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The expected taxonomic range for this enzyme is: Levilactobacillus brevis
Synonyms
Lac-HAVN dehydrogenase,
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Lac-HAVN dehydrogenase
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Lac-HAVN dehydrogenase
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5'-hydroxyaverantin + NADP+ = (1'S)-5'-oxoaverantin + NADPH + H+
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5'-hydroxyaverantin:NADP+ oxidoreductase
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5'-hydroxyaverantin + NADP+
(1'S)-5'-oxoaverantin + NADPH + H+
additional information
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5'-hydroxyaverantin + NADP+
(1'S)-5'-oxoaverantin + NADPH + H+
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the enzyme catalyzes a reaction in aflatoxin biosynthesis
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5'-hydroxyaverantin + NADP+
(1'S)-5'-oxoaverantin + NADPH + H+
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a mixture of two diastereomers, (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
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5'-hydroxyaverantin + NADP+
(1'S)-5'-oxoaverantin + NADPH + H+
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the enzyme catalyzes a reaction in aflatoxin biosynthesis
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5'-hydroxyaverantin + NADP+
(1'S)-5'-oxoaverantin + NADPH + H+
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a mixture of two diastereomers, (1'S,5'R)-hydroxyaverantin and (1'S,5'S)-hydroxyaverantin
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additional information
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no activity with nidurufin, averantin, and 6-phenylhexal-1-ol
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additional information
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no activity with nidurufin, averantin, and 6-phenylhexal-1-ol
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5'-hydroxyaverantin + NADP+
(1'S)-5'-oxoaverantin + NADPH + H+
5'-hydroxyaverantin + NADP+
(1'S)-5'-oxoaverantin + NADPH + H+
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the enzyme catalyzes a reaction in aflatoxin biosynthesis
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5'-hydroxyaverantin + NADP+
(1'S)-5'-oxoaverantin + NADPH + H+
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the enzyme catalyzes a reaction in aflatoxin biosynthesis
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NADP+
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no activity with NAD+
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0.0426
5'-hydroxyaverantin
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pH 7.5, 37°C
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6.5 - 8.5
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pH 6.5: about 75% of maximal activity, pH 8.5: about 30% of maximal activity
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35 - 60
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35°C: about 65% of maximal activity, 60°C: about 30% of maximal activity
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brenda
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brenda
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25873
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x * 25873, calculated from sequence, TOF MS analysis
33000
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x * 33000, SDS-PAGE
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x * 33000, SDS-PAGE
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x * 25873, calculated from sequence, TOF MS analysis
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x * 33000, SDS-PAGE
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x * 25873, calculated from sequence, TOF MS analysis
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Sakuno, E.; Kameyama, M.; Nakajima, H.; Yabe, K.
Purification and gene cloning of a dehydrogenase from Lactobacillus brevis that catalyzes a reaction involved in aflatoxin biosynthesis
Biosci. Biotechnol. Biochem.
72
724-734
2008
Levilactobacillus brevis, Levilactobacillus brevis IFO 12005
brenda
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1.2.1.B8 5'-hydroxyaverantin dehydrogenase (NADP+)
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