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Information on EC 1.3.1.32 - maleylacetate reductase
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EC Tree
1.3.1.32 maleylacetate reductaseSpecify your search results
Word Map
- 1.3.1.32
- chlorocatechols
-
cycloisomerase
- dienelactone
- 2,4-dichlorophenoxyacetate
-
chloroaromatic
- 2-chloromaleylacetate
- resorcinol
-
chloromuconate
- hydroxyquinol
- eutrophus
-
intradiol
-
beta-ketoadipate
- 3-chlorobenzoate
- 4-chlorocatechol
-
lysr-type
- cis-dienelactone
- muconate
-
dehalogenation
-
sphingobium
- trans-dienelactone
- opacus
- chlorophenolicum
- 4-fluorobenzoate
- protoanemonin
-
2-chloro
- biotechnology
- environmental protection
The enzyme appears in viruses and cellular organisms
Synonyms
maleylacetate reductase, 
more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
hqdD
HqoD
HxqD
MAA reductase
maleoylacetate reductase
-
-
-
-
maleylacetate reductase
MAR
PcpE
pdcF
PnpD
TcpD
tfdF
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+
-
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
redox reaction
redox reaction
-
-
-
-
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PATHWAY SOURCE
PATHWAYS
KEGG
-
, , , , , 3-chlorocatechol degradation, 3-chlorocatechol degradation, 3-chlorocatechol degradation, 3-chlorocatechol degradation, 3-chlorocatechol degradation, 3-chlorocatechol degradation, 3-chlorocatechol degradation, 3-chlorocatechol degradation, 3-chlorocatechol degradation, Chlorocyclohexane and chlorobenzene degradation, Fluorobenzoate degradation, Fluorobenzoate degradation, Fluorobenzoate degradation, Microbial metabolism in diverse environments, Microbial metabolism in diverse environments, Microbial metabolism in diverse environments
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SYSTEMATIC NAME
IUBMB Comments
3-oxoadipate:NAD(P)+ oxidoreductase
-
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CAS REGISTRY NUMBER
COMMENTARY
69669-65-4
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2,5-dibromomaleylacetate + NADH
5-bromo-4-oxohex-2-enedioic acid + Br- + NAD+
-
-
-
?
2-bromo-5-chloromaleylacetate + NADH
5-chloro-4-oxohex-2-enedioic acid + Br- + NAD+
-
-
-
?
2-chloro-3-methylmaleylacetate + NADH
3-methyl-4-oxohex-2-enedioic acid + NAD+ + Cl-
-
-
the product is further reduced to 3-methyl-4-oxohexanedioic acid under consumption of NADH
?
2-chloro-5-methylmaleylacetate + NADH
5-methyl-4-oxohex-2-enedioic acid + NAD+ + Cl-
-
-
the product is further reduced to 2-methyl-3-oxohexanedioic acid under consumption of NADH
?
2-chloromaleylacetate + NADH
maleylacetate + NAD+ + Cl-
final enzyme in the pentachlorophenol biodegradation pathway which catalyzes the reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and the subsequent reduction of malyelacetate to 3-oxoadipate
-
-
?
2-chloromaleylacetate + NADPH + H+
maleylacetate + NADP+ + HCl
-
-
-
?
3-fluoromaleylacetate + NADH
2-fluoro-3-oxohexanedioic acid + NAD+
-
-
-
?
2,3,5-trichloromaleylacetate + NADH
2,4-dichloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,3,5-trichloromaleylacetate + NADH
2,4-dichloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,3,5-trichloromaleylacetate + NADH
2,4-dichloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,3,5-trichloromaleylacetate + NADH
2,4-dichloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,3,5-trichloromaleylacetate + NADH
2,4-dichloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,3-dibromomaleylacetate + NADH
3-bromo-4-oxohexanedioic acid + NAD+ + Br-
-
-
-
?
2,3-dibromomaleylacetate + NADH
3-bromo-4-oxohexanedioic acid + NAD+ + Br-
-
-
-
?
2,3-dibromomaleylacetate + NADH
3-bromo-4-oxohexanedioic acid + NAD+ + Br-
-
-
-
?
2,3-dibromomaleylacetate + NADH
3-bromo-4-oxohexanedioic acid + NAD+ + Br-
-
-
-
?
2,3-dibromomaleylacetate + NADH
3-bromo-4-oxohexanedioic acid + NAD+ + Br-
-
-
-
?
2,3-dichloromaleylacetate + NADH
3-chloro-4-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,3-dichloromaleylacetate + NADH
3-chloro-4-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,3-dichloromaleylacetate + NADH
3-chloro-4-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,3-dichloromaleylacetate + NADH
3-chloro-4-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,3-dichloromaleylacetate + NADH
3-chloro-4-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,4-dichlorophenoxyacetate + NADH
?
-
degradation of haloaromatic compounds
-
-
?
2,4-dichlorophenoxyacetate + NADH
?
-
degradation of haloaromatic compounds
-
-
?
