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Disease on EC 1.14.11.65 - [histone H3]-dimethyl-L-lysine9 demethylase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abducens Nerve Diseases
Sphenoid mucocele: an uncommon complication of a rare condition.
Abscess
A comparison of comedonal and skin surface lipids from hairless dogs showing clinical signs of acne.
Factors Affecting the Welfare of Unweaned Dairy Calves Destined for Early Slaughter and Abattoir Animal-Based Indicators Reflecting Their Welfare On-Farm.
Acne Vulgaris
A comparison of comedonal and skin surface lipids from hairless dogs showing clinical signs of acne.
Photocarcinogenesis and toxicity of benzoyl peroxide in hairless mice after simulated solar radiation.
Spontaneous comedones on the skin of hairless descendants of Mexican hairless dogs.
Adenocarcinoma
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance.
Specificity of epidermal chalone extracts for human epidermoid tumour cells in vitro: a preliminary report.
Adenoma
Trilogy Revisited: A Case Report of Co-Existing Nevus Sebaceous with Syringocystadenoma Papilliferum and Tubular Apocrine Adenoma.
Alopecia
A frameshift insertion in SGK3 leads to recessive hairlessness in Scottish Deerhounds: a candidate gene for human alopecia conditions.
A new allele of the mouse hairless gene interferes with Hox/LacZ transgene regulation in hair follicle primordia.
A newly identified missense mutation of the HR gene is associated with a novel, unusual phenotype of Marie Unna Hereditary Hypotrichosis 1 including limb deformities.
A novel homozygous variant in the dsp gene underlies the first case of non-syndromic form of alopecia.
A novel missense mutation in the mouse hairless gene causes irreversible hair loss: genetic and molecular analyses of Hr m1Enu.
Alopecia universalis associated with a mutation in the human hairless gene.
Androgenetic alopecia in heterozygous carriers of a mutation in the human hairless gene.
Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene.
Atrichia with papular lesions maps to 8p in the region containing the human hairless gene.
Atrichia with papular lesions resulting from a nonsense mutation within the human hairless gene.
Atrichia with papular lesions resulting from compound heterozygous mutations in the hairless gene: A lesson for differential diagnosis of alopecia universalis.
Atrichia with papular lesions resulting from novel compound heterozygous mutations in the human hairless gene.
Caspase-14 overexpression in hairless mice is not involved in utricle formation.
Characterization of hairless (Hr) and FGF5 genes provides insights into the molecular basis of hair loss in cetaceans.
Clinical and molecular diagnostic criteria of congenital atrichia with papular lesions.
Cloning, genomic organization, alternative transcripts and mutational analysis of the gene responsible for autosomal recessive universal congenital alopecia.
Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis.
Dermoscopic approach to a small round to oval hairless patch on the scalp.
Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice.
Encephalocraniocutaneous lipomatosis accompanied by the formation of bone cysts: Harboring clues to pathogenesis?
Evidence for pseudodominant inheritance of atrichia with papular lesions.
Evidence of hair loss after subacute exposure to 2-chloroethyl ethyl sulfide, a mustard analog, and beneficial effects of N-acetyl cysteine.
Experimental infection of red foxes (Vulpes vulpes) with Sarcoptes scabiei var. vulpes.
Folliculitis Decalvans and Lichen Planopilaris Phenotypic Spectrum-A Series of 7 New Cases With Focus on Histopathology.
Functional analysis of splice site mutations in the human hairless (HR) gene using a minigene assay.
Hair loss and cyst formation in hairless and rhino mutant mice.
Hairless and NFkappaB Form a Positive Feedback Loop After UVB and TNFalpha Stimulation(†).
Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis.
Hairless controls hair fate decision via Wnt/?-catenin signaling.
Hairless Gene Nonsense Mutations in Alopecia Universalis: A Case Report.
Identification of a genetic defect in the hairless gene in atrichia with papular lesions: evidence for phenotypic heterogeneity among inherited atrichias.
Identification of a new mutation in the gene coding for hairless protein responsible for alopecia universalis: The importance of direct gene sequencing.
Identification of a novel splice site mutation in the human hairless gene underlying atrichia with papular lesions.
Identification of a recurrent mutation in the human hairless gene underlying atrichia with papular lesions.
Identification of a recurrent nonsense mutation in HR gene responsible for atrichia with papular lesions in two Kashmiri families.
Induction of hair regrowth in the alopecia site of IFN-gamma knockout mice by allografting and IFN-gamma injection into the transplantation site.
Interactions of the vitamin D receptor with the corepressor hairless: analysis of hairless mutants in atrichia with papular lesions.
JmjC: cupin metalloenzyme-like domains in jumonji, hairless and phospholipase A2beta.
Ligand-independent actions of the vitamin D receptor maintain hair follicle homeostasis.
Ligand-independent regulation of the hairless promoter by vitamin D receptor.
Modulation of Vitamin D Receptor Activity by the Corepressor Hairless: Differential Effects of Hairless Isoforms.
Molecular basis for hair loss in mice carrying a novel nonsense mutation (Hrrh-R ) in the hairless gene (Hr).
Molecular basis for the rhino (hrrh-8J) phenotype: a nonsense mutation in the mouse hairless gene.
Molecular basis of congenital atrichia in humans and mice.
Morphological analysis of hair in the hr-2 mutant deer mouse (Peromyscus maniculatus).
Occurrence of dermatomycosis (ringworm) due to Trichophyton verrucosum in dairy calves and its spread to animal attendants.
Of hairless mice and men: the genetic basis of congenital alopecia universalis/congenital atrichia.
Photoletter to the editor: Congenital atrichia associated with an uncommon mutation of HR gene.
Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling.
Piccardi-Lassueur-Graham-Little syndrome associated with frontal fibrosing alopecia.
Protein kinase C is involved in the regulation of hairless mRNA expression during mouse keratinocyte differentiation.
SYNTHESIS OF INOSITOL IN MICE.
The co-repressor hairless has a role in epithelial cell differentiation in the skin.
The hairless gene in androgenetic alopecia: results of a systematic mutation screening and a family-based association approach.
The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor.
The hairless gene of the mouse: relationship of phenotypic effects with expression profile and genotype.
The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active.
Total hypotrichosis: genetic form of alopecia not linked to hairless gene.
Towards defining the pathogenesis of the hairless phenotype.
[Drug treatment of alopecia].
[Gene angora as a modifier of the mouse hairless gene]
[Inherited alopecia X in Pomeranians]
[Syringolymphoid hyperplasia with alopecia]
[The mouse hairless gene: its function in hair root and at the heart of a subtle pleiotropy]
[The we gene is a modifier of the wal gene in mice]
Alopecia Areata
Capillary electrophoretic profiling of rat hair: a tool for alopecia areata diagnosis.
Diagnosing and treating hair loss.
Mathematical model for alopecia areata.
Trichoscopy as a useful method to differentiate tinea capitis from alopecia areata in children at Zagazig University Hospitals.
[Drug treatment of alopecia].
Alzheimer Disease
Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations.
Anaphylaxis
In vivo suppression and enhancement of the murine homocytotropic antibody response by staphylococcal enterotoxin A.
Anemia, Hypochromic
An insertional mutagenesis system for analyzing the Chinese cabbage genome using Agrobacterium T-DNA.
Anthrax
Experimental cutaneous Bacillus anthracis infections in hairless HRS/J mice.
Resistance of athymic nude mice to experimental cutaneous Bacillus anthracis infection.
Arrhythmias, Cardiac
[Cardiac arrhythmia and hairless patient]
Arthralgia
[The anti-synthetase syndrome]
Arthritis
Factors Affecting the Welfare of Unweaned Dairy Calves Destined for Early Slaughter and Abattoir Animal-Based Indicators Reflecting Their Welfare On-Farm.
Arthritis, Rheumatoid
MicroRNA-137-mediated inhibition of lysine-specific demethylase-1 prevents against rheumatoid arthritis in an association with the REST/mTOR axis.
Ascorbic Acid Deficiency
Ascorbic acid deficiency leads to epidermal atrophy and UVB-induced skin pigmentation in SMP30/GNL knockout hairless mice.
Ataxia
Overt Infection with Chronic Bee Paralysis Virus (CBPV) in Two Honey Bee Colonies.
Atherosclerosis
MicroRNA-325 facilitates atherosclerosis progression by mediating the SREBF1/LXR axis via KDM1A.
SNF5 promotes IL-1? expression via H3K4me1 in atherosclerosis induced by homocysteine.
Autoimmune Diseases
Mathematical model for alopecia areata.
[Drug treatment of alopecia].
Basal Cell Nevus Syndrome
Complete spontaneous regression of multiple basal cell carcinomas in the basal cell nevus syndrome: the possible role of transepithelial elimination.
Blister
A skin suction blister model in hairless rats: application to the study of anti-inflammatory and immunomodulatory drugs.
Evaluation of neutralized chemical agent identification sets (CAIS) for skin injury with an overview of the vesicant potential of agent degradation products.
Evaluation of the effect of heparin and tetracycline on the cohesion of the dermal-epidermal junction.
Nature of skin fragility in patients receiving retinoids for systemic effect.
Brain Neoplasms
Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours.
MiR-137-3p Inhibits Colorectal Cancer Cell Migration by Regulating a KDM1A-Dependent Epithelial-Mesenchymal Transition.
Breast Neoplasms
Control of Breast Cancer Pathogenesis by Histone Methylation and the Hairless Histone Demethylase.
High KDM1A Expression Associated with Decreased CD8+T Cells Reduces the Breast Cancer Survival Rate in Patients with Breast Cancer.
Histone demethylase KDM7A is required for stem cell maintenance and apoptosis inhibition in breast cancer.
Inhibition of Histone Demethylases LSD1 and UTX Regulates ER? Signaling in Breast Cancer.
KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer.
Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ER?-dependent and -independent manners.
ORY-1001, a KDM1A inhibitor, inhibits proliferation, and promotes apoptosis of triple negative breast cancer cells by inactivating androgen receptor.
The Histone Demethylase Enzymes KDM3A and KDM4B Co-Operatively Regulate Chromatin Transactions of the Estrogen Receptor in Breast Cancer.
The Jumonji Domain-Containing Histone Demethylase Homolog 1D/lysine Demethylase 7A (JHDM1D/KDM7A) Is an Epigenetic Activator of RHOJ Transcription in Breast Cancer Cells.
The ZNF750-RAC1 axis as potential prognostic factor for breast cancer.
[Function of histone demethylasehistone lysine-specific demethylase 1A in tumor initiation and progression].
[Knockdown of lysine-specific demethylase 3A (KDM3A) inhibits the invasion and migration of MDA-MB-231 breast cancer cells and arrests the cell cycle in the G0/G1 phase].
Bursitis
Assessment of welfare of finishing beef cattle kept on different types of floor after short- or long-term housing.
Buruli Ulcer
Topical exposure to exogenous ultraviolet-irradiated urocanic acid enhances Mycobacterium ulcerans infection in a Crl:IAF(HA)-hrBR hairless guinea-pig model of Buruli ulcer disease.
Ultraviolet radiation enhances both the nodular and ulcerative forms of Mycobacterium ulcerans infection in a Crl:IAF(HA)-hrBR hairless guinea pig model of Buruli ulcer disease.
Carcinogenesis
A strain of hairless mouse susceptible to tumorigenesis by TPA alone: studies with 8-methoxypsoralen and solar simulated radiation.
A STUDY OF EPIDERMAL TUMOURIGENESIS IN THE HAIRLESS MOUSE WITH SINGLE AND WITH REPEATED APPLICATIONS OF 3-METHYLCHOLANTHRENE AT DIFFERENT DOSAGES.
Activation of telomerase and its association with G1-phase of the cell cycle during UVB-induced skin tumorigenesis in SKH-1 hairless mouse.
Analysis of cell kinetics during ultraviolet light-induced epidermal carcinogenesis in hairless mice.
Biochemical parameters of epidermal aging in the hairless mouse and the relationship to UV-carcinogenesis.
Cancer chemopreventive effects of Pinus Maritima bark extract on ultraviolet radiation and ultraviolet radiation-7,12,dimethylbenz(a)anthracene induced skin carcinogenesis of hairless mice.
Carcinogenesis induced by UVA (365-nm) radiation: the dose-time dependence of tumor formation in hairless mice.
Carcinogenesis studies with benzoyl peroxide (Panoxyl gel 5%).
Cell cycle effects and concomitant p53 expression in hairless murine skin after longwave UVA (365 nm) irradiation: a comparison with UVB irradiation.
Cell metabolism in experimental skin carcinogenesis. 1. Effects of benzene and some polycyclic hydrocarbons on the endogenous dehydrogenase activity in the epidermis and the stripped skin in hairless mice studied by means of a tetrazolium reduction method.
Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
Chemoprotective Effects of Dietary Grape Powder on UVB Radiation-Mediated Skin Carcinogenesis in SKH-1 Hairless Mice.
Chlorpromazine reduces UV-induced squamous cell carcinogenesis in hairless mice and enhances UV-induced DNA damage in cultured cells.
Chronic UVA (365-nm) irradiation induced scratching in hairless mice: dose-time dependency and the effect of ketanserin.
cis-9,trans-11-conjugated linoleic acid down-regulates phorbol ester-induced NF-kappaB activation and subsequent COX-2 expression in hairless mouse skin by targeting IkappaB kinase and PI3K-Akt.
Citral prevents UVB-induced skin carcinogenesis in hairless mice.
Comparison of sensitivity of Swiss albino and hairless Swiss bare mice to two stage skin tumorigenesis.
Comparison of ultraviolet light-induced skin carcinogenesis and ornithine decarboxylase activity in sencar and hairless SKH-1 mice fed a constant level of dietary lipid varying in corn and coconut oil.
Curcumin Protects against UVB-Induced Skin Cancers in SKH-1 Hairless Mouse: Analysis of Early Molecular Markers in Carcinogenesis.
Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-?B signaling pathways in SKH-1 hairless mice skin.
Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis.
Determination of the maximal carcinoma/normal skin ratio after HpD or m-THPC administration in Hairless mice (SKH-1) by fluorescence spectroscopy.
Determination of the maximal tumor/normal skin ratio after HpD or m-THPC administration in hairless mouse (SKh-1) by fluorescence spectroscopy--a non-invasive method.
Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis.
Dietary Feeding of Opuntia Humifusa Inhibits UVB Radiation-Induced Carcinogenesis by Reducing Inflammation and Proliferation in Hairless Mouse Model.
Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice.
Difluoromethylornithine is effective as both a preventive and therapeutic agent against the development of UV carcinogenesis in SKH hairless mice.
Dose-dependent effects of UVB-induced skin carcinogenesis in hairless p53 knockout mice.
Early and late effects of the immunosuppressants rapamycin and mycophenolate mofetil on UV carcinogenesis.
Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells.
Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice.
Effect of dietary lipid on UV light carcinogenesis in the hairless mouse.
Effect of dietary omega-3 and omega-6 fatty acid sources on PUVA-induced cutaneous toxicity and tumorigenesis in the hairless mouse.
Effect of High-Dose Topical Minoxidil on Erythrocyte Quality in SKH1 Hairless Mice.
Effect of immunosuppressive agents and sunscreens on UV carcinogenesis in the hairless mouse.
Effect of ultraviolet (UV) radiation and UVB-absorbing sunscreen ingredients on 7,12-dimethylbenz(a)anthracene-initiated skin tumorigenesis in hairless mice.
Effect on topical 5-methoxypsoralen on tumorigenesis induced in albino and pigmented hairless mouse skin by UV irradiation.
Effects of a High-Fat or High-Sucrose Diet on Ultraviolet B Irradiation-Induced Carcinogenesis and Tumor Growth in Melanin-Possessing Hairless Mice.
Effects of beta-carotene on chemically-induced skin tumors in HRA/Skh hairless mice.
Effects of immunosuppressive therapy on the induction of skin tumors by ultraviolet irradiation in hairless mice.
Effects of mechlorethamine (HN2, nitrogen mustard) on UV-induced carcinogenesis in hairless mouse skin.
Effects of systemic indomethacin on photocarcinogenesis in hairless mice.
Effects of the isoflavone 4',5,7-trihydroxyisoflavone (genistein) on psoralen plus ultraviolet A radiation (PUVA)-induced photodamage.
Emerging research on equol and cancer.
Enhancement of methylnitrosourea skin carcinogenesis by inhibiting cell proliferation with hydroxyurea or skin extracts.
Enhancement of methylnitrosourea-induced skin tumorigenesis and carcinogenesis in hairless mice by pretreatment with a mitosis-inhibiting epidermal pentapeptide.
Enhancement of u.v.-induced skin carcinogenesis in the hairless mouse by inoculation with cell-free extracts of skin tumours.
Exposure to soil contaminated with an environmental PCB/PCDD/PCDF mixture modulates ultraviolet radiation-induced non-melanoma skin carcinogenesis in the Crl:SKH1-hrBR hairless mouse.
Failure of UVR dose reciprocity for skin tumorigenesis in hairless mice treated with 8-methoxypsoralen.
Fluorescent lighting enhances chemically induced papilloma formation and increases susceptibility to tumor challenge in mice.
French maritime pine bark (Pinus maritima Lam.) extract (Flavangenol) prevents chronic UVB radiation-induced skin damage and carcinogenesis in melanin-possessing hairless mice.
Hairless mouse skin in two-stage chemical carcinogenesis.
Honokiol, a phytochemical from the Magnolia plant, inhibits photocarcinogenesis by targeting UVB-induced inflammatory mediators and cell cycle regulators: development of topical formulation.
Hydroxyurea enhances methylnitrosourea skin tumorigenesis when given shortly before, but not after, the carcinogen.
Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice.
Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane.
Influence of dietary lipid upon ultraviolet-light carcinogenesis.
Ingenol Disoxate: A Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers.
Inhibition of methylcholanthrene-induced skin carcinogenesis in hairless mice by dimethyl sulfoxide.
Inhibition of methylcholanthrene-induced skin carcinogenesis in hairless mice by the membrane-labilizing agent DMSO.
Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives.
Inhibition of ultraviolet light-induced oxidative events in the skin and internal organs of hairless mice by isoflavone genistein.
Inhibition of ultraviolet-B epidermal ornithine decarboxylase induction and skin carcinogenesis in hairless mice by topical indomethacin and triamcinolone acetonide.
Inhibition of ultraviolet-induced carcinogenesis by all-trans retinoic acid.
Inhibitory effect of glycolic acid on ultraviolet-induced skin tumorigenesis in SKH-1 hairless mice and its mechanism of action.
INK4a-ARF mutations in skin carcinomas from UV irradiated hairless mice.
Intake of high-fat diet stimulates the risk of ultraviolet radiation-induced skin tumors and malignant progression of papillomas to carcinoma in SKH-1 hairless mice.
Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model.
