show all | hide all No of entries

Information on EC - pyruvate synthase

for references in articles please use BRENDA:EC1.2.7.1
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
Contains thiamine diphosphate and [4Fe-4S] clusters. The enzyme also decarboxylates 2-oxobutyrate with lower efficiency, but shows no activity with 2-oxoglutarate. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity. For examples of other members of this family, see EC, 2-oxoglutarate synthase and EC, 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin).
Specify your search results
Select one or more organisms in this record:
Word Map
The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota
AP120, Ape2126/2128, bifunctional pyruvate decarboxylase/pyruvate ferredoxin oxidoreductase, OFOR, PFO, PFO A, PFOR, PforA, PFR, PFR1, more
pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+
show the reaction diagram
Select items on the left to see more content.