Information on EC 1.2.1.51 - pyruvate dehydrogenase (NADP+)

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EC Tree
IUBMB Comments
The Euglena enzyme can also use FAD or methyl viologen as acceptor, more slowly. The enzyme is inhibited by oxygen.
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Word Map
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
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pyruvate
+
CoA
+
NADP+
=
acetyl-CoA
+
CO2
+
NADPH
+
H+
+
+
=
+
+
+
Synonyms
CpPNO, PDH, pyruvate dehydrogenase, pyruvate:NADP+ oxidoreductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
pyruvate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH
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