Disease on EC 1.2.3.1 - aldehyde oxidase
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DISEASE 
TITLE OF PUBLICATION
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Amyotrophic Lateral Sclerosis
Analysis of aldehyde oxidase and xanthine dehydrogenase/oxidase as possible candidate genes for autosomal recessive familial amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Inhibition of vertebrate aldehyde oxidase as a therapeutic treatment for cancer, obesity, aging and amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis
Selective localization of mouse aldehyde oxidase mRNA in the choroid plexus and motor neurons.
Carcinogenesis
DNA cleavage during ethanol metabolism: role of superoxide radicals and catalytic iron.
Carcinoma
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b5 Activity.
Carcinoma, Ehrlich Tumor
Synthesis and properties of 7-hydroxymethotrexate polyglutamyl derivatives in Ehrlich ascites tumor cells in vitro.
Carcinoma, Hepatocellular
Identification of aldehyde oxidase 1 and aldehyde oxidase homologue 1 as dioxin-inducible genes.
Carcinoma, Renal Cell
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b5 Activity.
Colorectal Neoplasms
Aldehyde oxidase 1 promoted the occurrence and development of colorectal cancer by up-regulation of expression of CD133.
Drug-Related Side Effects and Adverse Reactions
Significance of aldehyde oxidase during drug development: Effects on drug metabolism, pharmacokinetics, toxicity, and efficacy.
Fatty Liver
Alleviation of fatty liver in a rat model by enhancing N1-methylnicotinamide bioavailability through aldehyde oxidase inhibition.
Fatty Liver
Reduction of fatty liver in rats by nicotinamide via the regeneration of the methionine cycle and the inhibition of aldehyde oxidase.
Genetic Diseases, Inborn
Rescue of lethal molybdenum cofactor deficiency by a biosynthetic precursor from Escherichia coli.
Herpes Simplex
Human Aldehyde Oxidase 1-Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes.
Infections
Aldehyde oxidase (AO) in the root nodules of Lupinus albus and Medicago truncatula: identification of AO in meristematic and infection zones.
Infections
The involvement of ROS producing aldehyde oxidase in plant response to Tombusvirus infection.
Influenza, Human
Dietary Flavonoid Aglycones and Their Glycosides: Which Show Better Biological Significance?
Leukemia
An iminium ion metabolite hampers the production of the pharmacologically active metabolite of a multikinase inhibitor KW-2449 in primates: irreversible inhibition of aldehyde oxidase and covalent binding with endogenous proteins.
Liver Cirrhosis, Alcoholic
Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study.
Lung Injury
Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung.
Motor Neuron Disease
Selective localization of mouse aldehyde oxidase mRNA in the choroid plexus and motor neurons.
Neoplasms
Alteration in Gene Pair Correlations in Tryptophan Metabolism as a Hallmark in Cancer Diagnosis.
Neoplasms
An in vivo comparison of oral 5-iodo-2'-deoxyuridine and 5-iodo-2-pyrimidinone-2'-deoxyribose toxicity, pharmacokinetics, and DNA incorporation in athymic mouse tissues and the human colon cancer xenograft, HCT-116.
Neoplasms
Compound K, a ginsenoside metabolite, plays an antiinflammatory role in macrophages by targeting the AKT1-mediated signaling pathway.
Neoplasms
Cyclophosphamide potentiation and aldehyde oxidase inhibition by phosphorylated aldehydes and acetals.
Neoplasms
Expression and prognostic relevance of long noncoding RNAs CRNDE and AOX2P in adult acute myeloid leukemia.
Neoplasms
Inhibition of vertebrate aldehyde oxidase as a therapeutic treatment for cancer, obesity, aging and amyotrophic lateral sclerosis.
Neoplasms
Metabolism of methotrexate and gamma-tert-butyl methotrexate by human leukemic cells in culture and by hepatic aldehyde oxidase in vitro.
Neoplasms
Metabolism of retinol and retinoic acid in N-methyl-N-nitrosourea-induced mammary carcinomas in rats.
Neoplasms
Polyglutamylation of the dihydrofolate reductase inhibitor gamma-methylene-10-deazaaminopterin is not essential for antitumor activity.
Neoplasms
Synthesis and properties of 7-hydroxymethotrexate polyglutamyl derivatives in Ehrlich ascites tumor cells in vitro.
Nervous System Diseases
Prenatal diagnosis and carrier detection for molybdenum cofactor deficiency type A in northern Israel using polymorphic DNA markers.
Nervous System Diseases
The peak height ratio of S-sulfonated transthyretin and other oxidized isoforms as a marker for molybdenum cofactor deficiency, measured by electrospray ionization mass spectrometry.
Obesity
Inhibition of vertebrate aldehyde oxidase as a therapeutic treatment for cancer, obesity, aging and amyotrophic lateral sclerosis.
Ovarian Neoplasms
Meta-analysis based gene expression profiling reveals functional genes in ovarian cancer.
Thyroid Neoplasms
Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b5 Activity.
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