Information on EC 1.14.13.104 - (+)-menthofuran synthase

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The expected taxonomic range for this enzyme is: Mentha x piperita

EC NUMBER
COMMENTARY hide
1.14.13.104
transferred to EC 1.14.14.143
RECOMMENDED NAME
GeneOntology No.
(+)-menthofuran synthase
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Monoterpenoid biosynthesis
-
-
Biosynthesis of secondary metabolites
-
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
no activity in Mentha arvensis cv. Kosi
-
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
-
the enzyme is involved in the terpene biosynthesis pathway, overview
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(+)-pulegone + NADPH + O2
(+)-menthofuran + NADP+ + H2O
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(+)-pulegone + NADPH + O2
(+)-menthofuran + NADP+ + H2O
show the reaction diagram
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mn2+
induces the enzyme pathway
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
real-time PCR-based transcript profiling of key terpenoid pathway genes, i.e. menthofuran synthase, pulegone reductase and menthol dehydrogenase, correlated with the menthofuran-rich phenotype in var. CIMAP-Patra
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semi-quantitative RT-PCR enzyme expressioon analysis
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
Mn2+ induces the enzyme pathway, the expression level of Mfs is significantly higher in the leaves of the 0.04 mM-treated plants than the control and other treatments groups, transcriptome analysis, detailed overview
ENGINEERING
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
-
hybrid cross-breading of menthofuran-rich Mentha piperita cv. Kukrail with Mentha arvensis cv. Kosi, which does not produce menthofuran, leads to plants with altered oil quality, chemoprofiling of essential oil, altered phenotype of genotype CIMAP-Patra, overview