2,5-dichloromaleylacetate + NADH
2-chloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,5-dichloromaleylacetate + NADH
2-chloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,5-dichloromaleylacetate + NADH
2-chloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,5-dichloromaleylacetate + NADH
2-chloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2,5-dichloromaleylacetate + NADH
2-chloro-3-oxohexanedioic acid + NAD+ + Cl-
-
-
-
?
2-bromomaleylacetate + NADH
2-maleylacetate + NAD+ + Br-
-
-
-
?
2-bromomaleylacetate + NADH
2-maleylacetate + NAD+ + Br-
-
-
the product is further reduced to 2-bromo-3-oxohexanedioic acid under consumption of NADH
?
2-bromomaleylacetate + NADH
2-maleylacetate + NAD+ + Br-
-
-
the product is further reduced to 2-bromo-3-oxohexanedioic acid under consumption of NADH
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
the product is further reduced to 3-oxoadipate under consumption of NADH
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
the product is further reduced to 3-oxoadipate under consumption of NADH
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
the product is further reduced to 3-oxoadipate under consumption of NADH
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
the product is further reduced to 3-oxoadipate under consumption of NADH
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
-
?
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
-
-
-
-
?
2-chloromaleylacetate + NADH + H+
maleylacetate + NAD+ + Cl-
the enzyme catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-chloromaleylacetate + NADH + H+
maleylacetate + NAD+ + Cl-
the enzyme catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-chloromaleylacetate + NADH + H+
maleylacetate + NAD+ + HCl
-
-
-
?
2-chloromaleylacetate + NADH + H+
maleylacetate + NAD+ + HCl
maleylacetate reductase (PcpE) is the last enzyme in the pentachlorophenol biodegradation pathway in Sphingobium chlorophenolicum L-1. It catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-chloromaleylacetate + NADH + H+
maleylacetate + NAD+ + HCl
-
-
-
?
2-chloromaleylacetate + NADH + H+
maleylacetate + NAD+ + HCl
maleylacetate reductase (PcpE) is the last enzyme in the pentachlorophenol biodegradation pathway in Sphingobium chlorophenolicum L-1. It catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-chloromaleylacetate + NADPH
2-maleylacetate + Cl- + NADP+
-
reductive dehalogenation
-
-
?
2-chloromaleylacetate + NADPH
2-maleylacetate + Cl- + NADP+
-
reductive dehalogenation
-
-
?
2-chloromaleylacetate + NADPH
2-maleylacetate + Cl- + NADP+
-
reductive dehalogenation
-
-
?
2-chloromaleylacetate + NADPH
2-maleylacetate + Cl- + NADP+
-
reductive dehalogenation
-
-
?
2-chloromaleylacetate + NADPH
2-maleylacetate + Cl- + NADP+
-
reductive dehalogenation
-
-
?
2-chloromaleylacetate + NADPH
2-maleylacetate + Cl- + NADP+
-
reductive dehalogenation
-
-
?
2-chloromaleylacetate + NADPH
2-maleylacetate + Cl- + NADP+
-
reductive dehalogenation
-
-
?
2-chloromaleylacetate + NADPH + H+
maleylacetate + NADP+ + Cl-
the enzyme catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-chloromaleylacetate + NADPH + H+
maleylacetate + NADP+ + Cl-
the enzyme catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
chlorobenzene-degrading bacterium strain WR1306
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
enzyme plays a crucial role in the degradation of aromatic compounds
-
-
?
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
enzyme plays a crucial role in the degradation of aromatic compounds
-
-
?
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
-
-
-
-
ir
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
Sporotrichum pulverulentum
-
-
-
-
ir
2-maleylacetate + NAD(P)H + H+
3-oxoadipate + NAD(P)+
i.e. 3-hydroxymuconate
-
-
r
2-maleylacetate + NAD(P)H + H+
3-oxoadipate + NAD(P)+
-
-
-
r
2-maleylacetate + NAD(P)H + H+
3-oxoadipate + NAD(P)+
i.e. 3-hydroxymuconate
-
-
r
2-maleylacetate + NADH + H+
3-oxoadipate + NAD+
maleylacetate reductase (PcpE) is the last enzyme in the pentachlorophenol biodegradation pathway in Sphingobium chlorophenolicum L-1. It catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-maleylacetate + NADH + H+
3-oxoadipate + NAD+
the enzyme catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-maleylacetate + NADH + H+
3-oxoadipate + NAD+
the enzyme catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-maleylacetate + NADH + H+
3-oxoadipate + NAD+
-
-
-
?
2-maleylacetate + NADH + H+
3-oxoadipate + NAD+
maleylacetate reductase (PcpE) is the last enzyme in the pentachlorophenol biodegradation pathway in Sphingobium chlorophenolicum L-1. It catalyzes two consecutive reductive reactions, reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and subsequent reduction of maleylacetate to 3-oxoadipate
-
-
?
2-maleylacetate + NADPH
3-oxoadipate + NADP+
-
-
-
-
ir
2-maleylacetate + NADPH
3-oxoadipate + NADP+
chlorobenzene-degrading bacterium strain WR1306
-
-
-
-
ir
2-maleylacetate + NADPH
3-oxoadipate + NADP+
-
-
-
-
ir