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Information on EC 1.14.19.15 - (11Z)-hexadec-11-enoyl-CoA conjugase

for references in articles please use BRENDA:EC1.14.19.15
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IUBMB Comments
The enzyme, characterized from the silk moth Bombyx mori, catalyses a step in the pathway for the biosynthesis of bombykol, a sex pheromone produced by the moth. The enzyme converts a single cis double bond at position 11 of (11Z)-hexadec-11-enoyl-CoA into conjugated 10 trans and 12 cis double bonds. Prior to catalysing this reaction, the enzyme catalyses the introduction of the cis bond in position 11 (cf. EC 1.14.19.5, acyl-CoA 11-desaturase).
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The expected taxonomic range for this enzyme is: Bombyx mori
Synonyms
Bmpgdesat1, desat1, PG Z11/DELTA10,12 desaturase, pgdesat1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(11Z)-hexadec-11-enoyl-CoA + reduced acceptor + O2 = (10E,12Z)-hexadeca-10,12-dienoyl-CoA + acceptor + 2 H2O
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PATHWAY SOURCE
PATHWAYS
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