Kdm1a promotes SCLC progression by transcriptionally silencing the tumor suppressor Rest.
Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling.
Mechanism of selenium-induced inhibition of arsenic-enhanced UVR carcinogenesis in mice.
Micronuclei in mouse skin cells following in vivo exposure to benzo[a]pyrene, 7,12-dimethylbenz[a]anthracene, chrysene, pyrene and urethane.
Moderate enhancement of the promotion phase of skin tumorigenesis in hairless mice by topical pretreatment with a mitosis-inhibiting epidermal pentapeptide.
Modulation of dietary vitamins E and C fails to ameliorate b-carotene exacerbation of UV carcinogenesis in mice.
Modulation of UVB-induced Carcinogenesis by Activation of Alternative DNA Repair Pathways.
Molecular and functional aspects of the hairless (hr) gene in laboratory rodents and humans.
Molecular cloning and functional characterization of a homolog of the transcriptional regulator CSL in Litopenaeus vannamei.
Molecular Mechanisms Underlying Chemopreventive Activities of Glycyrrhizic Acid against UVB-Radiation-Induced Carcinogenesis in SKH-1 Hairless Mouse Epidermis.
Morphometric evaluation of dark and clear epidermal basal cells during early 2-stage chemical skin carcinogenesis in the hairless mouse using two different fixation methods.
Mutations in cancer genes of UV-induced skin tumors of hairless mice.
Mutations in ras oncogenes: rare events in ultraviolet B radiation-induced mouse skin tumorigenesis.
Myricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo.
Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis.
Natural killer cell activity during UVR-induced skin tumor formation in the Skh hairless mouse.
Nitric oxide-releasing sulindac is a novel skin cancer chemopreventive agent for UVB-induced photocarcinogenesis.
Noninvasive Optical Imaging of UV-Induced Squamous Cell Carcinoma in Murine Skin: Studies of Early Tumor Development and Vitamin D Enhancement of Protoporphyrin IX Production.
Nuclear GSK3? promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22.
Olive Leaf Extract and Its Main Component Oleuropein Prevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice.
Oncogenes and growth factors as indicators of carcinogen exposure.
Oncogenic features of PHF8 histone demethylase in esophageal squamous cell carcinoma.
Oral administration of dimethylarsinic acid, a main metabolite of inorganic arsenic, in mice promotes skin tumorigenesis initiated by dimethylbenz(a)anthracene with or without ultraviolet B as a promoter.
Oral Feeding of Pomegranate Fruit Extract Inhibits Early Biomarkers of UVB Radiation-induced Carcinogenesis in SKH-1 Hairless Mouse Epidermis.
Over-expression of lysine-specific demethylase 1 predicts tumor progression and poor prognosis in human esophageal cancer.
Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
p38 MAP kinase plays a functional role in UVB-Induced mouse skin carcinogenesis.
p53 mutations as a marker of skin cancer risk: comparison of UVA and UVB effects.
p53 mutations in cutaneous lesions induced in the hairless mouse by a solar ultraviolet light simulator.
Photochemical genotoxicity and photochemical carcinogenesis--two sides of a coin?
Photoprotective effect of Pothomorphe umbellata on UVB radiation-induced biomarkers involved in carcinogenesis of hairless mouse epidermis.
Photosensitizing effects of 8-methoxypsoralen on the skin of hairless mice--II. Strain and spectral differences for tumorigenesis.
Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model.
PKCvarepsilon Overexpression, Irrespective of Genetic Background, Sensitizes Skin to UVR-Induced Development of Squamous-Cell Carcinomas.
Potentiating effect of dietary vitamin A on photocarcinogenesis in hairless mice.
Protection against ultraviolet B radiation-induced effects in the skin of SKH-1 hairless mice by a polyphenolic fraction isolated from green tea.
Protection against ultraviolet B radiation-induced photocarcinogenesis in hairless mice by green tea polyphenols.
Protective Effect of Inositol Hexaphosphate Against UVB Damage in HaCaT Cells and Skin Carcinogenesis in SKH1 Hairless Mice.
Protective effect of the isoflavonoid equol against hairless mouse skin carcinogenesis induced by UV radiation alone or with a chemical cocarcinogen.
Protective effect of topically applied olive oil against photocarcinogenesis following UVB exposure of mice.
Protective effects of silymarin against photocarcinogenesis in a mouse skin model.
Pyrimidine dimer induction and removal in the epidermis of hairless mice: inefficient repair in the genome overall and rapid repair in the H-ras sequence.
Quercetin prevents UV-induced local immunosuppression, but does not affect UV-induced tumor growth in SKH-1 hairless mice.
Rapid body weight gain increases the risk of UV radiation-induced skin carcinogenesis in SKH-1 hairless mice.
Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N-acetyltransferase.
Retinoic acid and photocarcinogenesis--a controversy.
S/RV Cri-ba, a hairless mouse strain sensitive to skin tumorigenesis by suboptimal doses of 7,12-dimethylbenz[a]anthracene, initiation-promotion and two stage promotion protocols.
Selenium inhibits UV-light-induced skin carcinogenesis in hairless mice.
Sex differences and pathology status correlated to the toxicity of some common carcinogens in experimental skin carcinoma.
Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
SKHIN/Sprd, a new genetically defined inbred hairless mouse strain for UV-induced skin carcinogenesis studies.
Skin tumorigenesis and carcinogenesis studies with 7,12-dimethylbenz[a]anthracene, ultraviolet light, benzoyl peroxide (Panoxyl gel 5%) and ointment gel.
Skin-tumour-promoting activity of processed bidi tobacco in hairless S/RV Cri-ba mice.
Stimulation of ultraviolet-induced carcinogenesis by 1,3-Bis(2-chloroethyl)-1-nitrosourea.
Studies of the carcinogenesis and tumorigenesis of skin applications of dodecylbenzene on hairless mice.
Studying skin tumourigenesis and progression in immunocompetent hairless SKH1-hr mice using chronic 7,12-dimethylbenz(a)anthracene topical applications to develop a useful experimental skin cancer model.
Sun-sensitizing effects of PKCepsilon shine on multiple mouse strains.
Sunless skin tanning with dihydroxyacetone delays broad-spectrum ultraviolet photocarcinogenesis in hairless mice.
Sunscreens prevent ultraviolet photocarcinogenesis.
Supplementing vitamin B6 to a low vitamin B6 diet exaggerates UVB-Induced skin tumorigenesis in DMBA-treated hairless mice.
Suppression of the solar ultraviolet-induced skin carcinogenesis by TOPK inhibitor HI-TOPK-032.
Targeting PRPK and TOPK for skin cancer prevention and therapy.
The carcinogenic risks of modern tanning equipment: is UV-A safer than UV-B?
The early effects of a single application of acetone and various doses of 7,12-dimethylbenz(alpha)anthracene on CD-1 and hairless mouse epidermis. A cell kinetic study of so-called initiation and complete carcinogenesis (initiation plus promotion) in chemical skin tumor induction.
The effect of oral quercetin on UVB-induced tumor growth and local immunosuppression in SKH-1.
The effect of the antihistamine cimetidine on ultraviolet-radiation-induced tumorigenesis in the hairless mouse.
The effects of two UVB radiation-absorbing sunscreens on UV radiation-induced carcinogenesis, suppression of the contact hypersensitivity response and histological changes in the hairless mouse.
The histone demethylase lysine-specific demethylase-1-mediated epigenetic silence of KLF2 contributes to gastric cancer cell proliferation, migration, and invasion.
The inefficacy of riboflavin against ultraviolet-induced carcinogenesis.
The mitigating effect of dietary antioxidants on chemically-induced carcinogenesis.
The refractoriness of the skin of hairless mice to chemical carcinogenesis.
The role of orally administered dimethylarsinic acid, a main metabolite of inorganic arsenics, in the promotion and progression of UVB-induced skin tumorigenesis in hairless mice.
The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice.
The sensitivity of the skin of hairless mice to chemical carcinogenesis.
The skin tumorigenic and carcinogenic effects of different doses, numbers of dose fractions and concentrations of 7,12-dimethylbenz[a]anthracene in acetone applied on hairless mouse epidermis. Possible implications for human carcinogenesis.
Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting.
Topical treatment with black raspberry extract reduces cutaneous UVB-induced carcinogenesis and inflammation.
Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis.
Topical tretinoin enhances corticosteroid-induced inhibition of tumorigenesis in hairless mice previously exposed to solar simulating radiation.
Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity.
Tumorigenesis and carcinogenesis studies of a number of insulation oils and fluids on hairless and SENCAR mice with special reference to skin tumours and malignant lymphomas.
Tumorigenesis by short-wave ultraviolet A: papillomas versus squamous cell carcinomas.
Ultrastructure of ultraviolet radiation-induced hairless mouse skin carcinogenesis, with special reference to the epidermal-dermal junction.
Ultraviolet B-induced tumors in pigmented hairless mice, with an unsuccessful attempt to induce cutaneous melanoma.
Ultraviolet carcinogenesis in the hairless mouse skin. Influence of the sunscreen 2-ethylhexyl-p-methoxycinnamate.
Ultraviolet light carcinogenesis in hairless mice: cell kinetics during induction and progression of squamous cell carcinoma as estimated by the double-labeling method.
Ultraviolet radiation-induced non-melanoma skin cancer in the Crl:SKH1:hr-BR hairless mouse: augmentation of tumor multiplicity by chlorophyllin and protection by indole-3-carbinol.
UV-induced skin cancer in a hairless mouse model.
UVA irradiation increases the incidence of epithelial tumors in UVB-irradiated hairless mice.
UVA-induced tumours in pigmented hairless mice and the carcinogenic risks of tanning with UVA.
XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.
[In vitro methods for phototoxicity and photocarcinogenicity testing of drugs]
Carcinoma
Altered patterns of cutaneous xenobiotic metabolism in UVB-induced squamous cell carcinoma in SKH-1 hairless mice.
Chlorpromazine reduces UV-induced squamous cell carcinogenesis in hairless mice and enhances UV-induced DNA damage in cultured cells.
Controlled localized heating and isotretinoin effects in canine squamous cell carcinoma.
Cutaneous transcriptome analysis in NIH hairless mice.
Cysteine protease and its inhibitor in experimentally produced squamous cell carcinomas in hairless mouse skin.
Decreased retinyl ester concentrations in UV-induced murine squamous cell carcinomas.
Determination of endogenous porphyrins and the maximal HpD tumor/normal skin ratio in SKH-1 hairless mice by light induced fluorescence spectroscopy.
Determination of the maximal carcinoma/normal skin ratio after HpD or m-THPC administration in Hairless mice (SKH-1) by fluorescence spectroscopy.
Dietary immunosuppressants do not enhance UV-induced skin carcinogenesis, and reveal discordance between p53-mutant early clones and carcinomas.
Differential expression of glutathione-s-transferase isozymes in murine and human skin tumors.
Dose-dependent effects of UVB-induced skin carcinogenesis in hairless p53 knockout mice.
Early events in UV carcinogenesis--DNA damage, target cells and mutant p53 foci.
Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity.
Effect of varying dose of UV radiation on mammalian skin: simulation of decreasing stratospheric ozone.
Effects of ultraviolet light on nude mice: cutaneous carcinogenesis and possible leukemogenesis.
Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation.
Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC.
Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model.
Grape seed proanthocyanidines and skin cancer prevention: inhibition of oxidative stress and protection of immune system.
Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch(+/-) Mice.
High MHC class I expression correlates with slow growth in UV-induced skin carcinomas in hairless mice.
Hyperbaric hydrogen therapy: a possible treatment for cancer.
Identification of papillomaviral DNA sequences in hairless mouse tumours induced by ultraviolet irradiation.
Impaired skin barrier function in mice with colon carcinoma induced by azoxymethane and dextran sodium sulfate.
Incidence of squamous cell carcinoma in hairless mice irradiated with ultraviolet light in relation to intake of ascorbic acid (vitamin C) and of D, L-alpha-tocopheryl acetate (vitamin E).
Induction of syngeneic intradermal and orthotopic epidermal carcinomas in hairless Skh-1 mice as a reproducible model for experiments.
INK4a-ARF mutations in skin carcinomas from UV irradiated hairless mice.
Intake of high-fat diet stimulates the risk of ultraviolet radiation-induced skin tumors and malignant progression of papillomas to carcinoma in SKH-1 hairless mice.
Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model.
Looking beyond the skin: Cutaneous and systemic oxidative stress in UVB-induced squamous cell carcinoma in hairless mice.
Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling.
Morphological changes in BFU hairless mice injected by homologous tumours -- Ehrlich's and Brno carcinomas.
Multiple large-surface photodynamic therapy sessions with topical or systemic aminolevulinic acid and blue light in UV-exposed hairless mice.
Naproxen Inhibits UVB-induced Basal Cell and Squamous Cell Carcinoma Development in Ptch1(+/-) /SKH-1 hairless mice.
Oncogenic features of PHF8 histone demethylase in esophageal squamous cell carcinoma.
Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice.
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance.
Photodynamic therapy with topical methyl- and hexylaminolevulinate for prophylaxis and treatment of UV-induced SCC in hairless mice.
Physical variables in experimental photocarcinogenesis and quantitative relationships between stages of tumor development.
Reduced ultraviolet irradiation delays subsequent squamous cell carcinomas in hairless mice.
Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice.
Relative susceptibilities of XPA knockout mice and their heterozygous and wild-type littermates to UVB-induced skin cancer.
Repeated treatments with ingenol mebutate for prophylaxis of UV-induced squamous cell carcinoma in hairless mice.
SKHIN/Sprd, a new genetically defined inbred hairless mouse strain for UV-induced skin carcinogenesis studies.
Skin tumor development after UV irradiation and photodynamic therapy is unaffected by short-term pretreatment with 5-fluorouracil, imiquimod and calcipotriol. An experimental hairless mouse study.
Skin tumor development and keratin expression in different experimental models. Relation to inducing agent and target tissue structure.
Skin-tumour-promoting activity of processed bidi tobacco in hairless S/RV Cri-ba mice.
Squamous cell carcinoma produced by ultraviolet light in hairless mice.
Suppression of squamous cell carcinoma in hairless mice by dietary nutrient variation.
Suppression of ultraviolet light-induced tumor formation by dietary antioxidants.
Targeting PRPK and TOPK for skin cancer prevention and therapy.
The characterization of squamous cell carcinoma induced by ultraviolet irradiation in hairless mice.
The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice.
The sensitivity of the skin of hairless mice to chemical carcinogenesis.
Therapeutic and immune effects of 5-aminolevulinic acid photodynamic therapy on UVB-induced squamous cell carcinomas in hairless mice.
Time and dose dependence of acceptance of UV-induced syngeneic tumor implants in chronically UV-exposed hairless mice.
Topical tacrolimus in combination with simulated solar radiation does not enhance photocarcinogenesis in hairless mice.
Treatment of mouse carcinomas with intratumoral injections of hematoporphyrin derivative and red light.
Ultraviolet light carcinogenesis in hairless mice: cell kinetics during induction and progression of squamous cell carcinoma as estimated by the double-labeling method.
UV-induced immunosuppression in the balance.
UV-induced squamous cell carcinomas in the hairless mouse. Morphological characteristics and transplantation in the syngenic and nude mouse.
Vitamin A and its derivatives in experimental photocarcinogenesis: preventive effects and relevance to humans.
XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.
Carcinoma, Basal Cell
Cutaneous transcriptome analysis in NIH hairless mice.
Carcinoma, Hepatocellular
Cytoplasmic translocation of nuclear LSD1 (KDM1A) in human hepatoma cells is induced by its inhibitors.
KDM1A Promotes Immunosuppression in Hepatocellular Carcinoma by Regulating PD-L1 through Demethylating MEF2D.
Overexpression of lysine specific demethylase 1 predicts worse prognosis in primary hepatocellular carcinoma patients.
Polychlorinated biphenyls (PCBs): mutagenicity and carcinogenicity.
Role of the Hypoxia-Related Gene, JMJD1A, in Hepatocellular Carcinoma: Clinical Impact on Recurrence after Hepatic Resection.
Targeting KDM1A attenuates Wnt/?-catenin signaling pathway to eliminate sorafenib-resistant stem-like cells in hepatocellular carcinoma.
Carcinoma, Large Cell
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance.
Carcinoma, Non-Small-Cell Lung
KDM1A promotes tumor cell invasion by silencing TIMP3 in non-small cell lung cancer cells.
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance.
Carcinoma, Squamous Cell
Altered patterns of cutaneous xenobiotic metabolism in UVB-induced squamous cell carcinoma in SKH-1 hairless mice.
Chlorpromazine reduces UV-induced squamous cell carcinogenesis in hairless mice and enhances UV-induced DNA damage in cultured cells.
Controlled localized heating and isotretinoin effects in canine squamous cell carcinoma.
Cysteine protease and its inhibitor in experimentally produced squamous cell carcinomas in hairless mouse skin.
Decreased retinyl ester concentrations in UV-induced murine squamous cell carcinomas.
Dose-dependent effects of UVB-induced skin carcinogenesis in hairless p53 knockout mice.
Early events in UV carcinogenesis--DNA damage, target cells and mutant p53 foci.
Effect of varying dose of UV radiation on mammalian skin: simulation of decreasing stratospheric ozone.
Effects of ultraviolet light on nude mice: cutaneous carcinogenesis and possible leukemogenesis.
Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation.
Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC.
Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model.
Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch(+/-) Mice.
Hyperbaric hydrogen therapy: a possible treatment for cancer.
Identification of papillomaviral DNA sequences in hairless mouse tumours induced by ultraviolet irradiation.
Incidence of squamous cell carcinoma in hairless mice irradiated with ultraviolet light in relation to intake of ascorbic acid (vitamin C) and of D, L-alpha-tocopheryl acetate (vitamin E).
Induction of syngeneic intradermal and orthotopic epidermal carcinomas in hairless Skh-1 mice as a reproducible model for experiments.
Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model.
Looking beyond the skin: Cutaneous and systemic oxidative stress in UVB-induced squamous cell carcinoma in hairless mice.
Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling.
Multiple large-surface photodynamic therapy sessions with topical or systemic aminolevulinic acid and blue light in UV-exposed hairless mice.
Naproxen Inhibits UVB-induced Basal Cell and Squamous Cell Carcinoma Development in Ptch1(+/-) /SKH-1 hairless mice.
Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice.
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance.
Photodynamic therapy with topical methyl- and hexylaminolevulinate for prophylaxis and treatment of UV-induced SCC in hairless mice.
Physical variables in experimental photocarcinogenesis and quantitative relationships between stages of tumor development.
Reduced ultraviolet irradiation delays subsequent squamous cell carcinomas in hairless mice.
Relative susceptibilities of XPA knockout mice and their heterozygous and wild-type littermates to UVB-induced skin cancer.
Repeated treatments with ingenol mebutate for prophylaxis of UV-induced squamous cell carcinoma in hairless mice.
