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Information on EC 1.14.13.107 - limonene 1,2-monooxygenase

for references in articles please use BRENDA:EC1.14.13.107

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IUBMB Comments

A flavoprotein (FAD). Limonene is the most widespread terpene and is formed by more than 300 plants. Rhodococcus erythropolis DCL14, a Gram-positive bacterium, is able to grow on both (S)-limonene and (R)-limonene as the sole source of carbon and energy. NADPH can act instead of NADH, although more slowly. It has not been established if the product formed is optically pure or a mixture of two enantiomers.

The expected taxonomic range for this enzyme is: Bacteria, Archaea
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-limonene + NAD(P)H + H+ + O2 = 1,2-epoxymenth-8-ene + NAD(P)+ + H2O
show the reaction diagram
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(S)-limonene + NAD(P)H + H+ + O2 = 1,2-epoxymenth-8-ene + NAD(P)+ + H2O
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
limonene degradation I (D-limonene), limonene degradation II (L-limonene)
Highest Expressing Human Cell Lines
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