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Information on EC 1.14.19.71 - fumitremorgin C synthase

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IUBMB Comments
A heme-thiolate protein (P-450). The protein from the fungus Aspergillus fumigatus also has activity with tryprostatin B forming demethoxyfumitremorgin C. Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgins and verruculogen.
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The expected taxonomic range for this enzyme is: Aspergillus fumigatus
Synonyms
ftmE, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
tryprostatin A + [reduced NADPH-hemoprotein reductase] + O2 = fumitremorgin C + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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