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EC Tree
IUBMB Comments The enzyme has been described from the bacteria Methylomonas sp. 16a and Bacillus indicus.
The enzyme appears in viruses and cellular organisms
Synonyms
4,4'-diapolycopene aldehyde oxidase, ALD, CrtN2, CrtNb,
crtNc ,
more
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4,4'-diapolycopene aldehyde oxidase
4,4'-diapolycopene aldehyde oxidase
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4,4'-diapolycopene aldehyde oxidase
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crtNc
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4,4'-diapolycopen-4-al + H2O + acceptor = 4,4'-diapolycopen-4-oate + reduced acceptor
(1)
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4,4'-diapolycopene-4,4'-dial + 2 H2O + 2 acceptor = 4,4'-diapolycopene-4,4'-dioate + 2 reduced acceptor
(2)
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4,4'-diapolycopen-4-al,donor:oxygen oxidoreductase (4,4'-diapolycopen-4-oate-forming)
The enzyme has been described from the bacteria Methylomonas sp. 16a and Bacillus indicus.
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4,4'-diapolycopen-4-al + H2O + acceptor
4,4'-diapolycopen-4-oate + reduced acceptor
4,4'-diapolycopene + H2O + acceptor
4,4'-diapolycopene-4,4'-dial + reduced acceptor
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?
4,4'-diapolycopene-4,4'-dial + H2O + acceptor
4,4'-diapolycopene-4,4'-dioate + reduced acceptor
4,4'-diaponeurosporen-4,4'-dial + acceptor
4,4'-diaponeurosporene-4,4'-dioic acid + reduced acceptor
4,4'-diaponeurosporen-4,4'-dial is a dark-reddish purple pigment
product is a pink pigment with absorption maxima at 465, 490, and 519 nm
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?
4,4'-diaponeurosporene + H2O + acceptor
4,4'-diaponeurosporen-4-al + reduced acceptor
high activity
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additional information
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the enzyme has moderate to low activity on neurosporene and lycopene and no activity on beta-carotene or zeta-carotene
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4,4'-diapolycopen-4-al + H2O + acceptor
4,4'-diapolycopen-4-oate + reduced acceptor
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?
4,4'-diapolycopen-4-al + H2O + acceptor
4,4'-diapolycopen-4-oate + reduced acceptor
-
-
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?
4,4'-diapolycopene-4,4'-dial + H2O + acceptor
4,4'-diapolycopene-4,4'-dioate + reduced acceptor
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-
-
?
4,4'-diapolycopene-4,4'-dial + H2O + acceptor
4,4'-diapolycopene-4,4'-dioate + reduced acceptor
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-
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?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
4,4'-diapolycopen-4-al + H2O + acceptor
4,4'-diapolycopen-4-oate + reduced acceptor
4,4'-diapolycopene-4,4'-dial + H2O + acceptor
4,4'-diapolycopene-4,4'-dioate + reduced acceptor
4,4'-diapolycopen-4-al + H2O + acceptor
4,4'-diapolycopen-4-oate + reduced acceptor
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-
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?
4,4'-diapolycopen-4-al + H2O + acceptor
4,4'-diapolycopen-4-oate + reduced acceptor
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-
-
?
4,4'-diapolycopene-4,4'-dial + H2O + acceptor
4,4'-diapolycopene-4,4'-dioate + reduced acceptor
-
-
-
?
4,4'-diapolycopene-4,4'-dial + H2O + acceptor
4,4'-diapolycopene-4,4'-dioate + reduced acceptor
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?
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UniProt
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UniProt
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UniProt
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UniProt
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physiological function
coexpression of the crtN ald crtNb gene cluster from Methylomonas sp. with Staphylococcus aureus crtM in Escherichia coli results in synthesis of 4,4'-diaponeurosporene-4,4'-dioic acid as a pink pigment
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CRTNC_CYTFI
453
0
50131
Swiss-Prot
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CRTNC_METID
491
0
54648
Swiss-Prot
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ALD_METSP
Methylomonas sp
530
0
58539
Swiss-Prot
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A0A7U7EM97_9PSED
467
0
50528
TrEMBL
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A0A6M4GTI5_9PROT
454
0
48795
TrEMBL
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A0A653NVS6_9BACI
491
0
55541
TrEMBL
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A0A653I300_9BACL
490
0
55451
TrEMBL
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A0A653P961_9BACI
500
0
55525
TrEMBL
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A0A653U3K6_9BACL
492
0
55964
TrEMBL
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CRTP_METSP
Methylomonas sp
497
1
55574
Swiss-Prot
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expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli BL21(DE3) cells
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Tao, L.; Schenzle, A.; Odom, J.; Cheng, Q.
Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde
Appl. Environ. Microbiol.
71
3294-3301
2005
Methylomonas sp. (Q4VKV0)
brenda
Tao, L.; Schenzle, A.; Odom, J.; Cheng, Q.
Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde
Appl. Environ. Microbiol.
71
3294-3301
2005
Methylomonas sp. 16a (Q4VKU9)
brenda
Steiger, S.; Perez-Fons, L.; Cutting, S.M.; Fraser, P.D.; Sandmann, G.
Annotation and functional assignment of the genes for the C30 carotenoid pathways from the genomes of two bacteria Bacillus indicus and Bacillus firmus
Microbiology
161
194-202
2015
Metabacillus indicus (P0DPE9), Metabacillus indicus, Cytobacillus firmus (P0DPF0), Cytobacillus firmus
brenda
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