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Information on EC 1.14.13.25 - methane monooxygenase (soluble)

for references in articles please use BRENDA:EC1.14.13.25
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IUBMB Comments
The enzyme is soluble, in contrast to the particulate enzyme, EC 1.14.18.3. Broad specificity; many alkanes can be hydroxylated, and alkenes are converted into the corresponding epoxides; CO is oxidized to CO2, ammonia is oxidized to hydroxylamine, and some aromatic compounds and cyclic alkanes can also be hydroxylated, but more slowly.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
particulate methane monooxygenase, soluble methane monooxygenase, methane mono-oxygenase, methane monooxygenase hydroxylase, soluble methane monooxygenase hydroxylase, methane hydroxylase, cytoplasmic methane monooxygenase, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O
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