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Information on EC 1.23.1.1 - (+)-pinoresinol reductase

for references in articles please use BRENDA:EC1.23.1.1
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EC Tree
     1 Oxidoreductases
         1.23 Reducing C-O-C group as acceptor
             1.23.1 With NADH or NADPH as donor
                1.23.1.1 (+)-pinoresinol reductase
IUBMB Comments
The reaction is catalysed in vivo in the opposite direction to that shown. A multifunctional enzyme that further reduces the product to the lignan (-)-secoisolariciresinol [EC 1.23.1.2, (+)-lariciresinol reductase]. Isolated from the plants Forsythia intermedia [1,2], Thuja plicata (western red cedar) , Linum perenne (perennial flax) and Linum corymbulosum . The 4-pro-R hydrogen of NADH is transferred to the 7-pro-R position of lariciresinol .
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Word Map
  • 1.23.1.1
  • recombinase
  • meiotic
  • ssdna
  • nucleoprotein
  • fork
  • rpa
  • rad51-mediated
  • presynaptic
  • helicase
  • dna-damaging
  • duplex
  • hrad51
  • stall
  • rad51-dependent
  • chromatid
  • radiosensitivity
  • homology-directed
  • lignans
  • secoisolariciresinol
  • meiosis-specific
  • strand-exchange
  • fanconi
  • reca-like
  • prophase
  • interstrand
  • error-free
  • linum
  • fancd2
  • ssdna-binding
  • brca1/2
  • olaparib
  • podophyllotoxin
  • d-loops
  • synaptonemal
  • hr-mediated
  • dsb-induced
  • break-induced
  • end-joining
  • overhang
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
pinoresinol-lariciresinol reductase, pinoresinol/lariciresinol reductase, pinoresinol reductase, luplr2, plr-lc1, plr-lu2, (+)-pinoresinol/(+)-lariciresinol reductase, plr-la1, (+)-pinoresinol-(+)-lariciresinol reductase, rr-pinoresinol-rr-lariciresinol reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(+)-lariciresinol + NADP+ = (+)-pinoresinol + NADPH + H+
show the reaction diagram
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