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This enzyme catalyses the last step in the bacterial biosynthetic pathway to queuosine, the modified guanosine base in the wobble position in tRNAs specific for Tyr, His, Asp or Asn.
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The enzyme appears in viruses and cellular organisms
queuosine34 in tRNA
epoxyqueuosine34 in tRNA
, oQ reductase, QueG
queuosine34 in tRNA + acceptor + H2O = epoxyqueuosine34 in tRNA + reduced acceptor
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