidases rather than D-amino acid oxidases.