Reference on EC 1.14.15.16 - vitamin D3 24-hydroxylase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Astecker, N.; Bobrovnikova, E.A.; Omdahl, J.L.; Gennaro, L.; Vouros, P.; Schuster, I.; Uskokovic, M.R.; Ishizuka, S.; Wang, G.; Reddy, G.S.
C-25 hydroxylation of 1alpha,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1): metabolism studies with human keratinocytes and rat recombinant CYP24A1
Arch. Biochem. Biophys.
431
261-270
2004
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Kusudo, T.; Sakaki, T.; Abe, D.; Fujishima, T.; Kittaka, A.; Takayama, H.; Hatakeyama, S.; Ohta, M.; Inouye, K.
Metabolism of A-ring diastereomers of 1alpha,25-dihydroxyvitamin D3 by CYP24A1
Biochem. Biophys. Res. Commun.
321
774-782
2004
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Beckman, M.J.; Tadikonda, P.; Werner, E.; Prahl, J.; Yamada, S.; DeLuca, H.F.
Human 25-hydroxyvitamin D3-24-hydroxylase, a multicatalytic enzyme
Biochemistry
35
8465-8472
1996
Homo sapiens
Manually annotated by BRENDA team
Sawada, N.; Kusudo, T.; Sakaki, T.; Hatakeyama, S.; Hanada, M.; Abe, D.; Kamao, M.; Okano, T.; Ohta, M.; Inouye, K.
Novel metabolism of 1 alpha,25-dihydroxyvitamin D3 with C24-C25 bond cleavage catalyzed by human CYP24A1
Biochemistry
43
4530-4537
2004
Homo sapiens
Manually annotated by BRENDA team
Zhu, J.; Barycki, R.; Chiellini, G.; Deluca, H.F.
Screening of selective inhibitors of 1alpha,25-dihydroxyvitamin D3 24-hydroxylase using recombinant human enzyme expressed in Escherichia coli
Biochemistry
49
10403-10411
2010
Homo sapiens
Manually annotated by BRENDA team
Masuda, S.; Strugnell, S.A.; Knutson, J.C.; St-Arnaud, R.; Jones, G.
Evidence for the activation of 1alpha-hydroxyvitamin D2 by 25-hydroxyvitamin D-24-hydroxylase: Delineation of pathways involving 1alpha,24-dihydroxyvitamin D2 and 1alpha,25-dihydroxyvitamin D2
Biochim. Biophys. Acta
1761
221-234
2006
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Tenenhouse, H.S.; Jones, G.
Effect of the X-linked Hyp mutation and vitamin D status on induction of renal 25-hydroxyvitamin D3-24-hydroxylase
Endocrinology
120
609-616
1987
Mus musculus
Manually annotated by BRENDA team
Akeno, N.; Saikatsu, S.; Kawane, T.; Horiuchi, N.
Mouse vitamin D-24-hydroxylase: molecular cloning, tissue distribution, and transcriptional regulation by 1alpha,25-dihydroxyvitamin D3
Endocrinology
138
2233-2240
1997
Mus musculus
Manually annotated by BRENDA team
Sakaki, T.; Kagawa, N.; Yamamoto, K.; Inouye, K.
Metabolism of vitamin D3 by cytochromes P450
Front. Biosci.
10
119-134
2005
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Danan, J.L.; Delorme, A.C.; Mathieu, H.
Presence of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 24-hydroxylase in vitamin D target cells of rat yolk sac
J. Biol. Chem.
257
10715-10721
1982
Rattus norvegicus
Manually annotated by BRENDA team
Patel, S.R.; Ke, H.Q.; Hsu, C.H.
Effect of vitamin D metabolites on calcitriol degradative enzymes in renal failure
Kidney Int.
45
509-514
1994
Rattus norvegicus
Manually annotated by BRENDA team
Hamamoto, H.; Kusudo, T.; Urushino, N.; Masuno, H.; Yamamoto, K.; Yamada, S.; Kamakura, M.; Ohta, M.; Inouye, K.; Sakaki, T.
Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: amino acid residues responsible for species-based difference of CYP24A1 between humans and rats
Mol. Pharmacol.
70
120-128
2006
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Prosser, D.E.; Kaufmann, M.; OLeary, B.; Byford, V.; Jones, G.
