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Information on EC 1.14.13.182 - 2-heptyl-3-hydroxy-4(1H)-quinolone synthase

for references in articles please use BRENDA:EC1.14.13.182

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IUBMB Comments

The enzyme from the bacterium Pseudomonas aeruginosa catalyses the terminal step in biosynthesis of the signal molecule 2-heptyl-3,4-dihydroxyquinoline that plays a role in regulation of virulence genes.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
2-heptyl-3,4-dihydroxyquinoline synthase, Aqm, PqsH, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-heptyl-4(1H)-quinolone + NADH + H+ + O2 = 2-heptyl-3-hydroxy-4(1H)-quinolone + NAD+ + H2O
show the reaction diagram
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