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Information on EC 1.14.13.195 - L-ornithine N5-monooxygenase (NADPH)

for references in articles please use BRENDA:EC1.14.13.195
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IUBMB Comments
A flavoprotein (FAD). The enzyme is involved in biosynthesis of N5-hydroxy-L-ornithine, N5-formyl-N5-hydroxy-L-ornithine or N5-acetyl-N5-hydroxy-L-ornithine. These nonproteinogenic amino acids are building blocks of siderophores produced by some bacteria (e.g. Streptomyces coelicolor, Saccharopolyspora erythraea and Pseudomonas aeruginosa). The enzyme is specific for NADPH. cf. EC 1.14.13.196, L-ornithine N5-monooxygenase [NAD(P)H].
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
siderophore a, l-orn n5-oxygenase, af-omo, ornithine hydroxylase, monooxygenase etcb, l-ornithine-ndelta-oxygenase, ornithine n5-monooxygenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-ornithine + NADPH + H+ + O2 = N5-hydroxy-L-ornithine + NADP+ + H2O
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PATHWAY SOURCE
PATHWAYS
BRENDA
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