Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 1.14.20.3 - (5R)-carbapenem-3-carboxylate synthase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sleeman, M.C.; Smith, P.; Kellam, B.; Chhabra, S.R.; Bycroft, B.W.; Schofield, C.J.
Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC)
Chembiochem
5
879-882
2004
Pectobacterium carotovorum
Manually annotated by BRENDA team
Stapon, A.; Li, R.; Townsend, C.A.
Synthesis of (3S,5R)-carbapenam-3-carboxylic acid and its role in carbapenem biosynthesis and the stereoinversion problem
J. Am. Chem. Soc.
125
15746-15747
2003
Pectobacterium carotovorum
Manually annotated by BRENDA team
Stapon, A.; Li, R.; Townsend, C.A.
Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline
J. Am. Chem. Soc.
125
8486-8493
2003
Pectobacterium carotovorum
Manually annotated by BRENDA team
Topf, M.; Sandala, G.M.; Smith, D.M.; Schofield, C.J.; Easton, C.J.; Radom, L.
The unusual bifunctional catalysis of epimerization and desaturation by carbapenem synthase
J. Am. Chem. Soc.
126
9932-9933
2004
Pectobacterium carotovorum
Manually annotated by BRENDA team
Clifton, I.J.; Doan, L.X.; Sleeman, M.C.; Topf, M.; Suzuki, H.; Wilmouth, R.C.; Schofield, C.J.
Crystal structure of carbapenem synthase (CarC)
J. Biol. Chem.
278
20843-20850
2003
Pectobacterium carotovorum (Q9XB59)
Manually annotated by BRENDA team
Borowski, T.; Broclawik, E.; Schofield, C.J.; Siegbahn, P.E.
Epimerization and desaturation by carbapenem synthase (CarC). A hybrid DFT study
J. Comput. Chem.
27
740-748
2006
Pectobacterium carotovorum
Manually annotated by BRENDA team
McGowan, S.J.; Sebaihia, M.; Porter, L.E.; Stewart, G.S.; Williams, P.; Bycroft, B.W.; Salmond, G.P.
Analysis of bacterial carbapenem antibiotic production genes reveals a novel beta-lactam biosynthesis pathway
Mol. Microbiol.
22
415-426
1996
Pectobacterium carotovorum
Manually annotated by BRENDA team
Ma, G.; Zhu, W.; Su, H.; Cheng, N.; Liu, Y.
Uncoupled epimerization and desaturation by carbapenem synthase mechanistic insights from QM/MM studies
ACS Catal.
5
5556-5566
2015
Streptomyces cattleya
-
Manually annotated by BRENDA team
Chang, W.; Guo, Y.; Wang, C.; Butch, S.; Rosenzweig, A.; Boal, A.; Krebs, C.; Bollinger Jr., J.
Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics
Science
343
1140-1144
2014
Pectobacterium carotovorum subsp. carotovorum (Q9XB59)
Manually annotated by BRENDA team