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Information on EC 1.14.13.190 - ferruginol synthase

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IUBMB Comments
The enzyme is found in some members of the Lamiaceae (mint family). The enzyme from Rosmarinus officinalis (rosemary) is involved in biosynthesis of carnosic acid, while the enzyme from the Chinese medicinal herb Salvia miltiorrhiza is involved in the biosynthesis of the tanshinones, abietane-type norditerpenoid naphthoquinones that are the main lipophilic bioactive components found in the plant.
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The enzyme appears in viruses and cellular organisms
Synonyms
CYP76AH1, Cyp76AH22, Cyp76AH23, CYP76AH24, CYP76AH4, miltiradiene oxidase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
abieta-8,11,13-triene + NADPH + H+ + O2 = ferruginol + NADP+ + H2O
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