Reference on EC 1.14.11.8 - trimethyllysine dioxygenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hulse, J.D.; Ellis, S.R.; Henderson, L.M.
Carnitine biosynthesis. beta-Hydroxylation of trimethyllysine by an alpha-ketoglutarate-dependent mitochondrial dioxygenase
J. Biol. Chem.
253
1654-1659
1978
Rattus norvegicus
Manually annotated by BRENDA team
Henderson, L.M.; Nelson, P.J.; Henderson, L.
Mammalian enzymes of trimethyllysine conversion to trimethylaminobutyrate
Fed. Proc.
41
2843-2847
1982
Bos taurus
Manually annotated by BRENDA team
Sachan, D.S.; Hoppel, C.L.
Carnitine biosynthesis. Hydroxylation of N6-trimethyl-lysine to 3-hydroxy-N6-trimethyl-lysine
Biochem. J.
188
529-534
1980
Rattus norvegicus
Manually annotated by BRENDA team
Sachan, D.S.; Broquist, H.P.
Synthesis of carnitine from epsilon-N-trimethyllysine in post mitochondrial fractions of Neurospora crassa
Biochem. Biophys. Res. Commun.
96
870-875
1980
Neurospora crassa
Manually annotated by BRENDA team
Swiegers, J.H.; Vaz, F.M.; Pretorius, I.S.; Wanders, R.J.A.; Bauer, F.F.
Carnitine biosynthesis in neurospora crassa: identification of a cDNA coding for epsilon-N-trimethyllysine hydroxylase and its functional expression in Saccharomyces cerevisiae
FEMS Microbiol. Lett.
210
19-23
2002
Neurospora crassa
Manually annotated by BRENDA team
Vaz, F.M.; Ofman, R.; Westinga, K.; Back, J.W.; Wanders, R.J.A.
Molecular and biochemical characterization of rat epsilon-N-trimethyllysine hydroxylase, the first enzyme of carnitine biosynthesis
J. Biol. Chem.
276
33512-33517
2001
Homo sapiens, Homo sapiens (Q9NVH6), Mus musculus, Mus musculus (Q91ZE0), Rattus norvegicus (Q91ZW6)
Manually annotated by BRENDA team
van Vlies, N.; Wanders, R.J.; Vaz, F.M.
Measurement of carnitine biosynthesis enzyme activities by tandem mass spectrometry: differences between the mouse and the rat
Anal. Biochem.
354
132-139
2006
Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Monfregola, J.; Cevenini, A.; Terracciano, A.; van Vlies, N.; Arbucci, S.; Wanders, R.J.; DUrso, M.; Vaz, F.M.; Ursini, M.V.
Functional analysis of TMLH variants and definition of domains required for catalytic activity and mitochondrial targeting
J. Cell. Physiol.
204
839-847
2005
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Davis, A.T.; Monroe, T.J.
Carnitine deficiency and supplementation do not affect the gene expression of carnitine biosynthetic enzymes in rats
J. Nutr.
135
761-764
2005
Rattus norvegicus
Manually annotated by BRENDA team
van Vlies, N.; Ofman, R.; Wanders, R.J.; Vaz, F.M.
Submitochondrial localization of 6-N-trimethyllysine dioxygenase - implications for carnitine biosynthesis
FEBS J.
274
5845-5851
2007
Rattus norvegicus
Manually annotated by BRENDA team
Furusawa, H.; Sato, Y.; Tanaka, Y.; Inai, Y.; Amano, A.; Iwama, M.; Kondo, Y.; Handa, S.; Murata, A.; Nishikimi, M.; Goto, S.; Maruyama, N.; Takahashi, R.; Ishigami, A.
Vitamin C is not essential for carnitine biosynthesis in vivo: verification in vitamin C-depleted senescence marker protein-30/gluconolactonase knockout mice
Biol. Pharm. Bull.
31
1673-1679
2008
Mus musculus (Q91ZE0)
Manually annotated by BRENDA team
Fischer, M.; Hirche, F.; Kluge, H.; Eder, K.
A moderate excess of dietary lysine lowers plasma and tissue carnitine concentrations in pigs
Br. J. Nutr.
101
190-196
2009
Sus scrofa
Manually annotated by BRENDA team
Al Temimi, A.H.; Pieters, B.J.; Reddy, Y.V.; White, P.B.; Mecinovic, J.
Substrate scope for trimethyllysine hydroxylase catalysis
Chem. Commun. (Camb.)
52
12849-12852
2016
Homo sapiens, Homo sapiens (Q9NVH6)
Manually annotated by BRENDA team
Lesniak, R.; Markolovic, S.; Tars, K.; Schofield, C.
Human carnitine biosynthesis proceeds via (2S,3S)-3-hydroxy-Nepsilon-trimethyllysine
Chem. Commun. (Camb.)
53
440-442
2017
Homo sapiens (Q9NVH6)
Manually annotated by BRENDA team
Vijayendar Reddy, Y.; Al Temimi, A.H.; Mecinovic, J.
Fluorinated trimethyllysine as a (19)F NMR probe for trimethyllysine hydroxylase catalysis
Org. Biomol. Chem.
15
1350-1354
2017
Homo sapiens (Q9NVH6)
Manually annotated by BRENDA team
Reddy, Y.V.; Al Temimi, A.H.; White, P.B.; Mecinovi?, J.
Evidence that trimethyllysine hydroxylase catalyzes the formation of (2S,3S)-3-hydroxy-N(epsilon)-trimethyllysine
Org. Lett.
19
400-403
2017
Homo sapiens, Homo sapiens (Q9NVH6)
Manually annotated by BRENDA team
Kazaks, A.; Makrecka-Kuka, M.; Kuka, J.; Voronkova, T.; Akopjana, I.; Grinberga, S.; Pugovics, O.; Tars, K.
Expression and purification of active, stabilized trimethyllysine hydroxylase
Protein Expr. Purif.
104
1-6
2014
Homo sapiens (Q9NVH6)
Manually annotated by BRENDA team