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Information on EC 1.14.15.8 - steroid 15beta-monooxygenase

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IUBMB Comments
The enzyme from the bacterium Bacillus megaterium hydroxylates a variety of 3-oxo-Delta4-steroids in position 15beta. Ring A-reduced, aromatic, and 3beta-hydroxy-Delta4-steroids do not serve as substrates .
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The expected taxonomic range for this enzyme is: Bacillus megaterium
Synonyms
15beta-hydroxylase, 15beta-hydroxylase CYP106A2, BmCYP106A2, Cyp106A1, CYP106A2, cytochrome P-450meg, cytochrome P450meg, steroid-15-beta-monooxygenase, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
progesterone + 2 reduced [2Fe-2S] ferredoxin + O2 = 15beta-hydroxyprogesterone + 2 oxidized [2Fe-2S] ferredoxin + H2O
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