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Information on EC - costunolide synthase

for references in articles please use BRENDA:EC1.14.13.120

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transferred to EC
IUBMB Comments

A heme-thiolate protein (P-450). The enzyme hydroxylates carbon C-6 of germacra-1(10),4,11(13)-trien-12-oate to give 6α-hydroxygermacra-1(10),4,11(13)-trien-12-oate, which probably spontaneously cyclises to form the lactone ring.

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