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Information on EC 1.14.15.19 - C-19 steroid 1alpha-hydroxylase

for references in articles please use BRENDA:EC1.14.15.19
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IUBMB Comments
The enzyme, characterized from the bacterium Sorangium cellulosum, is a class I cytochrome P-450, and uses ferredoxin as its electron donor . It was shown to act on several C-19 steroid substrates, including testosterone, androstenedione, testosterone-acetate and 11-oxoandrostenedione .
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The expected taxonomic range for this enzyme is: Sorangium cellulosum
Reaction Schemes
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2
reduced ferredoxin [iron-sulfur] cluster
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2
=
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2
oxidized ferredoxin [iron-sulfur] cluster
Synonyms
cyp260a1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
testosterone + 2 reduced ferredoxin [iron-sulfur] cluster + O2 + 2 H+ = 1alpha-hydroxytestosterone + H2O + 2 oxidized ferredoxin [iron-sulfur] cluster
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