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Information on EC 1.14.99.1 - prostaglandin-endoperoxide synthase

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IUBMB Comments
This enzyme acts both as a dioxygenase and as a peroxidase.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
cox-2, cyclooxygenase, cyclooxygenase-2, cox-1, cyclooxygenase 2, pghs-2, cyclooxygenase-1, ptgs2, prostaglandin synthetase, pghs-1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
arachidonate + reduced acceptor + 2 O2 = prostaglandin H2 + acceptor + H2O
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