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Information on EC - nicotinate dehydrogenase

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EC Tree
     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.1 With NAD+ or NADP+ as acceptor
       nicotinate dehydrogenase
IUBMB Comments
A flavoprotein containing non-heme iron. The enzyme is capable of acting on a variety of nicotinate analogues to varying degrees, including pyrazine-2-carboxylate, pyrazine 2,3-dicarboxylate, trigonelline and 6-methylnicotinate. The enzyme from Clostridium barkeri also possesses a catalytically essential, labile selenium that can be removed by reaction with cyanide.
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Word Map
The enzyme appears in viruses and cellular organisms
dehydrogenase, nicotinate, EC, NA hydroxylase, NAH, NahAB1B2, NDH, NdhL, NdhM, NdhS, nicotinate dehydrogenase, more
nicotinate + H2O + NADP+ = 6-hydroxynicotinate + NADPH + H+
show the reaction diagram
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