SKHIN/Sprd, a new genetically defined inbred hairless mouse strain for UV-induced skin carcinogenesis studies.
Skin tumor development after UV irradiation and photodynamic therapy is unaffected by short-term pretreatment with 5-fluorouracil, imiquimod and calcipotriol. An experimental hairless mouse study.
Skin tumor development and keratin expression in different experimental models. Relation to inducing agent and target tissue structure.
Specificity of epidermal chalone extracts for human epidermoid tumour cells in vitro: a preliminary report.
Squamous cell carcinoma produced by ultraviolet light in hairless mice.
Suppression of squamous cell carcinoma in hairless mice by dietary nutrient variation.
Suppression of ultraviolet light-induced tumor formation by dietary antioxidants.
Targeting PRPK and TOPK for skin cancer prevention and therapy.
The characterization of squamous cell carcinoma induced by ultraviolet irradiation in hairless mice.
The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice.
The sensitivity of the skin of hairless mice to chemical carcinogenesis.
Therapeutic and immune effects of 5-aminolevulinic acid photodynamic therapy on UVB-induced squamous cell carcinomas in hairless mice.
Topical tacrolimus in combination with simulated solar radiation does not enhance photocarcinogenesis in hairless mice.
Ultraviolet light carcinogenesis in hairless mice: cell kinetics during induction and progression of squamous cell carcinoma as estimated by the double-labeling method.
UV-induced squamous cell carcinomas in the hairless mouse. Morphological characteristics and transplantation in the syngenic and nude mouse.
Vitamin A and its derivatives in experimental photocarcinogenesis: preventive effects and relevance to humans.
XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.
Cardiomegaly
Inhibition of histone demethylase JMJD1C attenuates cardiac hypertrophy and fibrosis induced by angiotensin II.
The Histone Demethylase JMJD1C Regulates CAMKK2-AMPK Signaling to Participate in Cardiac Hypertrophy.
Cataract
Relationships between acetone, cataracts, and ascorbate in hairless guinea pigs.
Chickenpox
Drug testing for activity against varicella-zoster virus in hairless guinea pigs.
Varicella in hairless guinea pigs.
Chloracne
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCCD) affects keratin 1 and keratin 17 gene expression and differentially induces keratinization in hairless mouse skin.
Alterations in the expression of specific epidermal keratin markers in the hairless mouse by the topical application of the tumor promoters 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Assessment of the chloracnegenic response induced by 3,4,3',4'-tetrachloroazoxybenzene in mice.
Decreased induction of aryl hydrocarbon hydroxylase activity in hyperproliferative hairless mouse epidermis.
Hairless mice as models for chloracne: a study of cutaneous changes induced by topical application of established chloracnegens.
Inflammatory and chloracne-like skin lesions in B6C3F1 mice exposed to 3,3',4,4'-tetrachloroazobenzene for 2 years.
Cholangiocarcinoma
miR-17-92 cluster promotes cholangiocarcinoma growth: evidence for PTEN as downstream target and IL-6/Stat3 as upstream activator.
Choriocarcinoma
Modulating drug resistance by targeting BCRP/ABCG2 using retrovirus-mediated RNA interference.
Cocarcinogenesis
Further evidence against a direct genotoxic mode of action for arsenic-induced cancer.
Colitis
Lactobacillus salivarius LA307 and Lactobacillus rhamnosus LA305 attenuate skin inflammation in mice.
Colonic Neoplasms
MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A.
Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors.
Colorectal Neoplasms
Downregulation of histone demethylase JMJD1C inhibits colorectal cancer metastasis through targeting ATF2.
Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/?-catenin pathway by down-regulating Dickkopf-1 (DKK1).
Significant association between KDM1A promoter hypomethylation and colorectal cancer in Han Chinese.
TSPAN8 promotes colorectal cancer cell growth and migration in LSD1-dependent manner.
Congenital Abnormalities
ADAM "sequence" part II: Hypothesis and speculation.
VITAMIN A-INDUCED CONGENITAL DEFECTS IN HAIRLESS MICE.
Congenital Microtia
[A technique of esthetic rehabilitation of patients with microtia after meatotympanoplasty]
Conjunctivitis
Mousepox outbreak in a laboratory mouse colony.
Contracture
Skin tightening effects of the ultrapulse CO2 laser.
[Pathomorphological observation of the hypertrophic scar induced by injury to conical structure in female red Duroc pig]
Coronary Disease
Novel epigenetic-sensitive clinical challenges both in type 1 and type 2 diabetes.
Cowpox
Cutaneous infections of mice with vaccinia or cowpox viruses and efficacy of cidofovir.
Crush Syndrome
A novel method to assess the severity and prognosis in crush syndrome by assessment of skin damage in hairless rats.
Cysts
'Atrichosis', a new hairless gene with cyst formation in rats.
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCCD) affects keratin 1 and keratin 17 gene expression and differentially induces keratinization in hairless mouse skin.
A definitive role of ornithine decarboxylase in photocarcinogenesis.
Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene.
Atrichia with papular lesions resulting from mutations in the rhesus macaque (Macaca mulatta) hairless gene.
Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis.
Dermal cysts of the rhino mouse develop into unopened sebaceous glands.
Dermal histology of hairless rat derived from Wistar strain.
Evaluation of the hairless rat as a model for in vivo percutaneous absorption.
Experimental leprosy with Mycobacterium lepraemurium in hairless mice (Mus musculus).
Hair loss and cyst formation in hairless and rhino mutant mice.
Histologic changes produced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the skin of mice carrying mutations that affect the integument.
Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors.
Pharmacology of RALGA, a mixture of retinaldehyde and glycolic acid.
Recapitulation of the hairless mouse phenotype using catalytic oligonucleotides: implications for permanent hair removal.
Skin morphology of the mutant hairless USP mouse.
The skin of hairless mice. I. The formation of cysts and the distribution of lipids.
Vitamin A deficiency and the induction of cutaneous toxicity in murine skin by TCDD.
Dehydration
Hydrangea serrata (Thunb.) Ser. Extract Attenuate UVB-Induced Photoaging through MAPK/AP-1 Inactivation in Human Skin Fibroblasts and Hairless Mice.
Mutations of the serine protease CAP1/Prss8 lead to reduced embryonic viability, skin defects, and decreased ENaC activity.
Dermatitis
A novel, topical, nonsteroidal, TRPV1 antagonist, PAC-14028 cream improves skin barrier function and exerts anti-inflammatory action through modulating epidermal differentiation markers and suppressing Th2 cytokines in atopic dermatitis.
Bathing Effects of Various Seawaters on Allergic (Atopic) Dermatitis-Like Skin Lesions Induced by 2,4-Dinitrochlorobenzene in Hairless Mice.
Blockade of atopic dermatitis-like skin lesions by DA-9102, a natural medicine isolated from Actinidia arguta, in the Mg-deficiency induced dermatitis model of hairless rats.
Characteristics of spontaneous erythema appeared in hairless rats.
Co-treatment with retinyl retinoate and a PPAR? agonist reduces retinoid dermatitis.
Deficiency of n-6 polyunsaturated fatty acids is mainly responsible for atopic dermatitis-like pruritic skin inflammation in special diet-fed hairless mice.
Delayed type allergic itch-associated response induced by toluene-2,4-diisocyanate in hairless mice.
Diet-induced dermatitis response of hairless rats to systemic treatment with cyclosporin A (Sandimmun), cyclosporin H and FK506.
Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum.
Impact of the Gly573Ser substitution in TRPV3 on the development of allergic and pruritic dermatitis in mice.
In vivo microdialysis for the investigation of drug levels in the dermis and the effect of barrier perturbation on cutaneous drug penetration. Studies in hairless rats and human subjects.
Inhibitory effect of the leukotriene B4 receptor antagonist against hypomagnesic diet-induced dermatitis in hairless rats.
Nonspecific hypersensitivity of the skin.
Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice.
Role of TRPV3 in immune response to development of dermatitis.
Superoxide anion in polymorphonuclear leukocytes of hairless rats suffering from magnesium-deficiency dermatitis.
Suppression of DNCB-Induced Atopic Skin Lesions in Mice by Wikstroemia indica Extract.
The hypomagnesic rat model: dermatitis-prone hairless rats with mild magnesium depletion fed a diet low in lipids did not develop pruritic dermatitis.
The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active.
[Histological study of magnesium deficiency dermatitis in hairless rats]
[Magnesium deficiency dermatitis--changes in leukotriene levels and effects of azelastine hydrochloride on the dermatitis and leukotriene B4]
Dermatitis, Allergic Contact
Percutaneous absorption and anti-inflammatory effect of a substance P receptor antagonist: spantide II.
Dermatitis, Atopic
A lamellar body mimetic system for the treatment of oxazolone-induced atopic dermatitis in hairless mice.
A new flavonoid from Stellera chamaejasme L., stechamone, alleviated 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in a murine model.
Balneotherapeutic effects of high mineral spring water on the atopic dermatitis-like inflammation in hairless mice via immunomodulation and redox balance.
Chamaejasmine Isolated from Wikstroemia dolichantha Diels Suppresses 2,4-Dinitrofluoro-benzene-Induced Atopic Dermatitis in SKH-1 Hairless Mice.
Deficiency of n-6 polyunsaturated fatty acids is mainly responsible for atopic dermatitis-like pruritic skin inflammation in special diet-fed hairless mice.
Dietary deficiencies of unsaturated fatty acids and starch cause atopic dermatitis-like pruritus in hairless mice.
Effect of loratadine on mouse models of atopic dermatitis associated pruritus.
Effects of ?-carotene on oxazolone-induced atopic dermatitis in hairless mice.
Effects of Bambusae caulis in Liquamen on the development of atopic dermatitis-like skin lesions in hairless mice.
Effects of Post-administration of ?-Carotene on Diet-induced Atopic Dermatitis in Hairless Mice.
Ethanol aggravates itch-related scratching in hairless mice developing atopic dermatitis.
Impact on inflammation and recovery of skin barrier by nordihydroguaiaretic Acid as a protease-activated receptor 2 antagonist.
In vitro skin permeation and anti-atopic efficacy of lipid nanocarriers containing water soluble extracts of Houttuynia cordata.
Influence of Hot Spring Water on Fatty Acid Composition of Skin Surface Lipids in Hairless Mouse Model of Atopic Dermatitis.
Objective evaluation of the efficacy of daily topical applications of cosmetics bases using the hairless mouse model of atopic dermatitis.
Oral Intake of Lactobacillus helveticus NS8 Alleviates Ovalbumin-Induced Atopic Dermatitis in SKH-1 Hairless Mice.
Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice.
Pimecrolimus (Elidel, SDZ ASM 981)--preclinical pharmacologic profile and skin selectivity.
Role of TRPV3 in immune response to development of dermatitis.
Stellera chamaejasme and Its Main Compound Luteolin 7-O-Glucoside Alleviates Skin Lesions in Oxazolone- and 2,4-Dinitrochlorobenzene-Stimulated Murine Models of Atopic Dermatitis.
Synergetic effects of prednisolone and olopatadine on atopic dermatitis model of hairless mice.
Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin.
Topical Pioglitazone Nanoformulation for the Treatment of Atopic Dermatitis: Design, Characterization and Efficacy in Hairless Mouse Model.
Dermatitis, Contact
A new animal model for contact dermatitis: the hairless guinea pig.
An isoflavone extract from soybean cake suppresses 2,4-dinitrochlorobenzene-induced contact dermatitis.
Carnosine (beta-alanylhistidine) protects from the suppression of contact hypersensitivity by ultraviolet B (280-320 nm) radiation or by cis urocanic acid.
Contact dermatitis caused by sunless tanning treatment with dihydroxyacetone in hairless descendants of Mexican hairless dogs.
Contact hypersensitivity to stainless steel cages (chromium metal) in hairless descendants of mexican hairless dogs.
Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5.
Dietary butter protects against ultraviolet radiation-induced suppression of contact hypersensitivity in Skh:HR-1 hairless mice.
Differential photoimmunoprotection by sunscreen ingredients is unrelated to epidermal cis urocanic acid formation in hairless mice.
Effect of sodium lauryl sulfate-induced skin irritation on in vitro percutaneous absorption of four drugs.
Effect of sodium lauryl sulfate-induced skin irritation on in vivo percutaneous penetration of four drugs.
Epidermal Hyperplasia and Elevated HB-EGF are More Prominent in Retinoid Dermatitis Compared with Irritant Contact Dermatitis Induced by Benzalkonium Chloride.
Establishment of an atopic dermatitis-like skin model in a hairless mouse by repeated elicitation of contact hypersensitivity that enables to conduct functional analyses of the stratum corneum with various non-invasive biophysical instruments.
Hazards of urocanic acid as a cosmetic ingredient.
Interdependence between heme oxygenase-1 induction and estrogen-receptor-beta signaling mediates photoimmune protection by UVA radiation in mice.
Lack of correlation between suppression of contact hypersensitivity by UV radiation and photoisomerization of epidermal urocanic acid in the hairless mouse.
Murine auricular transepidermal water loss -- a novel approach for evaluating irritant skin reaction in mice.
Pathological findings in cumulative irritation induced by SLS and croton oil in hairless mice.
Protection Against Photoaging in the Hairless Mouse by the Isoflavone Equol.
Protection against photoaging in the hairless mouse by the isoflavone equol.
Suppressive effect of 2-acetyl-4-tetrahydroxybutylimidazole on contact hypersensitivity in the Skh: HR hairless mouse.
The effects of two UVB radiation-absorbing sunscreens on UV radiation-induced carcinogenesis, suppression of the contact hypersensitivity response and histological changes in the hairless mouse.
Dermatitis, Phototoxic
Acute skin phototoxicity in hairless mice following exposure to crude shale oil or natural petroleum oil.
Cutaneous phototoxicity reactions.
Different biologic effectiveness of blacklight fluorescent lamps available for therapy with psoralens plus ultraviolet A.
Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice.
Phototoxicity to sulphonamide derived oral antidiabetics and diuretics. Comparative in vitro and in vivo investigations.
Phototoxicity to sulphonamide-derived oral antidiabetics and diuretics: investigations in hairless mice.
Protection against photodynamic therapy (PDT)-induced photosensitivity by fabric materials.
Quantitative assessment of phototoxicity in the skin of hairless mice.
Dermoid Cyst
Corneal dermoid in a hairless guinea pig.
Encephalocraniocutaneous Lipomatosis.
[Developmental abnormalities and nevi of the scalp].
Diabetes Mellitus
Characteristics of the epidermis and stratum corneum of hairless mice with experimentally induced diabetes mellitus.
Diabetes Mellitus, Type 1
Characteristics of the epidermis and stratum corneum of hairless mice with experimentally induced diabetes mellitus.
Diabetic Nephropathies
Magnoflorine Ameliorates Inflammation and Fibrosis in Rats With Diabetic Nephropathy by Mediating the Stability of Lysine-Specific Demethylase 3A.
Diphtheria
A novel hairless mouse model on an atopic dermatitis-prone genetic background generated by receptor-mediated transgenesis.
Transcutaneous vaccination using a hydrogel patch induces effective immune responses to tetanus and diphtheria toxoid in hairless rat.
Diverticulum
Scrotal island flap urethroplasty in the management of bulbar urethral strictures.
DNA Repair-Deficiency Disorders
Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity.
Ectodermal Dysplasia
A mutation in hairless dogs implicates FOXI3 in ectodermal development.
Clinical and histological characterization of hair coat and glandular tissue of Chinese crested dogs.
Scalp-Ear-Nipple syndrome: first report of a Potassium channel tetramerization domain-containing 1 in-frame insertion and review of the literature.
The dental phenotype of hairless dogs with FOXI3 haploinsufficiency.
Ectodermal Dysplasia 1, Anhidrotic
Dental anomalies and lesions in Eastern Atlantic harbor seals, Phoca vitulina vitulina (Carnivora, Phocidae), from the German North Sea.
Ectromelia
Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - An animal model of smallpox.
[Demonstration of an ectromelia enzootic in hairless mice]
Endometrial Neoplasms
LSD1 sustains estrogen-driven endometrial carcinoma cell proliferation through the PI3K/AKT pathway via di-demethylating H3K9 of cyclin D1.
Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.
Epidermal Cyst
Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch(+/-) Mice.
Epidermolysis Bullosa, Junctional
Animal models for skin blistering conditions: absence of laminin 5 causes hereditary junctional mechanobullous disease in the Belgian horse.
Erythema
1,2-Bis[(3-Methoxyphenyl)Methyl]Ethane-1,2-Dicarboxylic Acid Reduces UVB-Induced Photodamage In Vitro and In Vivo.
8-hydroxy-2'-deoxyguanosine is increased in epidermal cells of hairless mice after chronic ultraviolet B exposure.
A comparison between a tristimulus colorimeter (Minolta ChromaMeter CR-200) and two spectrophotometers (Minolta Spectrophotometer CM-508i and CM-2002). Quantification of UV-B induced erythema in a hairless guinea pig model.
A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy.
Acute Ultraviolet Radiation Perturbs Epithelialization but not the Biomechanical Strength of Full-thickness Cutaneous Wounds.
Alterations to eye structures in hairless mice by long-term ultraviolet irradiation. A histopathological study.
Biopositive effects of low-dose UVB on epidermis: coordinate upregulation of antimicrobial peptides and permeability barrier reinforcement.
BMS-229724 is a tight-binding inhibitor of cytosolic phospholipase A2 that acts at the lipid/water interface and possesses anti-inflammatory activity in skin inflammation models.
Carcinogenic potential of fluorescent UV tanning sources can be estimated using the CIE erythema action spectrum.
Characteristics of spontaneous erythema appeared in hairless rats.
Chyawanprash, a formulation of traditional Ayurvedic medicine, shows a protective effect on skin photoaging in hairless mice.
Clinical, histologic, and electron microscopy study of skin exposed to low-frequency ultrasound.
Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice.
Collagen metabolism in ultraviolet irradiated hairless mouse skin and its correlation to histochemical observations.
Daily Variation of UV-induced Erythema and the Action of Solar Filters.
Differential photoimmunoprotection by sunscreen ingredients is unrelated to epidermal cis urocanic acid formation in hairless mice.
Effect of methyl substitution of benzene on the percutaneous absorption and skin irritation in hairless rats.
Effects of Bambusae caulis in Liquamen on the development of atopic dermatitis-like skin lesions in hairless mice.
Effects of Egg Shell Membrane Hydrolysates on UVB-radiation-induced Wrinkle Formation in SKH-1 Hairless Mice.
Effects of the aminophenol analogue p-Dodecylaminophenol on mouse skin.
Estradiol protects dermal hyaluronan/versican matrix during photoaging by release of epidermal growth factor from keratinocytes.
Evaluation of a topical iron chelator in animals and in human beings: short-term photoprotection by 2-furildioxime.
