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Information on EC 1.14.19.13 - acyl-CoA 15-desaturase

for references in articles please use BRENDA:EC1.14.19.13
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IUBMB Comments
The enzyme, characterized from the the plant Sorghum bicolor, is involved in the biosynthesis of sorgoleone, an allelopathic compound produced in root hair cells. The enzyme inserts a cis double bond at carbon 15. When acting on its natural substrate, (9Z,12Z)-hexadeca-9,12-dienoyl-CoA, it produces a product with a terminal double bond.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
fad3a, omega-3 desaturase, fad3-2, rkd12, cpfad2, csfad3a, csfad3, ehdes15, cpfad3, delta15 desaturase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(9Z,12Z)-hexadeca-9,12-dienoyl-CoA + reduced acceptor + O2 = (9Z,12Z,15Z)-hexadeca-9,12,15-trienoyl-CoA + acceptor + 2 H2O
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PATHWAY SOURCE
PATHWAYS
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