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Information on EC 1.14.12.16 - 2-Hydroxyquinoline 5,6-dioxygenase

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IUBMB Comments
3-Methylquinolin-2-ol, quinolin-8-ol and quinolin-2,8-diol are also substrates. Quinolin-2-ols exist largely as their quinolin-2(1H)-one tautomers
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The expected taxonomic range for this enzyme is: Comamonas testosteroni
Synonyms
2-Hydroxyquinoline 5,6-dioxygenase, 2-oxo-1,2-dihydroquinoline 5,6-dioxygenase, Oxygenase, 2(1H)-quinolinone 5,6-di-, Quinolin-2(1H)-one 5,6-dioxygenase, Quinolin-2-ol 5,6-dioxygenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+
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PATHWAY SOURCE
PATHWAYS
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