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Information on EC - nicotinate dehydrogenase (cytochrome)

for references in articles please use BRENDA:EC1.17.2.1
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IUBMB Comments
This two-component enzyme from Pseudomonas belongs to the family of xanthine dehydrogenases, but differs from most other members of this family. While most members contain an FAD cofactor, the large subunit of this enzyme contains three c-type cytochromes, enabling it to interact with the electron transfer chain, probably by delivering the electrons to a cytochrome oxidase. The small subunit contains a typical molybdopterin cytosine dinucleotide(MCD) cofactor and two [2Fe-2S] clusters .
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The expected taxonomic range for this enzyme is: Pseudomonas putida
ndhsl, more
nicotinate + a ferricytochrome + H2O = 6-hydroxynicotinate + a ferrocytochrome + 2 H+
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