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Information on EC 1.3.1.84 - acrylyl-CoA reductase (NADPH)

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IUBMB Comments
Catalyses a step in the 3-hydroxypropanoate/4-hydroxybutanoate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea . The enzyme from Sulfolobus tokodaii does not act on either NADH or crotonyl-CoA . Different from EC 1.3.1.8, which acts only on enoyl-CoA derivatives of carbon chain length 4 to 16. Contains Zn2+.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
acryloyl-coa reductase, acrylyl-coa reductase, spo_1914, spo1914, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
propanoyl-CoA + NADP+ = acryloyl-CoA + NADPH + H+
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