Evaluation of EpiDerm full thickness-300 (EFT-300) as an in vitro model for skin irritation: Studies on aliphatic hydrocarbons.
Exopolysaccharides Isolated from Milk Fermented with Lactic Acid Bacteria Prevent Ultraviolet-Induced Skin Damage in Hairless Mice.
Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice.
High death rate in mice treated topically with diclofenac.
In Vitro and In Vivo Studies on Protective Action of N-Phenethyl Caffeamide against Photodamage of Skin.
In vitro antioxidant and in vivo photoprotective effects of an association of bioflavonoids with liposoluble vitamins.
Influence of fish oil supplementation on the minimal erythema dose in humans.
Influence of the formulation on the in vitro transdermal penetration of sodium diclofenac. Evaluation of the topical and systemic anti-inflammatory activity in the rat.
Inhibitory Effects of Dietary Spirulina platensis on UVB-Induced Skin Inflammatory Responses and Carcinogenesis.
Involvement of changes in stratum corneum keratin in wrinkle formation by chronic ultraviolet irradiation in hairless mice.
Naringenin targets ERK2 and suppresses UVB-induced photoaging.
Noninvasive Assessment of UV-induced Skin Damage: Comparison of Optical Measurements to Histology and MMP Expression.
Percutaneous absorption and skin irritation upon low-level prolonged dermal exposure to nonane, dodecane and tetradecane in hairless rats.
Photoprotective effect of black tea extracts against UVB-induced phototoxicity in skin.
Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice.
Production of ultraviolet-light-induced skin erythema in the hairless rat: a comparison with the haired rat in screening for anti-inflammatory drugs.
Protective Effect of Dermal Brimonidine Applications Against UV Radiation-induced Skin Tumors, Epidermal Hyperplasia and Cell Proliferation in the Skin of Hairless Mice.
Psoralen-containing sunscreen induces phototoxicity and epidermal ornithine decarboxylase activity.
Radioactive treatment of a murine melanoma using a (32)P-patch.
Reduction of erythema in hairless guinea pigs after cutaneous sulfur mustard vapor exposure by pretreatment with niacinamide, promethazine and indomethacin.
Scar formation following excisional and burn injuries in a red Duroc pig model.
Skin Hydration Effects of Scale-Up Fermented Cyclopia intermedia against Ultraviolet B-Induced Damage in Keratinocyte Cells and Hairless Mice.
Skin tumor development after UV irradiation and photodynamic therapy is unaffected by short-term pretreatment with 5-fluorouracil, imiquimod and calcipotriol. An experimental hairless mouse study.
Suppression of DNCB-Induced Atopic Skin Lesions in Mice by Wikstroemia indica Extract.
Systemic protection by antioxidants against UVL-induced erythema.
The epidermal cell kinetic response to ultraviolet B irradiation combines regenerative proliferation and carcinogen associated cell cycle delay.
The induction of erythema, edema, and the polyamine synthesis enzymes ornithine decarboxylase and S-adenosyl-L-methionine decarboxylase in hairless mouse skin by psoralens and longwave ultraviolet light.
The mouse intradermal test, a well-established and reliable model in skin tolerance testing.
Therapeutic Effects of Cold-Pressed Perilla Oil Mainly Consisting of Linolenic acid, Oleic Acid and Linoleic Acid on UV-Induced Photoaging in NHDF Cells and SKH-1 Hairless Mice.
Topical all-trans retinoic acid stimulates collagen synthesis in vivo.
Topical application of artesunate on guinea pig allergic contact dermatitis.
Topical tocopherol acetate reduces post-UVB, sunburn-associated erythema, edema, and skin sensitivity in hairless mice.
Topical tretinoin enhances corticosteroid-induced inhibition of tumorigenesis in hairless mice previously exposed to solar simulating radiation.
Topical tretinoin increases the tropoelastin and fibronectin content of photoaged hairless mouse skin.
Ultraviolet B irradiation induces epidermal regeneration with rapidly cycling cells.
[Mechanism of Inhibitory Effects of Cherry Bark-containing Jumihaidokuto on Benzoyl Peroxide Induced Erythema in Hairless Mice].
Esophageal Neoplasms
Histone demethylase JMJD1C regulates esophageal cancer proliferation Via YAP1 signaling.
LPE-1, an orally active pyrimidine derivative, inhibits growth and mobility of human esophageal cancers by targeting LSD1.
Lysine-specific demethylase-1 contributes to malignant behavior by regulation of invasive activity and metabolic shift in esophageal cancer.
Esophageal Squamous Cell Carcinoma
Oncogenic features of PHF8 histone demethylase in esophageal squamous cell carcinoma.
Exanthema
Atopic dermatitis-like symptoms in hypomagnesaemic hairless rats are prevented and inhibited by systemic or topical SDZ ASM 981.
Atrichia with papular lesions resulting from a nonsense mutation within the human hairless gene.
Epidermal tissue as a primary site of replication of lymphocytic choriomeningitis virus in small experimental hosts.
Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - An animal model of smallpox.
Varicella in hairless guinea pigs.
Familial Hypophosphatemic Rickets
Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene.
Interactions of the vitamin D receptor with the corepressor hairless: analysis of hairless mutants in atrichia with papular lesions.
Fibroma
Orf virus infection in Alaskan mountain goats, Dall's sheep, muskoxen, caribou and Sitka black-tailed deer.
Focal Dermal Hypoplasia
Encephalocraniocutaneous lipomatosis accompanied by the formation of bone cysts: Harboring clues to pathogenesis?
Folliculitis
Dermatitis from purified sea algae toxin (debromoaplysiatoxin).
Foot-and-Mouth Disease
[Foot-and-mouth disease and its differential diagnoses].
Gastritis
A euthymic hairless mouse model of Helicobacter pylori colonization and adherence to gastric epithelial cells in vivo.
MicroRNA-329 inhibits cell proliferation and tumor growth while facilitates apoptosis via negative regulation of KDM1A in gastric cancer.
Gaucher Disease
Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease.
Genetic Diseases, Inborn
Conformational Dynamics Underlies Different Functions of Human KDM7 Histone Demethylases.
Ligand-independent regulation of the hairless promoter by vitamin D receptor.
LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors.
Glioblastoma
Hairless regulates p53 target genes to exert tumor suppressive functions in glioblastoma.
Nuclear GSK3? promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22.
Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma.
Glioma
Development of an intracerebral glioma model in whole body irradiated hairless rats.
Intracerebral C6 glioma model in female hairless rats: assessment by using MRI and follow-up of irradiation.
Long non-coding RNA HOTAIR promotes glioblastoma cell cycle progression in an EZH2 dependent manner.
Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway.
Glomerulonephritis, Membranoproliferative
A new mutant hairless mouse with lymph node hyperplasia and late onset of autoimmune pathology.
glucosylceramidase deficiency
Consequences of beta-glucocerebrosidase deficiency in epidermis. Ultrastructure and permeability barrier alterations in Gaucher disease.
Goiter
Histopathologic features of the skin of hairless newborn pigs with goiter.
Granuloma
Folliculitis Decalvans and Lichen Planopilaris Phenotypic Spectrum-A Series of 7 New Cases With Focus on Histopathology.
Hamartoma
Hairless Hyperhidrotic Plaque in a Young Male.
The effect of sebocytes cultured from nevus sebaceus on hair growth.
Hemangioma
[Developmental abnormalities and nevi of the scalp].
Hematologic Neoplasms
Histone demethylase LSD1 controls the phenotypic plasticity of cancer cells.
Hematuria
Poikilodermia, anhidrosis, hairless body, neurogenic muscle atrophy, and recurrent hematuria: a new syndrome?
Herpes Labialis
Effect of immunization with herpes simplex virus type-1 (HSV-1) glycoprotein D (gD) plus the immune enhancer GPI-0100 on infection with HSV-1 or HSV-2.
Herpes Simplex
Chemotherapeutic efficacy of E-5-(2-bromovinyl)-2'deoxyuridine for orofacial infection with herpes simplex virus type 1 in mice.
Combined antiviral effects of acyclovir or bromovinyldeoxyuridine and human immunoglobulin in herpes simplex virus-infected mice.
Correlation of in vivo topical efficacies with in vitro predictions using acyclovir formulations in the treatment of cutaneous HSV-1 infections in hairless mice: an evaluation of the predictive value of the C* concept.
Cutaneously applied acyclovir acts systemically in the treatment of herpetic infection in the hairless mouse.
Differential effects of E-5-(2-bromovinyl)-2'-deoxyuridine on infections with herpes simplex virus type 1 and type 2 in hairless mice.
Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on the acute local phase of herpes simplex virus-induced skin infections in mice and the establishment of latency.
Effect of immune serum on the establishment of herpes simplex virus infection in trigeminal ganglia of hairless mice.
Effect of polyanionic compounds on intracutaneous and intravaginal herpesvirus infection in mice: impact on the search for vaginal microbicides with anti-HIV activity.
Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice.
Efficacy of 2'-nor-2'-deoxyguanosine treatment for orofacial herpes simplex virus type 1 skin infections in mice.
Efficacy of 5,6-dihydro-5-azathymidine against cutaneous herpes simplex virus in hairless mice.
Efficacy of a virion envelope herpes simplex virus vaccine against experimental skin infections in hairless mice.
Established latent herpes simplex virus infections of mice not affected by adenosine monophosphate treatment.
Estimation of skin target site acyclovir concentrations following controlled (trans)dermal drug delivery in topical and systemic treatment of cutaneous HSV-1 infections in hairless mice.
Experimental skin infection with an acyclovir resistant herpes simplex virus mutant: response to antiviral treatment and protection against reinfection.
Experimental zoster-like herpes simplex in hairless mice.
Herpes simplex virus skin infection in hairless mice: treatment with antiviral compounds.
Immune response and latent infection after topical treatment of herpes simplex virus infection in hairless mice.
Immune responses in mice against herpes simplex virus: mechanisms of protection against facial and ganglionic infections.
In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine.
Influence of 1-dodecylazacycloheptan-2-one (Azone) on the topical therapy of cutaneous herpes simplex virus type 1 infection in hairless mice with 2',3'-di-O-acetyl-9-beta-D-arabinofuranosyladenine and 5'-O-valeryl-9-beta-D-arabinofuranosyladenine.
Influence of the treatment protocol upon the in vivo efficacy of cidofovir (HPMPC) and of acyclovir (ACV) formulations in topical treatment of cutaneous HSV-1 infection in hairless mice.
Iontophoretic application of adenine arabinoside monophosphate for the treatment of herpes simplex virus type 2 skin infections in hairless mice.
Iontophoretic application of adenine arabinoside monophosphate to herpes simplex virus type 1-infected hairless mouse skin.
Latent herpes simplex virus in ganglia of mice after primary infection and reinoculation at a distant site.
Latent herpes simplex virus infections in sensory ganglia of hairless mice prevented by acycloguanosine.
Latent herpes simplex virus reactivation in the guinea pig. An animal model for recurrent disease.
Latent infections of sensory ganglia as influenced by phosphonoformate treatment of herpes simplex virus-induced skin infections in hairless mice.
Mycophenolate mofetil strongly potentiates the anti-herpesvirus activity of acyclovir.
Novel animal model for evaluating topical efficacy of antiviral agents: flux versus efficacy correlations in the acyclovir treatment of cutaneous herpes simplex virus type 1 (HSV-1) infections in hairless mice.
Orofacial herpes simplex virus infection in hairless mice: latent virus in trigeminal ganglia after topical antiviral treatment.
Phosphonoacetic acid-resistant herpes simplex virus infection in hairless mice.
Protection against establishment of latent infections in mice immunized with a non-pathogenic herpes simplex virus mutant and reinfected with the pathogenic parental strain.
Protective immunity against lethal HSV-1 challenge in mice by nucleic acid-based immunisation with herpes simplex virus type-1 genes specifying glycoproteins gB and gD.
Recurrent cutaneous herpes simplex in hairless mice.
Relationship of skin target site free drug concentration (C*) to the in vivo efficacy: an extensive evaluation of the predictive value of the C* concept using acyclovir as a model drug.
Synergistic therapy by acyclovir and A1110U for mice orofacially infected with herpes simplex viruses.
Thymine arabinoside (Ara-T) topical and iontophoretic application for herpes simplex virus type 1 and type 2 skin infections in hairless mice.
Topical treatment of cutaneous herpes simplex virus infection in hairless mice with (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
Ultraviolet light induces reactivation in a murine model of cutaneous herpes simplex virus-1 infection.
[Experimental herpes simplex virus infection of the skin of hairless mice]
[Penetration and action of edoxudine in vitro and in vivo]
Herpesviridae Infections
Chemotherapy of cutaneous herpesvirus infection of hairless mice.
Hyperemia
Magnesium deficiency allergy-like crisis in hairless rats: a suggested model for inflammation studies.
Hyperpigmentation
Arsenic-mediated hyperpigmentation in skin via NF-kappa B/endothelin-1 signaling in an originally developed hairless mouse model.
Depigmentation and rejuvenation effects of kinetin on the aged skin of hairless descendants of Mexican hairless dogs.
Efficacy of hydroquinone in the treatment of cutaneous hyperpigmentation in hairless descendants of Mexican hairless dogs (Xoloitzcuintli).
Generalized cutaneous hyperpigmentation in hairless mice induced by topical dimethylbenzanthracene.
The Standardized Extract of Juniperus communis Alleviates Hyperpigmentation in Vivo HRM-2 Hairless Mice and in Vitro Murine B16 Melanoma Cells.
Whorled hairless nevus of the scalp, linear hyperpigmentation, and telangiectatic nevi of the lower limbs: a novel variant of the "phacomatosis complex".
Hypersensitivity
Characteristics of scratching behavior induced by some chemical mediators in hairless mice.
Comparative studies on the detection of antibodies and delayed hypersensitivity responses with 10 Blastomyces dermatitidis lysate antigens.
Comparative studies on the detection of delayed dermal hypersensitivity in experimental animals with lysate and filtrate antigens of Blastomyces dermatitidis.
Detection of antibodies and delayed hypersensitivity with Rotofor preparative IEF fractions of Blastomyces dermatitidis yeast phase lysate antigen.
Lactobacillus salivarius LA307 and Lactobacillus rhamnosus LA305 attenuate skin inflammation in mice.
Lymphocyte blastogenesis in hairless dogs following stimulation by various mitogens.
Modulation of delayed-type hypersensitivity responses in hairless guinea pigs by peptides derived from enkephalin.
Nonspecific hypersensitivity of the skin.
The use of hairless (IAF/HA-HO) guinea pigs for the determination of delayed-type hypersensitivity to tuberculin.
Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.
Topical acidic cream prevents the development of atopic dermatitis- and asthma-like lesions in murine model.
Topical urocanic acid enhances UV-induced tumour yield and malignancy in the hairless mouse.
Hypersensitivity, Delayed
Immunological phenomena in harmless mice during experimental carcinogenesis induced with long-term topical application of 7, 12-dimethylbenzanthracene (DMBA).
Hypertrichosis
1599: first iconographic description of hepatoerythropoietic porphyria.
[Developmental abnormalities and nevi of the scalp].
Hypohidrosis
Poikilodermia, anhidrosis, hairless body, neurogenic muscle atrophy, and recurrent hematuria: a new syndrome?
Syringolymphoid hyperplasia with alopecia.
Hypopigmentation
Successful treatment of a novel generalized variant of canine discoid lupus erythematosus with oral hydroxychloroquine.
Hypothyroidism
Differential effects of triiodothyronine and the thyroid hormone receptor beta-specific agonist GC-1 on thyroid hormone target genes in the b ain.
Thyroid Hormone Metabolism Defects in a Mouse Model of SBP2 Deficiency.
Hypotrichosis
A distinct gene close to the hairless locus on chromosome 8p underlies hereditary Marie Unna type hypotrichosis in a German family.
A newly identified missense mutation of the HR gene is associated with a novel, unusual phenotype of Marie Unna Hereditary Hypotrichosis 1 including limb deformities.
Characterization of mouse Frizzled-3 expression in hair follicle development and identification of the human homolog in keratinocytes.
Clinical and histological characterization of hair coat and glandular tissue of Chinese crested dogs.
Corrigendum: Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis.
Linkage of Marie-Unna hypotrichosis locus to chromosome 8p21 and exclusion of 10 genes including the hairless gene by mutation analysis.
Locus of dominant hairless gene (Ht) causing abnormal hair and keratinization maps to rat chromosome 10.
Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis.
Marie Unna hereditary hypotrichosis caused by a novel mutation in the human hairless transcript.
Marie Unna hereditary hypotrichosis gene maps to human chromosome 8p21 near hairless.
The Charles River "hairless" rat mutation maps to chromosome 1: allelic with fuzzy and a likely orthologue of mouse frizzy.
The hairless (hr) gene is involved in the congenital hypotrichosis of Valle del Belice sheep.
Total hypotrichosis: genetic form of alopecia not linked to hairless gene.
Ichthyosis
Diazacholesterol-induced ichthyosis in the hairless mouse. Assay for comparative potency of topical retinoids.
Diazacholesterol-induced ichthyosis in the hairless mouse. I. Morphologic, histochemical, and lipid biochemical characterization of a new animal model.
Lipids in the pathogenesis of ichthyosis: topical cholesterol sulfate-induced scaling in hairless mice.
Stratum corneum lipids in disorders of cornification. Steroid sulfatase and cholesterol sulfate in normal desquamation and the pathogenesis of recessive X-linked ichthyosis.
Incontinentia Pigmenti
Anhidrotic and achromians lesions in incontinentia pigmenti.
Infections
Acid-dependent adherence of Helicobacter pylori urease to diverse polysaccharides.
Acyclovir therapy for the orofacial and ganglionic HSV infection in hairless mice.
Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines.
Arbuscular mycorrhizal colonisation outcompetes root hairs in maize under low phosphorus availability.
Chemotherapeutic efficacy of E-5-(2-bromovinyl)-2'deoxyuridine for orofacial infection with herpes simplex virus type 1 in mice.
Come to the Light Side: In Vivo Monitoring of Pseudomonas aeruginosa Biofilm Infections in Chronic Wounds in a Diabetic Hairless Murine Model.
Correlation of in vivo topical efficacies with in vitro predictions using acyclovir formulations in the treatment of cutaneous HSV-1 infections in hairless mice: an evaluation of the predictive value of the C* concept.
Cutaneous infections of mice with vaccinia or cowpox viruses and efficacy of cidofovir.
Cutaneously applied acyclovir acts systemically in the treatment of herpetic infection in the hairless mouse.
Didemnins A and B. Effectiveness against cutaneous herpes simplex virus in mice.
Differential effects of E-5-(2-bromovinyl)-2'-deoxyuridine on infections with herpes simplex virus type 1 and type 2 in hairless mice.
Drug testing for activity against varicella-zoster virus in hairless guinea pigs.
Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on the acute local phase of herpes simplex virus-induced skin infections in mice and the establishment of latency.
Effect of Azone upon the in vivo antiviral efficacy of cidofovir or acyclovir topical formulations in treatment/prevention of cutaneous HSV-1 infections and its correlation with skin target site free drug concentration in hairless mice.
Effect of combined acyclovir and vidarabine on infection with herpes simplex virus in vitro and in vivo.
Effect of immune serum on the establishment of herpes simplex virus infection in trigeminal ganglia of hairless mice.
Effect of polyanionic compounds on intracutaneous and intravaginal herpesvirus infection in mice: impact on the search for vaginal microbicides with anti-HIV activity.
Efficacy of 2'-nor-2'-deoxyguanosine treatment for orofacial herpes simplex virus type 1 skin infections in mice.
Efficacy of a virion envelope herpes simplex virus vaccine against experimental skin infections in hairless mice.
Efficacy of phosphonylmethoxyalkyl derivatives of adenine in experimental herpes simplex virus and vaccinia virus infections in vivo.
Epidermal tissue as a primary site of replication of lymphocytic choriomeningitis virus in small experimental hosts.
Estimation of skin target site acyclovir concentrations following controlled (trans)dermal drug delivery in topical and systemic treatment of cutaneous HSV-1 infections in hairless mice.
Evaluation of 6-azauridine and 5-iododeoxyuridine in the treatment of experimental viral infections.
Evaluation of antioxidant healing formulations in topical therapy of experimental cutaneous and genital herpes simplex virus infections.
Evaluation of imiquimod for topical treatment of vaccinia virus cutaneous infections in immunosuppressed hairless mice.
Experimental cutaneous Bacillus anthracis infections in hairless HRS/J mice.
Experimental skin infection with an acyclovir resistant herpes simplex virus mutant: response to antiviral treatment and protection against reinfection.
Experimental Trichophyton Mentagrophytes infection in hairless and haired dogs.
Far-UVC light prevents MRSA infection of superficial wounds in vivo.
Hairless mice as an experimental model of infection with Leishmania (Leishmania) amazonensis.
Herpes simplex virus skin infection in hairless mice: treatment with antiviral compounds.
How we do it: A novel approach to the skin--abutment interface of the bone-anchored hearing aid: use of local skin flaps.
Immune responses in mice against herpes simplex virus: mechanisms of protection against facial and ganglionic infections.
Inflammatory reactions to staphylococcal protein A in mice.
Influence of 1-dodecylazacycloheptan-2-one (Azone) on the topical therapy of cutaneous herpes simplex virus type 1 infection in hairless mice with 2',3'-di-O-acetyl-9-beta-D-arabinofuranosyladenine and 5'-O-valeryl-9-beta-D-arabinofuranosyladenine.
Influence of the treatment protocol upon the in vivo efficacy of cidofovir (HPMPC) and of acyclovir (ACV) formulations in topical treatment of cutaneous HSV-1 infection in hairless mice.
Investigation of the pathogenesis of varicella-zoster virus infection in guinea pigs by using polymerase chain reaction.
Iontophoretic application of adenine arabinoside monophosphate for the treatment of herpes simplex virus type 2 skin infections in hairless mice.
Latent herpes simplex virus in ganglia of mice after primary infection and reinoculation at a distant site.
Latent infections of sensory ganglia as influenced by phosphonoformate treatment of herpes simplex virus-induced skin infections in hairless mice.
Melanoidin, a food protein-derived advanced maillard reaction product, suppresses Helicobacter pylori in vitro and in vivo.
New antimicrobial peptide kills drug-resistant pathogens without detectable resistance.
Non-dermatophyte Dermatoses Mimicking Dermatophytoses in Humans.
Novel animal model for evaluating topical efficacy of antiviral agents: flux versus efficacy correlations in the acyclovir treatment of cutaneous herpes simplex virus type 1 (HSV-1) infections in hairless mice.
Orf virus infection in Alaskan mountain goats, Dall's sheep, muskoxen, caribou and Sitka black-tailed deer.
Protective immunity against lethal HSV-1 challenge in mice by nucleic acid-based immunisation with herpes simplex virus type-1 genes specifying glycoproteins gB and gD.
Relationship of skin target site free drug concentration (C*) to the in vivo efficacy: an extensive evaluation of the predictive value of the C* concept using acyclovir as a model drug.
Superficial exudates of neutrophils prevent invasion of Bacillus anthracis bacilli into abraded skin of resistant mice.
Susceptibility of HRS/J mice to listeriosis: dynamics of infection.
The antiviral effectiveness of butylated hydroxytoluene on herpes cutaneous infections in hairless mice.
The use of buccal mucosa patch graft in the management of anterior urethral strictures.
Thymine arabinoside (Ara-T) topical and iontophoretic application for herpes simplex virus type 1 and type 2 skin infections in hairless mice.
Topical exposure to exogenous ultraviolet-irradiated urocanic acid enhances Mycobacterium ulcerans infection in a Crl:IAF(HA)-hrBR hairless guinea-pig model of Buruli ulcer disease.
Topical treatment of cutaneous herpes simplex virus infection in hairless mice with (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
Topical treatment of cutaneous vaccinia virus infections in immunosuppressed hairless mice with selected antiviral substances.
Ultraviolet radiation enhances both the nodular and ulcerative forms of Mycobacterium ulcerans infection in a Crl:IAF(HA)-hrBR hairless guinea pig model of Buruli ulcer disease.
Varicella in hairless guinea pigs.
[Dermatophyte infections of the hairless skin and folds. Diagnosis and treatment]
[Infections with dermatophytes of the hairless skin and folds. Diagnosis and treatment]
Infertility
A C. elegans LSD1 demethylase contributes to germline immortality by reprogramming epigenetic memory.
Genetic complexity underlying hybrid male sterility in Drosophila.
Hairless or fertile? Finasteride leads to epididymal changes and infertility in rats.
Infertility, Female
[Morphofunctional characteristics of the reproductive system in female mice of the mutant strain B10-hr rhY]
Influenza, Human
Evaluation of 6-azauridine and 5-iododeoxyuridine in the treatment of experimental viral infections.
Insulin Resistance
Gender-related effects on substrate utilization and metabolic adaptation in hairless spontaneously hypertensive rat.
Intellectual Disability
Encephalocraniocutaneous lipomatosis accompanied by the formation of bone cysts: Harboring clues to pathogenesis?
Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway.
Keloid
Treatment of keloid and hypertrophic scars by iontophoretic transdermal delivery of tranilast.
Keratitis
Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines.
Keratoacanthoma
From actinic keratosis to squamous cell carcinoma.
Keratoconjunctivitis
Case report of listerial keratoconjunctivitis in hairless guinea pigs.
Keratosis
Kinetics and localisation of PpIX fluorescence after topical and systemic ALA application, observed in skin and skin tumours of UVB-treated mice.
Keratosis, Actinic
Multiple large-surface photodynamic therapy sessions with topical or systemic aminolevulinic acid and blue light in UV-exposed hairless mice.
Topical AC-11 abates actinic keratoses and early squamous cell cancers in hairless mice exposed to Ultraviolet A (UVA) radiation.
UV-induced immunosuppression in the balance.
Kidney Neoplasms
Histone Demethylase LSD1 Regulates Kidney Cancer Progression by Modulating Androgen Receptor Activity.
Latent Infection
Experimental skin infection with an acyclovir resistant herpes simplex virus mutant: response to antiviral treatment and protection against reinfection.
Immune response and latent infection after topical treatment of herpes simplex virus infection in hairless mice.
Latent herpes simplex virus in ganglia of mice after primary infection and reinoculation at a distant site.
Latent infections of sensory ganglia as influenced by phosphonoformate treatment of herpes simplex virus-induced skin infections in hairless mice.
Leishmaniasis, Cutaneous
Experimental cutaneous leishmaniasis with Leishmania tropica in albino hairless mice, Mus musculus.
Hairless mice as an experimental model of infection with Leishmania (Leishmania) amazonensis.
Leprosy
Experimental leprosy with Mycobacterium lepraemurium in hairless mice (Mus musculus).
Hairless mice, human leprosy and thymus-derived-lymphocytes.
Leprosy, Lepromatous
Experimental leprosy with Mycobacterium lepraemurium in hairless mice (Mus musculus).
Leukemia
A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells.
Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1.
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.
Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models.
Effect of allelic substitutions at the hairless locus on endogenous ecotropic murine leukemia virus titers and leukemogenesis.
Immunodeficiency and reticulum cell sarcoma in mice segregating for HRS/J and SJL/J genes.
Jmjd1c is dispensable for healthy adult hematopoiesis and Jak2V617F-driven myeloproliferative disease initiation in mice.
Molecular basis for the rhino (hrrh-8J) phenotype: a nonsense mutation in the mouse hairless gene.
Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia.
ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia.
Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes.
Selective DOT1L, LSD1, and HDAC Class I Inhibitors Reduce HOXA9 Expression in MLL-AF9 Rearranged Leukemia Cells, But Dysregulate the Expression of Many Histone-Modifying Enzymes.
Structure and expression of the hairless gene of mice.
Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids.
Targeting the GFI1/1B-CoREST Complex in Acute Myeloid Leukemia.
The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells.
The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation.
[Expression of histone demethylase lysine specific demethylase 1 in acute leukemia and its clinical significance].
Leukemia, Myeloid
Effects of ultraviolet light on nude mice: cutaneous carcinogenesis and possible leukemogenesis.
Leukemia, Myeloid, Acute
CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML.
Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1.
Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models.
LSD1 inhibitors disrupt the GFI1 transcription repressor complex.
Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes.
Lysine-Specific Demethylase 1A as a Promising Target in Acute Myeloid Leukemia.
Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia.
Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes.
Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1.
The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines.
Lichen Planus
Piccardi-Lassueur-Graham-Little syndrome associated with frontal fibrosing alopecia.
[Drug treatment of alopecia].
Lichen Sclerosus et Atrophicus
Anogenital lichen sclerosus: Change of tissue position as pathogenetic factor.
Lipoma
Encephalocraniocutaneous lipomatosis accompanied by the formation of bone cysts: Harboring clues to pathogenesis?
Mosaic Activating Mutations in FGFR1 Cause Encephalocraniocutaneous Lipomatosis.
Lipomatosis
Encephalocraniocutaneous lipomatosis accompanied by the formation of bone cysts: Harboring clues to pathogenesis?
Encephalocraniocutaneous Lipomatosis Without Ocular Malformations.
Encephalocraniocutaneous lipomatosis: a case with unilateral odontomas and review of the literature.
Nevus psiloliparus: a distinct fatty tissue nevus.
Listeriosis
Susceptibility of HRS/J mice to listeriosis: macrophage activity.
Liver Neoplasms
[Function of histone demethylasehistone lysine-specific demethylase 1A in tumor initiation and progression].
Loose Anagen Hair Syndrome
Noonan-like syndrome with loose anagen hair: a new syndrome?
Lung Neoplasms
KDM1A promotes tumor cell invasion by silencing TIMP3 in non-small cell lung cancer cells.
LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.
Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
ORY-1001 Suppresses Cell Growth and Induces Apoptosis in Lung Cancer Through Triggering HK2 Mediated Warburg Effect.
Over-expression of LSD1 promotes proliferation, migration and invasion in non-small cell lung cancer.
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance.
[Function of histone demethylasehistone lysine-specific demethylase 1A in tumor initiation and progression].
Lymphadenopathy
FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation.
Paracortical hyperplasia of superficial lymph nodes in a new mutant strain of hairless rats (ISh): a lesion similar to human dermatopathic lymphadenopathy.
Lymphatic Metastasis
KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer.
Knockdown of KDM1A suppresses tumour migration and invasion by epigenetically regulating the TIMP1/MMP9 pathway in papillary thyroid cancer.
[Comparative proteomics of the serum in patients with nasopharyngeal carcinoma: a study with two-dimensional electrophoresis and MALDI-TOF-MS]
Lymphedema
Inflammatory Manifestations of Experimental Lymphatic Insufficiency.
Lymphoma
miR-101 regulates cell proliferation and apoptosis by targeting KDM1A in diffuse large B cell lymphoma.
Role of ultraviolet radiation in the induction of melanocytic tumors in hairless mice following 7,12-dimethylbenz(a)anthracene application and ultraviolet irradiation.
Tumorigenesis and carcinogenesis studies of a number of insulation oils and fluids on hairless and SENCAR mice with special reference to skin tumours and malignant lymphomas.
Lymphoma, B-Cell
miR-101 regulates cell proliferation and apoptosis by targeting KDM1A in diffuse large B cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
miR-101 regulates cell proliferation and apoptosis by targeting KDM1A in diffuse large B cell lymphoma.
Magnesium Deficiency
Atopic dermatitis-like symptoms in hypomagnesaemic hairless rats are prevented and inhibited by systemic or topical SDZ ASM 981.
Blockade of atopic dermatitis-like skin lesions by DA-9102, a natural medicine isolated from Actinidia arguta, in the Mg-deficiency induced dermatitis model of hairless rats.
Inhibitory effect of the leukotriene B4 receptor antagonist against hypomagnesic diet-induced dermatitis in hairless rats.
Magnesium deficiency allergy-like crisis in hairless rats: a suggested model for inflammation studies.
[Histological study of magnesium deficiency dermatitis in hairless rats]
[Magnesium deficiency dermatitis--changes in leukotriene levels and effects of azelastine hydrochloride on the dermatitis and leukotriene B4]
Malnutrition
Effect of Protein Malnutrition on Skin Epidermis of Hairless Mice.
Medulloblastoma
OTX2 sustains a bivalent-like state of OTX2-bound promoters in medulloblastoma by maintaining their H3K27me3 levels.
The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma.
Meibomian Gland Dysfunction
Meibomian Gland Dysfunction Model in Hairless Mice Fed a Special Diet With Limited Lipid Content.
Melanoma
A novel hairless mouse model for malignant melanoma.
Anti-Melanogenic Effects of Korean Red Ginseng Oil in an Ultraviolet B-Induced Hairless Mouse Model.
Anti-tumor effects of various furocoumarins isolated from the roots, seeds and fruits of Angelica and Cnidium species under ultraviolet A irradiation.
Enhancement of nitric oxide and superoxide generations by alpha-tocopheryl succinate and its apoptotic and anticancer effects.
Experimental models for primary melanoma.
Highly pigmented Tg(Grm1) mouse melanoma develops non-pigmented melanoma cells in distant metastases.
In vitro and In vivo Antiproliferative Effect of a Combination of Ultraviolet-A and Alkoxy Furocoumarins Isolated from Umbelliferae Medicinal Plants, in Melanoma Cells.
Korean Red Ginseng extract ameliorates melanogenesis in humans and induces antiphotoaging effects in ultraviolet B-irradiated hairless mice.
Mapping of cutaneous melanoma by femtosecond laser-induced breakdown spectroscopy.
Melanoma genome sequencing reveals frequent PREX2 mutations.
Melanoma induction in a hairless mouse with short-term application of dimethylbenz[a]anthracene.
Melanomas of the scalp: is hair coverage preventing early diagnosis?
Non-thermal atmospheric pressure plasmas as a novel candidate for preventive therapy of melanoma.
Photocarcinogenesis: a review.
Potentiation of anti-cancer effect by intravenous administration of vesiculated alpha-tocopheryl hemisuccinate on mouse melanoma in vivo.
Production of melanomas from DMBA-induced "blue nevi" in hairless mice with ultraviolet light.
Proof-of-Concept Study of Multifunctional Hybrid Nanoparticle System Combined with NIR Laser Irradiation for the Treatment of Melanoma.
Retinoic acid metabolites exhibit biological activity in human keratinocytes, mouse melanoma cells and hairless mouse skin in vivo.
Role of ultraviolet radiation in the induction of melanocytic tumors in hairless mice following 7,12-dimethylbenz(a)anthracene application and ultraviolet irradiation.
Ultraviolet B-induced tumors in pigmented hairless mice, with an unsuccessful attempt to induce cutaneous melanoma.
Ultraviolet radiation and the development of non-melanoma and melanoma skin cancer: clinical and experimental evidence.
Melanoma, Experimental
B16 melanoma in hairless mice: a model for thermographic research.
Ingenol Disoxate: A Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers.
p21-Activated Kinase 4 Critically Regulates Melanogenesis via Activation of the CREB/MITF and ?-Catenin/MITF Pathways.
The Standardized Extract of Juniperus communis Alleviates Hyperpigmentation in Vivo HRM-2 Hairless Mice and in Vitro Murine B16 Melanoma Cells.
Melioidosis
Bioluminescent diagnostic imaging to characterize altered respiratory tract colonization by the burkholderia pseudomallei capsule mutant.
Memory Disorders
Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations.
Mental Retardation, X-Linked
Plant homeodomain fingers form a helping hand for transcription.
Metrorrhagia
Mutations in mice that influence natural killer (NK) cell activity.
Mouth Neoplasms
Integrated genomic analyses identify KDM1A's role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer.
Multiple Myeloma
Germline mutations in lysine specific demethylase 1 (LSD1/KDM1A) confer susceptibility to multiple myeloma.
Muscle Weakness
[The anti-synthetase syndrome]
Muscular Atrophy
Poikilodermia, anhidrosis, hairless body, neurogenic muscle atrophy, and recurrent hematuria: a new syndrome?
Myocarditis
Lyme borreliosis in selected strains and ages of laboratory mice.
Neoplasm Metastasis
Downregulation of histone demethylase JMJD1C inhibits colorectal cancer metastasis through targeting ATF2.
High KDM1A Expression Associated with Decreased CD8+T Cells Reduces the Breast Cancer Survival Rate in Patients with Breast Cancer.
KDM1A promotes tumor cell invasion by silencing TIMP3 in non-small cell lung cancer cells.
Knockdown of KDM1A suppresses tumour migration and invasion by epigenetically regulating the TIMP1/MMP9 pathway in papillary thyroid cancer.
Melanoma induction in a hairless mouse with short-term application of dimethylbenz[a]anthracene.
MiR-137-3p Inhibits Colorectal Cancer Cell Migration by Regulating a KDM1A-Dependent Epithelial-Mesenchymal Transition.
MYC Regulates PHF8, Which Promotes the Progression of Gastric Cancer by Suppressing miR-22-3p.
Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient.
Strain-specific metastatic phenotypes in pheochromocytoma allograft mice
Targeting LSD1 for acute myeloid leukemia (AML) treatment.
Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch.
The Jumonji Domain-Containing Histone Demethylase Homolog 1D/lysine Demethylase 7A (JHDM1D/KDM7A) Is an Epigenetic Activator of RHOJ Transcription in Breast Cancer Cells.
