Information on EC 18.104.22.168 - columbamine oxidasefor references in articles please use BRENDA:EC22.214.171.124
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An iron protein. Oxidation of the O-methoxyphenol structure forms the methylenedioxy group of berberine.
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The expected taxonomic range for this enzyme is: Berberis stolonifera
berberine synthase, EC 126.96.36.199, synthase, berberine, more
2 columbamine + O2 = 2 berberine + 2 H2O
oxidation of the O-methoxyphenol structure forms the methylenedioxy group of berberine
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