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Information on EC 1.14.14.167 - (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase

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IUBMB Comments
This cytochrome P-450 (heme-thiolate) enzyme, characterized from the plant Papaver somniferum (opium poppy), participates in the biosynthesis of the isoquinoline alkaloid noscapine.
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The expected taxonomic range for this enzyme is: Papaver somniferum
Synonyms
1-hydroxy-13-O-acetyl-N-methylcanadine 8-hydroxylase, CYP82X1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + [reduced NADPH-hemoprotein reductase] + O2 = (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + [oxidized NADPH-hemoprotein reductase] + H2O
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