Single A326G mutation converts human CYP24A1 from 25-OH-D3-24-hydroxylase into -23-hydroxylase, generating 1alpha,25-(OH)2D3-26,23-lactone
Proc. Natl. Acad. Sci. USA
104
12673-12678
2007
Homo sapiens
Manually annotated by BRENDA team
Prosser, D.E.; Jones, G.
Enzymes involved in the activation and inactivation of vitamin D
Trends Biochem. Sci.
29
664-673
2004
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Kaufmann, M.; Prosser, D.E.; Jones, G.
Bioengineering anabolic vitamin D-25-hydroxylase activity into the human vitamin D catabolic enzyme, cytochrome P450 CYP24A1, by a V391L mutation
J. Biol. Chem.
286
28729-28737
2011
Homo sapiens
Manually annotated by BRENDA team
Urbschat, A.; Paulus, P.; von Quernheim, Q.F.; Brueck, P.; Badenhoop, K.; Zeuzem, S.; Ramos-Lopez, E.
Vitamin D hydroxylases CYP2R1, CYP27B1 and CYP24A1 in renal cell carcinoma
Eur. J. Clin. Invest.
43
1282-1290
2013
Homo sapiens
Manually annotated by BRENDA team
Jones, G.; Prosser, D.E.; Kaufmann, M.
25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D
Arch. Biochem. Biophys.
523
9-18
2012
Rattus norvegicus
Manually annotated by BRENDA team
Luo, W.; Hershberger, P.A.; Trump, D.L.; Johnson, C.S.
24-Hydroxylase in cancer: impact on vitamin D-based anticancer therapeutics
J. Steroid Biochem. Mol. Biol.
136
252-257
2013
Homo sapiens
Manually annotated by BRENDA team
Hoebaus, J.; Fetahu, I.S.h.; Khorchide, M.; Manhardt, T.; Kallay, E.
Epigenetic regulation of the 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1) in colon cancer cells
J. Steroid Biochem. Mol. Biol.
136
296-299
2013
Homo sapiens
Manually annotated by BRENDA team
Ferla, S.; Gomaa, M.S.; Brancale, A.; Zhu, J.; Ochalek, J.T.; DeLuca, H.F.; Simons, C.
Novel styryl-indoles as small molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation
Eur. J. Med. Chem.
87
39-51
2014
Homo sapiens (Q07973)
Manually annotated by BRENDA team
Tieu, E.W.; Tang, E.K.; Tuckey, R.C.
Kinetic analysis of human CYP24A1 metabolism of vitamin D via the C24-oxidation pathway
FEBS J.
281
3280-3296
2014
Homo sapiens (Q07973), Rattus norvegicus (Q09128)
Manually annotated by BRENDA team
Rhieu, S.Y.; Annalora, A.J.; Wang, G.; Flarakos, C.C.; Gathungu, R.M.; Vouros, P.; Sigueeiro, R.; Mourino, A.; Schuster, I.; Palmore, G.T.; Reddy, G.S.
Metabolic stability of 3-epi-1alpha,25-dihydroxyvitamin D3 over 1alpha,25-dihydroxyvitamin D3: metabolism and molecular docking studies using rat CYP24A1
J. Cell. Biochem.
114
2293-2305
2013
Rattus norvegicus (Q09128)
Manually annotated by BRENDA team
Mugg, A.; Legeza, B.; Tee, M.K.; Damm, I.; Long, R.K.; Miller, W.L.
Quantitation of CYP24A1 enzymatic activity with a simple two-hybrid system
J. Clin. Endocrinol. Metab.
100
684-688
2015
Homo sapiens, Homo sapiens (Q07973)
Manually annotated by BRENDA team
Ferla, S.; Aboraia, A.S.; Brancale, A.; Pepper, C.J.; Zhu, J.; Ochalek, J.T.; DeLuca, H.F.; Simons, C.
Small-molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): synthesis and biological evaluation
J. Med. Chem.
57
7702-7715
2014
Homo sapiens (Q07973)
Manually annotated by BRENDA team
Hartfield, K.A.; Stout, C.D.; Annalora, A.J.
The novel purification and biochemical characterization of a reversible CYP24A1:adrenodoxin complex
J. Steroid Biochem. Mol. Biol.
136
47-53
2013
Rattus norvegicus
Manually annotated by BRENDA team