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Information on EC 1.14.99.50 - gamma-glutamyl hercynylcysteine S-oxide synthase

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IUBMB Comments
Requires Fe2+ for activity. The enzyme, found in bacteria, is specific for both hercynine and gamma-L-glutamyl-L-cysteine. It is part of the biosynthesis pathway of ergothioneine.
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Word Map
The expected taxonomic range for this enzyme is: Mycobacterium
Synonyms
sulfoxide synthase, 5-histidylcysteine sulfoxide synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
hercynine + gamma-L-glutamyl-L-cysteine + O2 = gamma-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O
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PATHWAY SOURCE
PATHWAYS
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