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Information on EC 1.14.11.72 - [2-(trimethylamino)ethyl]phosphonate dioxygenase

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IUBMB Comments
Requires Fe2+ and ascorbate. The enzyme, found in bacteria, participates in a degradation pathway for [2-(trimethylamino)ethyl]phosphonate.
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The expected taxonomic range for this enzyme is: Leisingera caerulea
Reaction Schemes
[2-(trimethylamino)ethyl]phosphonate
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=
[(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate
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Synonyms
gamma-butyrobetaine hydroxylase, tmpA, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
[2-(trimethylamino)ethyl]phosphonate + 2-oxoglutarate + O2 = [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + succinate + CO2
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PATHWAY SOURCE
PATHWAYS
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