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Information on EC 1.3.1.8 - acyl-CoA dehydrogenase (NADP+)

for references in articles please use BRENDA:EC1.3.1.8
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IUBMB Comments
The liver enzyme acts on enoyl-CoA derivatives of carbon chain length 4 to 16, with optimum activity on 2-hexenoyl-CoA. In Escherichia coli, cis-specific and trans-specific enzymes exist [EC 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH) and EC 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)].
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
2-enoyl-CoA reductase, 2-trans enoyl-CoA reductase, 2-trans-enoyl-CoA reductase, acyl coenzyme A dehydrogenase (nicotinamide adenine dinucleotide phosphate), CCR, crotonyl CoA reductase, crotonyl coenzyme A reductase, crotonyl-CoA reductase, crotonyl-coenzyme A reductase, dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate), more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+
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