Reference on EC 1.14.14.55 - quinine 3-monooxygenase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zhao, X.J.; Yokoyama, H.; Chiba, K.; Wanwimolruk, S.; Ishizaki, T.
Identification of human cytochrome P450 isoforms involved in the hydroxylation of quinine by human liver microsomes and nine recombinant human cytochromes P450
J. Pharmacol. Exp. Ther.
279
1327-1334
1996
Homo sapiens
Zhao, X.J.; Kawashiro, T.; Ishizaki, T.
Mutual inhibition between quinine and etoposide by human liver microsomes. Evidence for cytochrome P4503A4 involvement in their major metabolic pathways
Drug Metab. Dispos.
26
188-191
1997
Homo sapiens
Zhao, X.J.; Ishizaki, T.
The in vitro hepatic metabolism of quinine in mice, rats and dogs: comparison with human liver microsomes
J. Pharmacol. Exp. Ther.
283
1168-1176
1997
Canis lupus familiaris, Homo sapiens, Mus musculus, Rattus norvegicus
Relling, M.V.; Evans, R.; Dass, C.; Desiderio, D.M.; Nemec, J.
Human cytochrome P450 metabolism of teniposide and etoposide
J. Pharmacol. Exp. Ther.
261
491-496
1992
Homo sapiens
Mirghani, R.A.; Sayi, J.; Aklillu, E.; Allqvist, A.; Jande, M.; Wennerholm, A.; Eriksen, J.; Herben, V.M.; Jones, B.C.; Gustafsson, L.L.; Bertilsson, L.
CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population
Pharmacogenet. Genomics
16
637-645
2006
Homo sapiens
Allqvist, A.; Miura, J.; Bertilsson, L.; Mirghani, R.A.
Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers
Eur. J. Clin. Pharmacol.
63
173-179
2007
Homo sapiens
Wanwimolruk, S.; Wong, K.; Wanwimolruk, P.
Variable inhibitory effect of different brands of commercial herbal supplements on human cytochrome P-450 CYP3A4
Drug Metabol. Drug Interact.
24
17-35
2009
Homo sapiens (P08684), Homo sapiens
Diczfalusy, U.; Miura, J.; Roh, H.K.; Mirghani, R.A.; Sayi, J.; Larsson, H.; Bodin, K.G.; Allqvist, A.; Jande, M.; Kim, J.W.; Aklillu, E.; Gustafsson, L.L.; Bertilsson, L.
4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians
Pharmacogenet. Genomics
18
201-208
2008
Homo sapiens (P08684), Homo sapiens
Zhang, H.; Coville, P.F.; Walker, R.J.; Miners, J.O.; Birkett, D.J.; Wanwimolruk, S.
Evidence for involvement of human CYP3A in the 3-hydroxylation of quinine
Br. J. Clin. Pharmacol.
43
245-252
1997
Homo sapiens
Zhao, X.J.; Ishizaki, T.
Metabolic interactions of selected antimalarial and non-antimalarial drugs with the major pathway (3-hydroxylation) of quinine in human liver microsomes
Br. J. Clin. Pharmacol.
44
505-511
1997
Homo sapiens
Wanwimolruk, S.; Paine, M.F.; Pusek, S.N.; Watkins, P.B.
Is quinine a suitable probe to assess the hepatic drug-metabolizing enzyme CYP3A4?
Br. J. Clin. Pharmacol.
54
643-651
2002
Homo sapiens
Mirghani, R.A.; Hellgren, U.; Westerberg, P.A.; Ericsson, O.; Bertilsson, L.; Gustafsson, L.L.
The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine in vivo
Clin. Pharmacol. Ther.
66
454-460
1999
Homo sapiens
Numata, M.; Fawcett, J.P.; Rosengren, R.J.; Wanwimolruk, S.
Ontogeny of hepatic microsomal 3-hydroxylation of quinine in Adelie Penguins
Comp. Biochem. Physiol. C
138
53-58
2004
Pygoscelis adeliae
Mirghani, R.A.; Yasar, U.; Zheng, T.; Cook, J.M.; Gustafsson, L.L.; Tybring, G.; Ericsson, O.
Enzyme kinetics for the formation of 3-hydroxyquinine and three new metabolites of quinine in vitro; 3-hydroxylation by CYP3A4 is indeed the major metabolic pathway
Drug Metab. Dispos.
30
1368-1371
2002
Homo sapiens
Mirghani, R.A.; Ericsson, O.; Tybring, G.; Gustafsson, L.L.; Bertilsson, L.
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man
Eur. J. Clin. Pharmacol.
59
23-28
2003
Homo sapiens
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