[Comparative proteomics of the serum in patients with nasopharyngeal carcinoma: a study with two-dimensional electrophoresis and MALDI-TOF-MS]
Neoplasms
(+)-2-(1-Hydroxyl-4-oxocyclohexyl) ethyl caffeate suppresses solar UV-induced skin carcinogenesis by targeting PI3K, ERK1/2, and p38.
3-Aminobenzamide can act as a cocarcinogen for ultraviolet light-induced carcinogenesis in mouse skin.
4-Hydroxy-3-methylbenzofuran-2-carbohydrazones as novel LSD1 inhibitors.
7,3'',4'' trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting COT and MKK4.
?-Santalol, a Skin Cancer Chemopreventive Agent with Potential to Target Various Pathways Involved in Photocarcinogenesis.
A comparison between the epidermal regenerative responses provoked by a skin irritant and a tumor promoter using anti-BrdUrd/DNA flow cytometry.
A definitive role of ornithine decarboxylase in photocarcinogenesis.
A new development in UVB phototherapy of psoriasis.
A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells.
A review of electroporation-based antitumor skin therapies and investigation of betulinic acid-loaded ointment.
A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy.
A STUDY OF TUMOR TYPES PRODUCED BY ULTRAVIOLET LIGHT IN HAIRLESS AND HAIRY MICE.
Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice.
Ability of PABA to protect mammalian skin from ultraviolet light-induced skin tumors and actinic damage.
Accelerated appearance of skin tumors in hairless mice by repeated UV irradiation with initial intense exposure and characterization of the tumors.
Action spectrum for photocarcinogenesis.
Activation of telomerase and its association with G1-phase of the cell cycle during UVB-induced skin tumorigenesis in SKH-1 hairless mouse.
ADA-07 Suppresses Solar Ultraviolet-Induced Skin Carcinogenesis by Directly Inhibiting TOPK.
Alterations in the expression of specific epidermal keratin markers in the hairless mouse by the topical application of the tumor promoters 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Aplasia cutis congenita of the scalp- what are the steps to be followed? Case report and review of the literature.
Arsenite-induced alterations of DNA photodamage repair and apoptosis after solar-simulation UVR in mouse keratinocytes in vitro.
Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation.
Assessment of skin irritation and molecular responses in rat skin exposed to nonane, dodecane and tetradecane.
ATX-S10(Na)-photodynamic therapy is less carcinogenic for mouse skin compared with ultraviolet B irradiation.
B16 melanoma in hairless mice: a model for thermographic research.
Breaking the LSD1/KDM1A addiction: therapeutic targeting of the epigenetic modifier in AML.
By the grace of peeling: the brace function of the stratum corneum in the protection from photo-induced keratinocyte carcinogenesis.
Cancer chemopreventive effect of orally administrated lupane-type triterpenoid on ultraviolet light B induced photocarcinogenesis of hairless mouse.
Cancer chemopreventive effects of oral feeding alpha-tocopherol on ultraviolet light B induced photocarcinogenesis of hairless mouse.
Cancer chemopreventive effects of Pinus Maritima bark extract on ultraviolet radiation and ultraviolet radiation-7,12,dimethylbenz(a)anthracene induced skin carcinogenesis of hairless mice.
Carcinogenesis induced by UVA (365-nm) radiation: the dose-time dependence of tumor formation in hairless mice.
Changes in mitochondrial DNA alter expression of nuclear encoded genes associated with tumorigenesis.
Characterization and histogenesis of tumors in the hairless mouse produced by low-dosage incremental ultraviolet radiation.
Chemical peeling by SA-PEG remodels photo-damaged skin: suppressing p53 expression and normalizing keratinocyte differentiation.
Chemical peeling with salicylic acid in polyethylene glycol vehicle suppresses skin tumour development in hairless mice.
Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis.
Chemopreventive effects of alpha-santalol on ultraviolet B radiation-induced skin tumor development in SKH-1 hairless mice.
Chemopreventive effects of sarcophine-diol on ultraviolet B-induced skin tumor development in SKH-1 hairless mice.
Chemopreventive Effects of Sarcotriol on Ultraviolet B-induced Skin Tumor Development in SKH-1 Hairless Mice.
Chemotherapeutic efficacy of topical celecoxib in a murine model of ultraviolet light B-induced skin cancer.
cis-9,trans-11-conjugated linoleic acid down-regulates phorbol ester-induced NF-kappaB activation and subsequent COX-2 expression in hairless mouse skin by targeting IkappaB kinase and PI3K-Akt.
Combined subcarcinogenic benzo[a]pyrene and UVA synergistically caused high tumor incidence and mutations in H-ras gene, but not p53, in SKH-1 hairless mouse skin.
Comparison of ultraviolet light-induced skin carcinogenesis and ornithine decarboxylase activity in sencar and hairless SKH-1 mice fed a constant level of dietary lipid varying in corn and coconut oil.
Conformational Dynamics Underlies Different Functions of Human KDM7 Histone Demethylases.
Curcumin Protects against UVB-Induced Skin Cancers in SKH-1 Hairless Mouse: Analysis of Early Molecular Markers in Carcinogenesis.
Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice.
Cytokeratin Profile of Basal Cell Carcinomas According to the Degree of Sun Exposure and to the Anatomical Localization.
Cytokine induction in hairless mouse and rat skin after topical application of the immune response modifiers imiquimod and S-28463.
Cytoplasmic translocation of nuclear LSD1 (KDM1A) in human hepatoma cells is induced by its inhibitors.
Design and synthesis of tranylcypromine derivatives as novel LSD1/HDACs dual inhibitors for cancer treatment.
Design, synthesis and biological activity of 3-oxoamino-benzenesulfonamides as selective and reversible LSD1 inhibitors.
Design, synthesis and biological activity of 4-(4-benzyloxy)phenoxypiperidines as selective and reversible LSD1 inhibitors.
Design, synthesis, and biological evaluation of 5-aminotetrahydroquinoline-based LSD1 inhibitors acting on Asp375.
Design, Synthesis, and Structure-Activity Relationship of Novel LSD1 Inhibitors Based on Pyrimidine-Thiourea Hybrids As Potent, Orally Active Antitumor Agents.
Detection of p53 and histopathological classification of skin tumours induced by halogen lamps in hairless mice.
Determination of the maximal carcinoma/normal skin ratio after HpD or m-THPC administration in Hairless mice (SKH-1) by fluorescence spectroscopy.
Determination of the maximal tumor/normal skin ratio after HpD or m-THPC administration in hairless mouse (SKh-1) by fluorescence spectroscopy--a non-invasive method.
Development of skin tumors in hairless mice after discontinuation of ultraviolet irradiation.
Development of UV-induced squamous cell carcinomas is suppressed in the absence of SPARC.
Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis.
Dietary Feeding of Opuntia Humifusa Inhibits UVB Radiation-Induced Carcinogenesis by Reducing Inflammation and Proliferation in Hairless Mouse Model.
Dietary feeding of proanthocyanidins from grape seeds prevents photocarcinogenesis in SKH-1 hairless mice: relationship to decreased fat and lipid peroxidation.
Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice.
Dietary Grape Seed Proanthocyanidins Inhibit UVB-Induced Cyclooxygenase-2 Expression and Other Inflammatory Mediators in UVB-Exposed Skin and Skin Tumors of SKH-1 Hairless Mice.
Dietary immunosuppressants do not enhance UV-induced skin carcinogenesis, and reveal discordance between p53-mutant early clones and carcinomas.
Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice.
Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models.
Discovery of tranylcypromine analogs with an acylhydrazone substituent as LSD1 inactivators: Design, synthesis and their biological evaluation.
Dose-dependent effects of UVB-induced skin carcinogenesis in hairless p53 knockout mice.
Dose-response on the chemopreventive effects of sarcophine-diol on UVB-induced skin tumor development in SKH-1 hairless mice.
Double-skin paddled superficial temporofascial flap for the reconstruction of full-thickness cheek defect.
Dual effects of human adipose tissue-derived mesenchymal stem cells in human lung adenocarcinoma A549 xenografts and colorectal adenocarcinoma HT-29 xenografts in mice.
Early events in UV carcinogenesis--DNA damage, target cells and mutant p53 foci.
Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells.
Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity.
Effect of crocetin on experimental skin tumors in hairless mice.
Effect of inositol hexaphosphate on the development of uvb-induced skin tumors in SKH1 hairless mice.
Effects of a High-Fat or High-Sucrose Diet on Ultraviolet B Irradiation-Induced Carcinogenesis and Tumor Growth in Melanin-Possessing Hairless Mice.
Effects of beta-carotene on chemically-induced skin tumors in HRA/Skh hairless mice.
Effects of beta-carotene on ultraviolet induced cancer formation in the hairless mouse skin.
Effects of dietary selenium on UVB-induced skin carcinogenesis and epidermal antioxidant status.
Effects of immunosuppressive therapy on the induction of skin tumors by ultraviolet irradiation in hairless mice.
Effects of intake of L-ascorbic acid on the incidence of dermal neoplasms induced in mice by ultraviolet light.
Effects of oral retinoid (vitamin A and etretinate) therapy on photocarcinogenesis in hairless mice.
Effects of ultraviolet-B and PUVA on ornithine decarboxylase activity, DNA synthesis, and protein kinase C activity in mouse skin.
Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation.
Enhancement of antioxidant and phase II enzymes by oral feeding of green tea polyphenols in drinking water to SKH-1 hairless mice: possible role in cancer chemoprevention.
Enhancement of u.v.-induced skin carcinogenesis in the hairless mouse by inoculation with cell-free extracts of skin tumours.
Epidermal proliferation but not quantity of DNA photodamage is correlated with UV-induced mouse skin carcinogenesis.
Epigallocatechin-3-gallate inhibits photocarcinogenesis through inhibition of angiogenic factors and activation of CD8+ T cells in tumors.
Exceptionally high protection of photocarcinogenesis by topical application of (--)-epigallocatechin-3-gallate in hydrophilic cream in SKH-1 hairless mouse model: relationship to inhibition of UVB-induced global DNA hypomethylation.
Experimental models for primary melanoma.
Experimental ultraviolet photocarcinogenesis: wavelength interactions and time-dose relationships.
EXPERIMENTALLY-INDUCED NEOPLASMS IN THE SKIN OF MICE. I. SINGLE-DOSE EFFECTS OF DMBA IN HAIRED, HAIRLESS, AND RHINO MICE.
Exploration of 5-cyano-6-phenylpyrimidin derivatives containing an 1,2,3-triazole moiety as potent FAD-based LSD1 inhibitors.
Exposure to chromium (VI) in the drinking water increases susceptibility to UV-induced skin tumors in hairless mice.
Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model.
Eyelid reconstruction in seven dogs using a split eyelid flap.
Fate of UVB-induced p53 mutations in SKH-hr1 mouse skin after discontinuation of irradiation: relationship to skin cancer development.
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics.
Fluorescence imaging and spectroscopy of ethyl nile blue A in animal models of (pre)malignancies.
Fractionation of a tumor-initiating UV dose introduces DNA damage-retaining cells in hairless mouse skin and renders subsequent TPA-promoted tumors non-regressing.
French maritime pine bark (Pinus maritima Lam.) extract (Flavangenol) prevents chronic UVB radiation-induced skin damage and carcinogenesis in melanin-possessing hairless mice.
Frequent p53 alterations but low incidence of ras mutations in UV-B-induced skin tumors of hairless mice.
Further insights into the SAR of ?-substituted cyclopropylamine derivatives as inhibitors of histone demethylase KDM1A.
Gene expression in skin tumors induced in hairless mice by chronic exposure to ultraviolet B irradiation.
Germline mutations in lysine specific demethylase 1 (LSD1/KDM1A) confer susceptibility to multiple myeloma.
Grape seed proanthocyanidines and skin cancer prevention: inhibition of oxidative stress and protection of immune system.
Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch(+/-) Mice.
Hairless regulates p53 target genes to exert tumor suppressive functions in glioblastoma.
High KDM1A Expression Associated with Decreased CD8+T Cells Reduces the Breast Cancer Survival Rate in Patients with Breast Cancer.
High MHC class I expression correlates with slow growth in UV-induced skin carcinomas in hairless mice.
High-throughput virtual screening identifies novel N'-(1-phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors.
Histogenesis and progression in ultraviolet light-induced tumors in hairless mice.
Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage.
Histone demethylase KDM7A controls androgen receptor activity and tumor growth in prostate cancer.
Histone demethylase KDM7A is required for stem cell maintenance and apoptosis inhibition in breast cancer.
Histone Demethylase KDM7A Regulates Androgen Receptor Activity, and Its Chemical Inhibitor TC-E 5002 Overcomes Cisplatin-Resistance in Bladder Cancer Cells.
Histone demethylase LSD1 controls the phenotypic plasticity of cancer cells.
Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers.
Hyperbaric hydrogen therapy: a possible treatment for cancer.
Hypertrichosis lanuginosa acquisita. Report of a case and review of the literature.
Identification of an mtDNA mutation hot spot in UV-induced mouse skin tumors producing altered cellular biochemistry.
Identification of papillomaviral DNA sequences in hairless mouse tumours induced by ultraviolet irradiation.
Identification of selective and reversible LSD1 inhibitors with anti-metastasis activity by high-throughput docking.
Identifying the Novel Inhibitors of Lysine specific demethylase 1 (LSD1) Combining Pharmacophore-Based and Structure-Based Virtual Screening.
Immunodeficiency and reticulum cell sarcoma in mice segregating for HRS/J and SJL/J genes.
Immunological phenomena in harmless mice during experimental carcinogenesis induced with long-term topical application of 7, 12-dimethylbenzanthracene (DMBA).
In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy.
Induction and modulation of lung tumors: genomic and transcriptional alterations in cigarette smoke-exposed mice.
Induction of hair regrowth in the alopecia site of IFN-gamma knockout mice by allografting and IFN-gamma injection into the transplantation site.
Induction of skin tumors in hairless mice by a single exposure to UV radiation.
Ingenol Disoxate: A Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers.
Inhibition of neutrophil elastase suppresses the development of skin tumors in hairless mice.
Inhibition of skin tumor promoter-caused induction of epidermal ornithine decarboxylase in SENCAR mice by polyphenolic fraction isolated from green tea and its individual epicatechin derivatives.
Inhibitory effect of glycolic acid on ultraviolet B-induced c-fos expression, AP-1 activation and p53-p21 response in a human keratinocyte cell line.
Inhibitory effect of topical applications of nondenatured soymilk on the formation and growth of UVB-induced skin tumors.
Inhibitory effects of orally administered green tea, black tea, and caffeine on skin carcinogenesis in mice previously treated with ultraviolet B light (high-risk mice): relationship to decreased tissue fat.
Inhibitory effects of silk protein, sericin on UVB-induced acute damage and tumor promotion by reducing oxidative stress in the skin of hairless mouse.
Initiating carcinogen, triethylenemelamine, induces micronuclei in skin target cells.
Intake of high-fat diet stimulates the risk of ultraviolet radiation-induced skin tumors and malignant progression of papillomas to carcinoma in SKH-1 hairless mice.
Integrated genomic analyses identify KDM1A's role in cell proliferation via modulating E2F signaling activity and associate with poor clinical outcome in oral cancer.
Interaction of phospholipids, retinoids and PMA with calcium, phospholipid-dependent protein kinase-catalyzed reaction in skin.
Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice.
Investigating the Binding Mode of Reversible LSD1 Inhibitors Derived from Stilbene Derivatives by 3D-QSAR, Molecular Docking, and Molecular Dynamics Simulation.
Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model.
Irradiance-dependent UVB Photocarcinogenesis.
Jmjd1c is dispensable for healthy adult hematopoiesis and Jak2V617F-driven myeloproliferative disease initiation in mice.
KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer.
KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer.
KDM1A microenvironment, its oncogenic potential, and therapeutic significance.
KDM1A Promotes Immunosuppression in Hepatocellular Carcinoma by Regulating PD-L1 through Demethylating MEF2D.
Kdm1a promotes SCLC progression by transcriptionally silencing the tumor suppressor Rest.
KDM1A promotes tumor cell invasion by silencing TIMP3 in non-small cell lung cancer cells.
Knockdown of KDM1A suppresses tumour migration and invasion by epigenetically regulating the TIMP1/MMP9 pathway in papillary thyroid cancer.
Knocking down LSD1 inhibits the stemness features of colorectal cancer stem cells.
Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors.
Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors.
Lichen Planopilaris Developing at the Margins of a Sebaceous Nevus of Jadassohn: Co-existence or Etiologic Association?
Localisation and accumulation of a new carotenoporphyrin in two primary tumour models.
Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling.
Low incidence of p53 mutations in UVA (365-nm)-induced skin tumors in hairless mice.
LPE-1, an orally active pyrimidine derivative, inhibits growth and mobility of human esophageal cancers by targeting LSD1.
LSD1 dual function in mediating epigenetic corruption of the vitamin D signaling in prostate cancer.
LSD1 sustains estrogen-driven endometrial carcinoma cell proliferation through the PI3K/AKT pathway via di-demethylating H3K9 of cyclin D1.
Luteolin inhibits protein kinase C(epsilon) and c-Src activities and UVB-induced skin cancer.
Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/?-catenin pathway by down-regulating Dickkopf-1 (DKK1).
Lysine-specific histone demethylase 1 (LSD1): A potential molecular target for tumor therapy.
Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ER?-dependent and -independent manners.
MicroRNA-329 inhibits cell proliferation and tumor growth while facilitates apoptosis via negative regulation of KDM1A in gastric cancer.
miR-101 regulates cell proliferation and apoptosis by targeting KDM1A in diffuse large B cell lymphoma.
MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A.
MiR-137-3p Inhibits Colorectal Cancer Cell Migration by Regulating a KDM1A-Dependent Epithelial-Mesenchymal Transition.
miR-329 suppresses the growth and motility of neuroblastoma by targeting KDM1A.
Modified submental platysmal adipomyofascial flap: is it a reliable alternate reconstructive option for small- to mid-sized defects especially in male patients with oral/oropharyngeal cancer?
Modulating drug resistance by targeting BCRP/ABCG2 using retrovirus-mediated RNA interference.
Modulation of light-induced skin tumors by N-acetylcysteine and/or ascorbic acid in hairless mice.
Modulation of tumor promotion in mouse skin by the food additive citral (3,7-dimethyl-2,6-octadienal).
Molecular Mechanisms Underlying Chemopreventive Activities of Glycyrrhizic Acid against UVB-Radiation-Induced Carcinogenesis in SKH-1 Hairless Mouse Epidermis.
Monobenzone, a Novel and Potent KDM1A Inhibitor, Suppresses Migration of Gastric Cancer Cells.
Morphological changes in BFU hairless mice injected by homologous tumours -- Ehrlich's and Brno carcinomas.
Mosaic Activating Mutations in FGFR1 Cause Encephalocraniocutaneous Lipomatosis.
Multivariate flow cytometry of epidermal regeneration provoked by a skin irritant and a tumor promoter.
