Information on EC 1.14.14.65 - sugiol synthase

for references in articles please use BRENDA:EC1.14.14.65
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The expected taxonomic range for this enzyme is: Salvia miltiorrhiza

EC NUMBER
COMMENTARY hide
1.14.14.65
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RECOMMENDED NAME
GeneOntology No.
sugiol synthase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ferruginol + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = sugiol + 2 [oxidized NADPH-hemoprotein reductase] + 3 H2O
show the reaction diagram
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Diterpenoid biosynthesis
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Biosynthesis of secondary metabolites
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SYSTEMATIC NAME
IUBMB Comments
ferruginol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (sugiol forming)
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
11-hydroxyferruginol + [reduced NADPH-hemoprotein reductase] + O2
11-hydroxysugiol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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?
ferruginol + [reduced NADPH-hemoprotein reductase] + O2
sugiol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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?
additional information
?
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enzyme addtionally oxidizes ferruginol at C-11 to give 11-hydroxyferruginol, reaction of EC 1.14.14.60
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
expression is more abundant in the root than in aerial tissues
Manually annotated by BRENDA team