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Information on EC 1.2.7.5 - aldehyde ferredoxin oxidoreductase

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IUBMB Comments
This is an oxygen-sensitive enzyme that contains tungsten-molybdopterin and iron-sulfur clusters. Catalyses the oxidation of aldehydes (including crotonaldehyde, acetaldehyde, formaldehyde and glyceraldehyde) to their corresponding acids. However, it does not oxidize glyceraldehyde 3-phosphate [see EC 1.2.7.6, glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)]. Can use ferredoxin or methylviologen but not NAD(P)+ as electron acceptor.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
aldehyde Fd oxidoreductase, aldehyde ferredoxin oxidoreductase, aldehyde oxidase (ferredoxin), aldehyde oxidoreductase, aldehyde: ferredoxin oxidoreductase, aldehyde:ferredoxin oxidoreductase, AOR, Aor1, Aor2, Aor3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
an aldehyde + H2O + 2 oxidized ferredoxin = a carboxylate + 2 H+ + 2 reduced ferredoxin
show the reaction diagram
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