Information on EC 1.3.99.38 - menaquinone-9 beta-reductase

for references in articles please use BRENDA:EC1.3.99.38
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The expected taxonomic range for this enzyme is: Mycobacterium

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EC NUMBER
COMMENTARY hide
1.3.99.38
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RECOMMENDED NAME
GeneOntology No.
menaquinone-9 beta-reductase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
menaquinone-9 + reduced acceptor = beta-dihydromenaquinone-9 + acceptor
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
beta-dihydromenaquinone-9 biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
menaquinone-9 oxidoreductase (beta-dihydromenaquinone-9-forming)
The enzyme from the bacterium Mycobacterium tuberculosis reduces the beta-isoprene unit of menaquinone-9, forming the predominant form of menaquinone found in mycobacteria. Contains FAD.
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
menaquinone-9 + reduced acceptor
beta-dihydromenaquinone-9 + acceptor
show the reaction diagram
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21
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ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
pharmacology
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LINKS TO OTHER DATABASES (specific for EC-Number 1.3.99.38)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)