show all | hide all No of entries

Information on EC 1.3.1.99 - iridoid synthase

for references in articles please use BRENDA:EC1.3.1.99
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.99 iridoid synthase
IUBMB Comments
Isolated from the plant Catharanthus roseus. The reaction may involve cyclization via a Diels-Alder or Michael reaction. Iridoids are involved in the biosynthesis of many indole alkaloids. The cyclic hemiacetal is readily hydrolysed to the corresponding dial.
Specify your search results
Select one or more organisms in this record:
Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
1,4-Reductase, 10-hydroxygeraniol oxidoreductase, Cr10HGO, CrIS, CrISY, CrP5betaR4, CrP5betaR5, iridoid cyclase, IRIS, ISY, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(6E)-8-oxogeranial + NAD(P)H + H+ = cis-trans-nepetalactol + NAD(P)+
show the reaction diagram
Select items on the left to see more content.