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Information on EC 1.14.11.9 - flavanone 3-dioxygenase

for references in articles please use BRENDA:EC1.14.11.9

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IUBMB Comments

Requires Fe2+ and ascorbate. This plant enzyme catalyses an early step in the flavonoid biosynthesis pathway, leading to the production of flavanols and anthocyanins. Substrates include (2S)-naringenin, (2S)-eriodictyol, (2S)-dihydrotricetin and (2S)-pinocembrin. Some enzymes are bifuctional and also catalyse EC 1.14.20.6, flavonol synthase.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
flavanone 3-hydroxylase, flavanone-3-hydroxylase, flavanone 3beta-hydroxylase, csf3h, lcf3h, aaf3h, ctf3h, naringenin 3-dioxygenase, acf3h, (2s)-flavanone 3-hydroxylase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a (2S)-flavan-4-one + 2-oxoglutarate + O2 = a (2R,3R)-dihydroflavonol + succinate + CO2
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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