Mutations in BALB mitochondrial DNA induce CCL20 up-regulation promoting tumorigenic phenotypes.
Mutations in cancer genes of UV-induced skin tumors of hairless mice.
Mutations in ras oncogenes: rare events in ultraviolet B radiation-induced mouse skin tumorigenesis.
MYC Regulates PHF8, Which Promotes the Progression of Gastric Cancer by Suppressing miR-22-3p.
Narrow-band UVB induces more carcinogenic skin tumors than broad-band UVB through the formation of cyclobutane pyrimidine dimer.
Natural killer cell activity during UVR-induced skin tumor formation in the Skh hairless mouse.
New Mechanism of Bone Cancer Pain: Tumor Tissue-Derived Endogenous Formaldehyde Induced Bone Cancer Pain via TRPV1 Activation.
Nitric Oxide Donor Exisulind Is an Effective Inhibitor of Murine Photocarcinogenesis(†).
Nitrogen mustard (mechlorethamine) and UVB photocarcinogenesis: a dose response effect.
Non-equilibrium atmospheric pressure plasmas modulate cell cycle-related gene expressions in melanocytic tumors of RET-transgenic mice.
Non-thermal atmospheric pressure plasmas as a novel candidate for preventive therapy of melanoma.
Nondenatured soy extracts reduce UVB-induced skin damage via multiple mechanisms.
Nonpeptidic Propargylamines as Inhibitors of Lysine Specific Demethylase 1 (LSD1) with Cellular Activity.
Novel combination of histone methylation modulators with therapeutic synergy against acute myeloid leukemia in vitro and in vivo.
Novel dual LSD1/HDAC6 inhibitors for the treatment of multiple myeloma.
Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans.
Nuclear GSK3? promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22.
Oestrogen receptor-beta signalling protects against transplanted skin tumour growth in the mouse.
Olive Leaf Extract and Its Main Component Oleuropein Prevent Chronic Ultraviolet B Radiation-Induced Skin Damage and Carcinogenesis in Hairless Mice.
Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia.
Oral administration of dimethylarsinic acid, a main metabolite of inorganic arsenic, in mice promotes skin tumorigenesis initiated by dimethylbenz(a)anthracene with or without ultraviolet B as a promoter.
Oral administration of Polypodium leucotomos delays skin tumor development and increases epidermal p53 expression and the anti-oxidant status of UV-irradiated hairless mice.
ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia.
Over-expression of lysine-specific demethylase 1 predicts tumor progression and poor prognosis in human esophageal cancer.
Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
p53 mutations in cutaneous lesions induced in the hairless mouse by a solar ultraviolet light simulator.
p53 Mutations in hairless SKH-hr1 mouse skin tumors induced by a solar simulator.
Papillomavirus-associated fibropapillomas of red deer ( Cervus elaphus ).
Passive cigarette smoke exposure inhibits ultraviolet light B-induced skin tumors in SKH-1 hairless mice by blocking the nuclear factor kappa B signalling pathway.
Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice.
Persisting long-term effects of a single carcinogenic dose of methylnitrosourea on epidermal growth in mice.
Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration.
Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes.
PHF8 upregulation contributes to autophagic degradation of E-cadherin, epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma.
Photocarcinogenesis: measuring the reproducibility of a biologic response to ultraviolet radiation exposure in mice.
Photochemical genotoxicity and photochemical carcinogenesis--two sides of a coin?
Photodynamic therapy of chemically- and ultraviolet B radiation-induced murine skin papillomas by chloroaluminum phthalocyanine tetrasulfonate.
Photodynamic therapy of murine skin tumors using Photofrin-II.
Photodynamic therapy using topically applied hypericin: Comparative effect with methyl-aminolevulinic acid on UV induced skin tumours.
Photophysical and photobiological properties of 3-carbethoxypsoralen.
Photoprotective effect of superoxide-scavenging antioxidants against ultraviolet radiation-induced chronic skin damage in the hairless mouse.
Pilot studies evaluating the lung tumor yield in cigarette smoke-exposed mice.
Polychlorinated biphenyls (PCBs): mutagenicity and carcinogenicity.
Polyinosinic-polycytidylic acid: inhibition of cell proliferation in carcinogen-treated epidermis and in carcinogen-induced skin tumors in mice.
Pretreatment with long-wave ultraviolet light inhibits ultraviolet-induced skin tumor development in hairless mice.
Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin.
Probing the binding mode and unbinding mechanism of LSD1 inhibitors by combined computational methods.
Proliferating trichilemmal cyst with focal calcification.
Protection against 12-O-tetradecanoylphorbol-13-acetate-caused inflammation in SENCAR mouse ear skin by polyphenolic fraction isolated from green tea.
Protection by black tea and green tea against UVB and UVA + B induced skin cancer in hairless mice.
Protection by tea against UV-A + B-induced skin cancers in hairless mice.
Protective Effect of Dermal Brimonidine Applications Against UV Radiation-induced Skin Tumors, Epidermal Hyperplasia and Cell Proliferation in the Skin of Hairless Mice.
Protective effect of hyperpigmented skin on UV-mediated cutaneous cancer development.
Protective Effect of Inositol Hexaphosphate Against UVB Damage in HaCaT Cells and Skin Carcinogenesis in SKH1 Hairless Mice.
Protective effect of topically applied conjugated hexadienes against ultraviolet radiation-induced chronic skin damage in the hairless mouse.
Protective effects of silymarin against photocarcinogenesis in a mouse skin model.
Protoporphyrin IX fluorescence kinetics in UV-induced tumours and normal skin of hairless mice after topical application of 5-aminolevulinic acid methyl ester.
Protoporphyrin IX fluorescence photobleaching during ALA-mediated photodynamic therapy of UVB-induced tumors in hairless mouse skin.
Quercetin prevents UV-induced local immunosuppression, but does not affect UV-induced tumor growth in SKH-1 hairless mice.
Rapid body weight gain increases the risk of UV radiation-induced skin carcinogenesis in SKH-1 hairless mice.
Ras p21 farnesylation in ultraviolet B radiation-induced tumors in the skin of SKH-1 hairless mice.
Reduction of UV-induced skin tumors in hairless mice by selective COX-2 inhibition.
Relation of antioxidants and level of dietary lipid to epidermal lipid peroxidation and ultraviolet carcinogenesis.
Relationship between the hairless gene and susceptibility to induced pulmonary tumors in mice.
Repeated treatments with ingenol mebutate for prophylaxis of UV-induced squamous cell carcinoma in hairless mice.
Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71.
Reticuloses and epidermal tumors in hairless mice after topical skin applications of cantharidin and asiaticoside.
Reticulum cell neoplasms in normal and benzene treated hairless mice.
Role for tumour necrosis factor-alpha receptors in ultraviolet-induced skin tumours.
Role of ultraviolet radiation in the induction of melanocytic tumors in hairless mice following 7,12-dimethylbenz(a)anthracene application and ultraviolet irradiation.
S/RV Cri-ba, a hairless mouse strain sensitive to skin tumorigenesis by suboptimal doses of 7,12-dimethylbenz[a]anthracene, initiation-promotion and two stage promotion protocols.
Sensitivity of HRA/Skh hairless mice to initiation/promotion of skin tumors by chemical treatment.
Serially expanded flap use to treat large hairless scalp lesions.
Sex differences and pathology status correlated to the toxicity of some common carcinogens in experimental skin carcinoma.
Significant association between KDM1A promoter hypomethylation and colorectal cancer in Han Chinese.
Simulated solar light-induced p53 mutagenesis in SKH-1 mouse skin: a dose-response assessment.
SKHIN/Sprd, a new genetically defined inbred hairless mouse strain for UV-induced skin carcinogenesis studies.
Skin tumor development after UV irradiation and photodynamic therapy is unaffected by short-term pretreatment with 5-fluorouracil, imiquimod and calcipotriol. An experimental hairless mouse study.
Skin tumor development and keratin expression in different experimental models. Relation to inducing agent and target tissue structure.
Specificity of epidermal chalone extracts for human epidermoid tumour cells in vitro: a preliminary report.
Spontaneous and induced tumors in haired and hairless strain HR mice.
Squamous cell tumors induced in hairless mice with ultraviolet light.
Stage-specific alterations of cyclin expression during UVB-induced murine skin tumor development.
Steady-state mRNA levels of interleukin-1, integrins, cJun, and cFos in hairless mouse skin during short-term chronic UV exposure and the effect of topical tretinoin.
Strand-specific removal of cyclobutane pyrimidine dimers from the p53 gene in the epidermis of UVB-irradiated hairless mice.
Studies on the role of C-type viruses in the development of epithelial tumors induced with DMBA.
Studying skin tumourigenesis and progression in immunocompetent hairless SKH1-hr mice using chronic 7,12-dimethylbenz(a)anthracene topical applications to develop a useful experimental skin cancer model.
Suppression of squamous cell carcinoma in hairless mice by dietary nutrient variation.
Synergistic antitumor effect of 5-fluorouracil with the novel LSD1 inhibitor ZY0511 in colorectal cancer.
Synergistic topical photoprotection by a combination of the iron chelator 2-furildioxime and sunscreen.
Synthesis and biological evaluation of novel (E)-N'-(2,3-dihydro-1H-inden-1-ylidene) benzohydrazides as potent LSD1 inhibitors.
Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.
Synthesis, structure-activity relationship studies and biological characterization of new [1,2,4]triazolo[1,5-a]pyrimidine-based LSD1/KDM1A inhibitors.
Systemic photodynamic therapy with aminolaevulinic acid delays the appearance of ultraviolet-induced skin tumours in mice.
Tannins protect against skin tumor promotion induced by ultraviolet-B radiation in hairless mice.
Target separation and antitumor metastasis activity of sesquiterpene-based lysine-specific demethylase 1 inhibitors from zedoary turmeric oil.
Targeting LSD1 for acute myeloid leukemia (AML) treatment.
Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch.
Temperature over tumors in hairless mice.
The carcinogenic effect of UVA irradiation.
The chemopreventive efficacies of nonsteroidal anti-inflammatory drugs: the relationship of short-term biomarkers to long-term skin tumor outcome.
The early effects of a single application of acetone and various doses of 7,12-dimethylbenz(alpha)anthracene on CD-1 and hairless mouse epidermis. A cell kinetic study of so-called initiation and complete carcinogenesis (initiation plus promotion) in chemical skin tumor induction.
The effect of occlusive and unocclusive exposure to xylene and benzene on skin irritation and molecular responses in hairless rats.
The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin.
The effect ofdietary phenobarbital on the induction of skin tumors in hairless mice with 7, 12-dimethylbenz(a)anthracene.
The effects of topical L-selenomethionine on protection against UVB-induced skin cancer when given before, during, and after UVB exposure.
The histone demethylase lysine-specific demethylase-1-mediated epigenetic silence of KLF2 contributes to gastric cancer cell proliferation, migration, and invasion.
The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent.
The Jumonji Domain-Containing Histone Demethylase Homolog 1D/lysine Demethylase 7A (JHDM1D/KDM7A) Is an Epigenetic Activator of RHOJ Transcription in Breast Cancer Cells.
The rapid induction of cancers in the hairless mouse utilizing the principle of photoaugmentation.
The role of KLF4 in UVB-induced murine skin tumor development and its correlation with cyclin D1, p53, and p21(Waf1/Cip1) in epithelial tumors of the human skin.
The role of orally administered dimethylarsinic acid, a main metabolite of inorganic arsenics, in the promotion and progression of UVB-induced skin tumorigenesis in hairless mice.
The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice.
The sensitivity of the skin of hairless mice to chemical carcinogenesis.
Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
Three-dimensional printed optical phantoms with customized absorption and scattering properties.
Time and dose dependence of acceptance of UV-induced syngeneic tumor implants in chronically UV-exposed hairless mice.
Topical AC-11 abates actinic keratoses and early squamous cell cancers in hairless mice exposed to Ultraviolet A (UVA) radiation.
Topical urocanic acid enhances UV-induced tumour yield and malignancy in the hairless mouse.
Transdermal delivery of adriamycin to transplanted ehrlich ascites tumor in mice.
Treatment with topical khellin in combination with ultraviolet A or solar-simulated radiation is carcinogenic to lightly pigmented hairless mice.
Tumor development in backcross mice segregated with respect to the hairless and the pink-eye genes.
Tumor-promoting role of TGF?1 signaling in ultraviolet B-induced skin carcinogenesis is associated with cutaneous inflammation and lymph node migration of dermal dendritic cells.
Tumorigenesis and carcinogenesis studies of a number of insulation oils and fluids on hairless and SENCAR mice with special reference to skin tumours and malignant lymphomas.
Tumorigenesis by short-wave ultraviolet A: papillomas versus squamous cell carcinomas.
Tumors induced in hairless mice by DNA from human malignant cells.
Tumour induction in mouse epidermal cells irradiated by hot particles.
Tumour promotion by TCDD in skin of HRS/J hairless mice.
Ultraviolet B radiation increases steady-state mRNA levels for cytokines and integrins in hairless mouse skin: modulation by topical tretinoin.
Ultraviolet B-induced tumors in pigmented hairless mice, with an unsuccessful attempt to induce cutaneous melanoma.
Ultraviolet carcinogenesis in the hairless mouse skin. Influence of the sunscreen 2-ethylhexyl-p-methoxycinnamate.
Ultraviolet radiation-induced inflammation activates ?-catenin signaling in mouse skin and skin tumors.
Ultraviolet radiation-induced non-melanoma skin cancer in the Crl:SKH1:hr-BR hairless mouse: augmentation of tumor multiplicity by chlorophyllin and protection by indole-3-carbinol.
UVA irradiation increases the incidence of epithelial tumors in UVB-irradiated hairless mice.
UVA tanning devices interact with solar-simulated UV radiation in skin tumor development in hairless mice.
UVA-induced tumours in pigmented hairless mice and the carcinogenic risks of tanning with UVA.
Whole-Exome Sequencing Validates a Preclinical Mouse Model for the Prevention and Treatment of Cutaneous Squamous Cell Carcinoma.
XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.
[Cytophotometric measurements of DNA and histone protein content in experimentally induced skin tumors of the rat and hairless mouse. II]
[Degenerative changes in schwannoma (neurilemmoma)]
[Encephalocraniocutaneous lipomatosis]
[Function of histone demethylasehistone lysine-specific demethylase 1A in tumor initiation and progression].
[Intra-oral cancer: immediate reconstruction using a free radial forearm flap]
[Morphology of experimentally induced skin tumors in the rat and hairless mouse. I]
[Several characteristics of tissue cultured human esophageal cell lines]
Neoplasms, Radiation-Induced
Tumour induction in mouse epidermal cells irradiated by hot particles.
Neoplasms, Squamous Cell
Topical AC-11 abates actinic keratoses and early squamous cell cancers in hairless mice exposed to Ultraviolet A (UVA) radiation.
Nervous System Malformations
Encephalocraniocutaneous Lipomatosis Without Ocular Malformations.
Neuroblastoma
MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A.
miR-329 suppresses the growth and motility of neuroblastoma by targeting KDM1A.
MiR-542-3p Suppresses Neuroblastoma Cell Proliferation and Invasion by Downregulation of KDM1A and ZNF346.
Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
The hairless promoter is differentially regulated by thyroid hormone in keratinocytes and neuroblastoma cells.
Neurocutaneous Syndromes
Encephalocraniocutaneous lipomatosis accompanied by the formation of bone cysts: Harboring clues to pathogenesis?
Encephalocraniocutaneous Lipomatosis Without Ocular Malformations.
Nevus
Apoptosis in abortive hair follicular components in the organoid nevus.
Becker's nevus.
Ceruminous adenoma (ceruminoma) arising in a nevus sebaceus of Jadassohn within the external auditory canal of a 3 year-old boy - A case report.
Complete spontaneous regression of multiple basal cell carcinomas in the basal cell nevus syndrome: the possible role of transepithelial elimination.
Desmoplastic giant congenital nevus with progressive depigmentation.
Desmoplastic hairless hypopigmented nevus (DHHN). A distinct variant of giant melanocytic nevus.
Desmoplastic hairless hypopigmented nevus.
Desmoplastic Hypopigmented Hairless Nevus: A Variant with Progressive Depigmentation, Induration, and Overgrowth.
Diagnostic challenge of a proliferative nodule in a desmoplastic hairless hypopigmented nevus.
Eccrine Poroma Arising within Nevus Sebaceous.
Encephalocraniocutaneous lipomatosis accompanied by the formation of bone cysts: Harboring clues to pathogenesis?
Encephalocraniocutaneous Lipomatosis Without Ocular Malformations.
Encephalocraniocutaneous Lipomatosis.
Encephalocraniocutaneous Lipomatosis: Haberland Syndrome.
Mosaic Activating Mutations in FGFR1 Cause Encephalocraniocutaneous Lipomatosis.
Nevus psiloliparus: a distinct fatty tissue nevus.
Nevus sebaceus.
Paired hairless and hairy nevi: a further example of twin spotting?
The effect of sebocytes cultured from nevus sebaceus on hair growth.
Trilogy Revisited: A Case Report of Co-Existing Nevus Sebaceous with Syringocystadenoma Papilliferum and Tubular Apocrine Adenoma.
Whorled hairless nevus of the scalp, linear hyperpigmentation, and telangiectatic nevi of the lower limbs: a novel variant of the "phacomatosis complex".
Nevus, Pigmented
Desmoplastic giant congenital nevus with progressive depigmentation.
Desmoplastic hairless hypopigmented nevus (DHHN). A distinct variant of giant melanocytic nevus.
Desmoplastic Hypopigmented Hairless Nevus: A Variant with Progressive Depigmentation, Induration, and Overgrowth.
Novel hairless RET-transgenic mouse line with melanocytic nevi and anagen hair follicles.
Nevus, Sebaceous of Jadassohn
Ceruminous adenoma (ceruminoma) arising in a nevus sebaceus of Jadassohn within the external auditory canal of a 3 year-old boy - A case report.
Noonan Syndrome
Noonan-like syndrome with loose anagen hair: a new syndrome?
Obesity
Association of Diet With Skin Histological Features in UV-B-Exposed Mice.
The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity.
Onychomycosis
[Epidemiological and clinical profile of superficial mycoses in the Monastir region (Tunisia). Retrospective study (1991-1994) of 3578 cases]
Osteoporosis
Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBP? and canonical Wnt signalling.
Possibility of Alveolar Bone Promoting Enhancement by Using Lipophilic and/or Hydrophilic Zinc Related Compounds in Zinc-Deficient Osteoporosis Rats.
Therapeutic potential of Liuwei Dihuang pill against KDM7A and Wnt/?-catenin signaling pathway in diabetic nephropathy-related osteoporosis.
Otitis Externa
Effects of ear type, sex, age, body weight, and climate on temperatures in the external acoustic meatus of dogs.
