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Information on EC 1.3.8.14 - L-prolyl-[peptidyl-carrier protein] dehydrogenase

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IUBMB Comments
Contains FAD. The enzyme participates in the biosynthesis of several pyrrole-containing compounds, such as undecylprodigiosin, prodigiosin, pyoluteorin, and coumermycin A1. It is believed to catalyse the formation of a Delta2-pyrrolin-2-carbonyl-[peptidyl-carrier protein] intermediate, followed by a two-electron oxidation to 1H-pyrrol-2-carbonyl-[peptidyl-carrier protein].
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The enzyme appears in viruses and cellular organisms
Synonyms
bmp3, L-prolyl-PCP dehydrogenase, L-prolyl-S-PCP dehydrogenase, PigA, pltE, redW, SC2E9.20, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-prolyl-[peptidyl-carrier protein] + 2 electron-transfer flavoprotein = 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] + 2 reduced electron-transfer flavoprotein
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