Reference on EC 1.14.14.29 - 25/26-hydroxycholesterol 7alpha-hydroxylase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schwarz, M.; Lund, E.G.; Lathe, R.; Björkhem, I.; Russell, D.W.
Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA
J. Biol. Chem.
272
23995-24001
1997
Mus musculus
Manually annotated by BRENDA team
Russell, D.W.
The enzymes, regulation, and genetics of bile acid synthesis
Annu. Rev. Biochem.
72
137-174
2003
Homo sapiens (O75881), Mus musculus (Q60991)
Manually annotated by BRENDA team
Martin, C.; Bean, R.; Rose, K.; Habib, F.; Seckl, J.
cyp7b1 catalyses the 7alpha-hydroxylation of dehydroepiandrosterone and 25-hydroxycholesterol in rat prostate
Biochem. J.
355
509-515
2001
Rattus norvegicus
Manually annotated by BRENDA team
Toll, A.; Wikvall, K.; Sudjana-Sugiaman, E.; Kondo, K.H.; Björhem, I.
7alpha-Hydroxylation of 25-hydroxycholesterol in liver microsomes. Evidence that the enzyme involved is different from cholesterol 7alpha-hydoxylase
Eur. J. Biochem.
224
309-316
1994
Homo sapiens, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Wu, Z.; Chiang, J.Y.
Transcriptional regulation of human oxysterol 7alpha-hydroxylase gene (CYP7B1) by Sp1
Gene
272
191-197
2001
Homo sapiens
Manually annotated by BRENDA team
Pandak William, M.; Hylemon Phillip, B.; Ren, S.; Marques, D.; Gil, G.; Redford, K.; Mallonee, D.; Vlahcevic, Z.R.
Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes
Hepatology
35
1400-1408
2002
Rattus norvegicus
Manually annotated by BRENDA team
Li-Hawkins, J.; Lund, E.G.; Turley, S.D.; Russell, D.W.
Disruption of the oxysterol 7alpha-hydroxylase gene in mice
J. Biol. Chem.
275
16536-16542
2000
Mus musculus
Manually annotated by BRENDA team
Li-Hawkins, J.; Lund, E.G.; Bronson, A.D.; Russell, D.W.
Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol
J. Biol. Chem.
275
16543-16549
2000
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Wu, Z.; Martin, K.O.; Javitt, N.B.; Chiang, J.Y.
Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1
J. Lipid Res.
40
2195-2203
1999
Homo sapiens
Manually annotated by BRENDA team
Ren, S.; Marques, D.; Redford, K.; Hylemon, P.B.; Gil, G.; Vlahcevic, Z.R.; Pandak, W.M.
Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat
Metabolism
52
636-642
2003
Rattus norvegicus
Manually annotated by BRENDA team
Tsaousidou, M.K.; Ouahchi, K.; Warner, T.T.; Yang, Y.; Simpson, M.A.; Laing, N.G.; Wilkinson, P.A.; Madrid, R.E.; Patel, H.; Hentati, F.; Patton, M.A.; Hentati, A.; Lamont, P.J.; Siddique, T.; Crosby, A.H.
Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration
Am. J. Hum. Genet.
82
510-515
2008
Homo sapiens
Manually annotated by BRENDA team
Pettersson, H.; Holmberg, L.; Axelson, M.; Norlin, M.
CYP7B1-mediated metabolism of dehydroepiandrosterone and alpha-androstane-3beta,17beta-diol - potential role(s) for estrogen signaling
FEBS J.
275
1778-1789
2008
Homo sapiens, Sus scrofa
Manually annotated by BRENDA team
Hennebert, O.; Chalbot, S.; Alran, S.; Morfin, R.
Dehydroepiandrosterone 7alpha-hydroxylation in human tissues: possible interference with type 1 11beta-hydroxysteroid dehydrogenase-mediated processes
J. Steroid Biochem. Mol. Biol.
104
326-333
2007
Homo sapiens
Manually annotated by BRENDA team
Wada, T.; Kang, H.S.; Angers, M.; Gong, H.; Bhatia, S.; Khadem, S.; Ren, S.; Ellis, E.; Strom, S.C.; Jetten, A.M.; Xie, W.
Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3)
Mol. Pharmacol.
73
891-899
2008
Mus musculus
Manually annotated by BRENDA team
Olsson, M.; Gustafsson, O.; Skogastierna, C.; Tolf, A.; Rietz, B.D.; Morfin, R.; Rane, A.; Ekstroem, L.
Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma
Prostate
67
1439-1446
2007
Homo sapiens
Manually annotated by BRENDA team
Burke, K.T.; Horn, P.S.; Tso, P.; Heubi, J.E.; Woollett, L.A.
Hepatic bile acid metabolism in the neonatal hamster: expansion of the bile acid pool parallels increased Cyp7a1 expression levels
Am. J. Physiol. Gastrointest. Liver Physiol.
297
G144-G151
2009
Mesocricetus auratus
Manually annotated by BRENDA team
Diczfalusy, U.; Olofsson, K.; Carlsson, A.; Gong, M.; Golenbock, D.; Rooyackers, O.; Fläring, U.; Björkbacka, H.
Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide
J. Lipid Res.
50
2258-2264
2009
Mus musculus
Manually annotated by BRENDA team
Pettersson, H.; Lundqvist, J.; Oliw, E.; Norlin, M.
CYP7B1-mediated metabolism of 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol): A novel pathway for potential regulation of the cellular levels of androgens and neurosteroids
Biochim. Biophys. Acta
1791
1206-1215
2009
Homo sapiens, Homo sapiens (O75881), Mus musculus (Q60991), Sus scrofa
Manually annotated by BRENDA team
Zhou, C.; King, N.; Chen, K.Y.; Breslow, J.L.
Activation of pregnane X receptor induces hypercholesterolemia in wild-type and accelerates atherosclerosis in apolipoprotein E deficient mice
J. Lipid Res.
50
2004-2010
2009
Mus musculus
Manually annotated by BRENDA team
Tang, W.; Pettersson, H.; Norlin, M.
Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling
J. Steroid Biochem. Mol. Biol.
112
63-73
2008
Homo sapiens
Manually annotated by BRENDA team
Arnoldi, A.; Crimella, C.; Tenderini, E.; Martinuzzi, A.; D'Angelo, M.G.; Musumeci, O.; Toscano, A.; Scarlato, M.; Fantin, M.; Bresolin, N.; Bassi, M.T.
Clinical phenotype variability in patients with hereditary spastic paraplegia type 5 associated with CYP7B1 mutations
Clin. Genet.
81
150-157
2012
Homo sapiens, Homo sapiens (O75881)
Manually annotated by BRENDA team
Roos, P.; Svenstrup, K.; Danielsen, E.R.; Thomsen, C.; Nielsen, J.E.
CYP7B1: novel mutations and magnetic resonance spectroscopy abnormalities in hereditary spastic paraplegia type 5A
Acta Neurol. Scand.
129
330-334
2013
Homo sapiens
Manually annotated by BRENDA team
Siam, A.; Brancale, A.; Simons, C.
Comparative modeling of 25-hydroxycholesterol-7alpha-hydroxylase (CYP7B1): ligand binding and analysis of hereditary spastic paraplegia type 5 CYP7B1 mutations
J. Mol. Model.
18
441-453
2012
Homo sapiens, Homo sapiens (O75881)
Manually annotated by BRENDA team