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Information on EC 1.3.1.78 - arogenate dehydrogenase (NADP+)

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IUBMB Comments
Arogenate dehydrogenases may utilize NAD+ (EC 1.3.1.43), NADP+ (EC 1.3.1.78), or both (EC 1.3.1.79). NADP+-dependent enzymes usually predominate in higher plants.The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 and the TyrAAT1 isoform of the plant Arabidopsis thaliana cannot use prephenate as a substrate, while the Arabidopsis isoform TyrAAT2 can use it very poorly [2,3].
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Word Map
  • 1.3.1.78
  • kinase-inactive
  • prephenate
  • gadd45
  • malformation
  • annexin
  • ifngamma
  • neurulation
  • perinuclear
  • calcium-dependent
  • mekks
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
Synonyms
tyraat1, tyrasy, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-arogenate + NADP+ = L-tyrosine + NADPH + CO2
show the reaction diagram
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