Ovarian Neoplasms
Inhibition of DNA methyltransferases, histone deacetylases and lysine-specific demethylase-1 suppresses the tumorigenicity of the ovarian cancer ascites cell line SKOV3.
Pancreatic Neoplasms
KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer.
Papilloma
All-trans retinoic acid protects against conversion of chemically induced and ultraviolet B radiation-induced skin papillomas to carcinomas.
Are FDA-Approved Sunscreen Components Effective in Preventing Solar UV-Induced Skin Cancer?
Determination of endogenous porphyrins and the maximal HpD tumor/normal skin ratio in SKH-1 hairless mice by light induced fluorescence spectroscopy.
Differential expression of glutathione-s-transferase isozymes in murine and human skin tumors.
Grape seed proanthocyanidines and skin cancer prevention: inhibition of oxidative stress and protection of immune system.
Identification of papillomaviral DNA sequences in hairless mouse tumours induced by ultraviolet irradiation.
In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy.
Intake of high-fat diet stimulates the risk of ultraviolet radiation-induced skin tumors and malignant progression of papillomas to carcinoma in SKH-1 hairless mice.
Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds.
MOCA and some proposed substitutes (Cyanacure, Conacure, Polacure 740M and Ethacure 300) as two-stage skin carcinogens in HRA/Skh hairless mice.
Papillomas (warts) in hairless mice. Mus musculus and Peromyscus maniculatus gambeli.
Polychlorinated biphenyls (PCBs): mutagenicity and carcinogenicity.
Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N-acetyltransferase.
Sensitivity of HRA/Skh hairless mice to initiation/promotion of skin tumors by chemical treatment.
Skin tumor development and keratin expression in different experimental models. Relation to inducing agent and target tissue structure.
Skin-tumour-promoting activity of processed bidi tobacco in hairless S/RV Cri-ba mice.
The National Toxicology Program rodent bioassay: designs, interpretations, and scientific contributions.
XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.
[In vitro methods for phototoxicity and photocarcinogenicity testing of drugs]
Parakeratosis
Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice.
Normal Vulvar Histology: Variation by Site.
Paralysis
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice.
Overt Infection with Chronic Bee Paralysis Virus (CBPV) in Two Honey Bee Colonies.
Sphenoid mucocele: an uncommon complication of a rare condition.
Topical treatment of cutaneous herpes simplex virus infection in hairless mice with (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
Xylotubercidin against herpes simplex virus type 2 in mice.
Paraproteinemias
Germline mutations in lysine specific demethylase 1 (LSD1/KDM1A) confer susceptibility to multiple myeloma.
Parasitic Diseases
Cutaneous transcriptome analysis in NIH hairless mice.
Perinatal Death
Partial rescue of epithelial phenotype in integrin beta4 null mice by a keratin-5 promoter driven human integrin beta4 transgene.
Peritonitis
Factors Affecting the Welfare of Unweaned Dairy Calves Destined for Early Slaughter and Abattoir Animal-Based Indicators Reflecting Their Welfare On-Farm.
Photophobia
[The significance of the columar structure of the stratum corneum for the effect of light on the skin]
Photosensitivity Disorders
Photochemotherapy: a new promising chemical derivative.
Photodynamic therapy of chemically- and ultraviolet B radiation-induced murine skin papillomas by chloroaluminum phthalocyanine tetrasulfonate.
Psoralen photosensitization and plasma and cutaneous beta-carotene concentrations in hairless mice.
Skin photosensitization with topical hypericin in hairless mice.
Porphyria, Hepatoerythropoietic
1599: first iconographic description of hepatoerythropoietic porphyria.
Porphyrias
Pleiotropic effect of the gene hairless on hepatotoxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in mice.
[Animal experiment model of the effect of ultraviolet irradiation on hexachlorobenzene-induced porphyria]
Port-Wine Stain
Cutaneous side effects from laser treatment of the skin: skin cancer, scars, wounds, pigmentary changes, and purpura--use of pulsed dye laser, copper vapor laser, and argon laser.
[Developmental abnormalities and nevi of the scalp].
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes.
Prostatic Hyperplasia
Clinical significance of miRNA host gene promoter methylation in prostate cancer.
Prostatic Neoplasms
A Rhodium(III)-Based Inhibitor of Lysine-Specific Histone Demethylase 1 as an Epigenetic Modulator in Prostate Cancer Cells.
Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence.
AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase.
Histone demethylase KDM7A controls androgen receptor activity and tumor growth in prostate cancer.
Inhibition of Recombining Binding Protein Suppressor of Hairless (RBPJ) Impairs the Growth of Prostate Cancer.
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.
[Function of histone demethylasehistone lysine-specific demethylase 1A in tumor initiation and progression].
Pruritus
Apocrine hidrocystoma arising from nevus sebaceous on the scalp.
Dietary deficiencies of unsaturated fatty acids and starch cause atopic dermatitis-like pruritus in hairless mice.
Effect of loratadine on mouse models of atopic dermatitis associated pruritus.
Pimecrolimus (Elidel, SDZ ASM 981)--preclinical pharmacologic profile and skin selectivity.
Psoriasis
Absorption, distribution, and excretion of 8-methoxypsoralen in HRA/Skh mice.
An animal model for screening drugs for antipsoriatic properties using hydroxyapatite to isolate DNA rapidly from the epidermis.
An animal model for screening topical and systemic drugs for potential use in the treatment of psoriasis.
Investigation of the absorption of hypericin into the skin of hairless mice.
Pharmacokinetics of the poly-gamma-glutamyl metabolites of methotrexate in skin and other tissues of rats and hairless mice.
The potential of the essential fatty acid-deficient hairless rat as a psoriasis screening model for topical anti-proliferative drugs.
Topical drug effects on normal and proliferating epidermal cell models.
Topical methotrexate therapy for psoriasis.
Pulmonary Fibrosis
Lysine-specific demethylase-1 regulates fibroblast activation in pulmonary fibrosis via TGF-?1/Smad3 pathway.
Purpura
Effects of calmodulin antagonists and anesthetics on the skin lesions induced by 2-chloroethylethyl sulfide.
Pyoderma
Superficial pyoderma, secondary to the hairless nature of the breed.
Radiodermatitis
Altered Immune Cell Proportions in the Radiodermatitis Induced Hairless Mice-1 (HR-1).
Early diagnosis of radiodermatitis using lactate dehydrogenase isozymes in hairless mice (SKH1-hr).
Expression profiling of radiation-induced genes in radiodermatitis of hairless mice.
ID3 mediates X-ray-induced apoptosis of keratinocytes through the regulation of ?-catenin.
Reperfusion Injury
In vivo analysis of microvascular reperfusion injury in striated muscle and skin.
Rickets
Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene.
Interactions of the vitamin D receptor with the corepressor hairless: analysis of hairless mutants in atrichia with papular lesions.
Ligand-independent regulation of the hairless promoter by vitamin D receptor.
The alopecias associated with vitamin D-dependent rickets type IIA and with hairless gene mutations: a comparative clinical, histologic, and immunohistochemical study.
Sarcoma
Catalytic inhibition of KDM1A in Ewing sarcoma is insufficient as a therapeutic strategy.
In vivo evaluation of the lysine-specific demethylase (KDM1A/LSD1) inhibitor SP-2577 (Seclidemstat) against pediatric sarcoma preclinical models: A report from the Pediatric Preclinical Testing Consortium (PPTC).
The sensitivity of the skin of hairless mice to chemical carcinogenesis.
Sarcoma, Ewing
Catalytic inhibition of KDM1A in Ewing sarcoma is insufficient as a therapeutic strategy.
Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.
Seizures
Encephalocraniocutaneous lipomatosis accompanied by the formation of bone cysts: Harboring clues to pathogenesis?
Severe Combined Immunodeficiency
miR-17-92 cluster promotes cholangiocarcinoma growth: evidence for PTEN as downstream target and IL-6/Stat3 as upstream activator.
Skin Abnormalities
Molecular basis for the rhino Yurlovo (hr(rhY)) phenotype: severe skin abnormalities and female reproductive defects associated with an insertion in the hairless gene.
Skin Diseases
Blockade of atopic dermatitis-like skin lesions by DA-9102, a natural medicine isolated from Actinidia arguta, in the Mg-deficiency induced dermatitis model of hairless rats.
Dermatosis in magnesium-deficient hairless rats: effects of steroidal and non-steroidal anti-inflammatory drugs.
Dermatosis of hairless rats fed a hypomagnesic diet--pathology and immunology.
Evaluation of cross-reacting anti-human antibodies in the euthymic hairless guinea pig model (HGP) suggests that the HGP may be a model for the study of proliferative skin disease.
Generalized alopecic and cystic dermatosis in a cat: a counterpart to the hairless mouse phenotype or a unique congenital dermatosis?
Magnesium deficiency allergy-like crisis in hairless rats: a suggested model for inflammation studies.
Magnesium-deficient hairless rat: spleen cells mitogenic responses and variations in hormonal status.
New model of a scaling dermatosis: induction of hyperproliferation in hairless mice with eicosa-5,8,11-trienoic acid.
Noninvolvement of histamine and prostaglandins in the dermatosis of magnesium-deficient hairless rats.
SCH 47112, a novel staurosporine derivative, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and epidermal hyperplasia in hairless mouse skin.
Skin inflammation induced by hypomagnesaemia in the rat.
The dermatosis of hairless rats fed a hypomagnesaemic diet. I. Course, clinical features and inhibition by drugs.
The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active.
Skin Neoplasms
(+)-2-(1-Hydroxyl-4-oxocyclohexyl) ethyl caffeate suppresses solar UV-induced skin carcinogenesis by targeting PI3K, ERK1/2, and p38.
A panel of criteria for comprehensive assessment of severity of ultraviolet B radiation-induced non-melanoma skin cancers in SKH-1 mice.
A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy.
Accelerated induction of skin cancers by ultraviolet radiation in hairless mice treated with immunosuppressive agents.
Bromelain as a skin cancer preventive in hairless mice.
Celecoxib, a cyclooxygenase 2 inhibitor as a potential chemopreventive to UV-induced skin cancer: a study in the hairless mouse model.
Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis.
Chemopreventive effects of sarcophine-diol on ultraviolet B-induced skin tumor development in SKH-1 hairless mice.
Chemopreventive Effects of Sarcotriol on Ultraviolet B-induced Skin Tumor Development in SKH-1 Hairless Mice.
Curcumin Protects against UVB-Induced Skin Cancers in SKH-1 Hairless Mouse: Analysis of Early Molecular Markers in Carcinogenesis.
Cutaneous side effects from laser treatment of the skin: skin cancer, scars, wounds, pigmentary changes, and purpura--use of pulsed dye laser, copper vapor laser, and argon laser.
Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis.
Dietary fats and UV radiation-induced skin cancer in the hairless mouse.
Differential hairless mouse strain-specific susceptibility to skin cancer and sunburn.
Dual role of SIRT1 in UVB-induced skin tumorigenesis.
Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells.
Effects of topical and oral vitamin E on pigmentation and skin cancer induced by ultraviolet irradiation in Skh:2 hairless mice.
Effects of topical L-selenomethionine with topical and oral vitamin E on pigmentation and skin cancer induced by ultraviolet irradiation in Skh:2 hairless mice.
Epigallocatechin-3-gallate inhibits photocarcinogenesis through inhibition of angiogenic factors and activation of CD8+ T cells in tumors.
Frequent p53 alterations but low incidence of ras mutations in UV-B-induced skin tumors of hairless mice.
Further evidence against a direct genotoxic mode of action for arsenic-induced cancer.
Honokiol, a phytochemical from the Magnolia plant, inhibits photocarcinogenesis by targeting UVB-induced inflammatory mediators and cell cycle regulators: development of topical formulation.
Interaction between ultraviolet A and ultraviolet B radiations in skin cancer induction in hairless mice.
Localisation and accumulation of a new carotenoporphyrin in two primary tumour models.
Loss of Fas-ligand expression in mouse keratinocytes during UV carcinogenesis.
Multiple large-surface photodynamic therapy sessions with topical or systemic aminolevulinic acid and blue light in UV-exposed hairless mice.
Mutations in cancer genes of UV-induced skin tumors of hairless mice.
Parthenolide sensitizes ultraviolet (UV)-B-induced apoptosis via protein kinase C-dependent pathways.
Polychlorinated biphenyls (PCBs): mutagenicity and carcinogenicity.
Potentiating effect of dietary vitamin A on photocarcinogenesis in hairless mice.
Protection against UV photocarcinogenesis by fabric materials.
Protection by black tea and green tea against UVB and UVA + B induced skin cancer in hairless mice.
Protection by tea against UV-A + B-induced skin cancers in hairless mice.
Protective effect of sanguinarine on ultraviolet B-mediated damages in SKH-1 hairless mouse skin: implications for prevention of skin cancer.
Protoporphyrin IX fluorescence kinetics and localization after topical application of ALA pentyl ester and ALA on hairless mouse skin with UVB-induced early skin cancer.
Skin cancer chemoprevention by ?-santalol.
Studying skin tumourigenesis and progression in immunocompetent hairless SKH1-hr mice using chronic 7,12-dimethylbenz(a)anthracene topical applications to develop a useful experimental skin cancer model.
Substitution of equally carcinogenic UV-A for UV-B irradiations lowers epidermal thymine dimer levels during skin cancer induction in hairless mice.
Sunless skin tanning with dihydroxyacetone delays broad-spectrum ultraviolet photocarcinogenesis in hairless mice.
Sunscreens for delay of ultraviolet induction of skin tumors.
The role of KLF4 in UVB-induced murine skin tumor development and its correlation with cyclin D1, p53, and p21(Waf1/Cip1) in epithelial tumors of the human skin.
Time and dose dependence of acceptance of UV-induced syngeneic tumor implants in chronically UV-exposed hairless mice.
TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation.
Tumorigenesis and carcinogenesis studies of a number of insulation oils and fluids on hairless and SENCAR mice with special reference to skin tumours and malignant lymphomas.
Ultraviolet radiation-induced non-melanoma skin cancer in the Crl:SKH1:hr-BR hairless mouse: augmentation of tumor multiplicity by chlorophyllin and protection by indole-3-carbinol.
Use of Fractional CO2 Laser Decreases the Risk of Skin Cancer Development During Ultraviolet Exposure in Hairless Mice.
UV Light B-Mediated Inhibition of Skin Catalase Activity Promotes Gr-1(+)CD11b(+) Myeloid Cell Expansion.
UV-induced skin cancer in a hairless mouse model.
Wavelength dependence of skin cancer induction by ultraviolet irradiation of albino hairless mice.
Skin Ulcer
Congenital absence of scalp skin and herpes simplex virus. A case report.
Sleep Deprivation
Influence of sleep deprivation and morphine on the expression of inducible nitric oxide synthase and cyclooxygenase-2 in skin of hairless mice.
Is lack of sleep capable of inducing DNA damage in aged skin?
Small Cell Lung Carcinoma
LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.
Sporotrichosis
Antibody raised against extracellular proteinases of Sporothrix schenckii in S. schenckii inoculated hairless mice.
Stomach Neoplasms
Capsaicin: A "hot" KDM1A/LSD1 inhibitor from peppers.
Design, synthesis, and biological evaluation of novel dual inhibitors targeting lysine specific demethylase 1 (LSD1) and histone deacetylases (HDAC) for treatment of gastric cancer.
MicroRNA-329 inhibits cell proliferation and tumor growth while facilitates apoptosis via negative regulation of KDM1A in gastric cancer.
Monobenzone, a Novel and Potent KDM1A Inhibitor, Suppresses Migration of Gastric Cancer Cells.
The histone demethylase lysine-specific demethylase-1-mediated epigenetic silence of KLF2 contributes to gastric cancer cell proliferation, migration, and invasion.
Triazole-dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration.
USP28 contributes to the proliferation and metastasis of gastric cancer.
Sunburn
Attenuation of DNA damage in the dermis and epidermis of the albino hairless mouse by chronic exposure to ultraviolet-A and -B radiation.
Comparative potency of broad-band and narrow-band phototherapy sources to induce edema, sunburn cells and urocanic acid photoisomerization in hairless mouse skin.
Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
Differential hairless mouse strain-specific susceptibility to skin cancer and sunburn.
Dorsal skin reactions to sunlight and artificial ultraviolet light in hairless descendants of Mexican hairless dogs.
Effect of Artocarpus communis Extract on UVB Irradiation-Induced Oxidative Stress and Inflammation in Hairless Mice.
Effect of glutathione depletion on sunburn cell formation in the hairless mouse.
Effects of indomethacin on sunburn and suntan reactions in hairless descendants of Mexican hairless dogs.
In vitro antioxidant and in vivo photoprotective effects of an association of bioflavonoids with liposoluble vitamins.
Inhibitory effects of tea and caffeine on UV-induced carcinogenesis: relationship to enhanced apoptosis and decreased tissue fat.
Interaction of UVB-absorbing sunscreen ingredients with cutaneous molecules may alter photoimmune protection.
Mice drinking goji berry juice (Lycium barbarum) are protected from UV radiation-induced skin damage via antioxidant pathways.
Noninvasive Assessment of UV-induced Skin Damage: Comparison of Optical Measurements to Histology and MMP Expression.
Photoprotective effect of esterified glutathione against ultraviolet B-induced sunburn cell formation in the hairless mice.
Photoprotective effects of methoxycinnamidopropyl polysilsesquioxane.
Protection by zinc against UVA- and UVB-induced cellular and genomic damage in vivo and in vitro.
The sunburn cell in hairless mouse epidermis: quantitative studies with UV-A radiation and mono- and bifunctional psoralens.
Topical tocopherol acetate reduces post-UVB, sunburn-associated erythema, edema, and skin sensitivity in hairless mice.
Tetanus
Genetically determined disproportion between primary and secondary tetanus antitoxin responses and proliferative reactions in lymph nodes regional to the site of antigen injection: C57L/J compared with haired and hairless HRS/J mice.
Transcutaneous vaccination using a hydrogel patch induces effective immune responses to tetanus and diphtheria toxoid in hairless rat.
Thrombosis
A new model for quantitative in vivo microscopic analysis of thrombus formation and vascular recanalisation: the ear of the hairless (hr/hr) mouse.
Differential effects of endogenous, phyto and synthetic cannabinoids on thrombogenesis and platelet activity.
Effect of mutalysin II on vascular recanalization after thrombosis induction in the ear of the hairless mice model.
In vivo analysis of antithrombotic effectiveness of recombinant hirudin on microvascular thrombus formation and recanalization.
Intravital Microscopy and Thrombus Induction in the Earlobe of a Hairless Mouse.
Microvascular consequences of thrombosis in small venules: an in vivo microscopic study using a novel model in the ear of the hairless mouse.
The thrombolytic action of a proteolytic fraction (P1G10) from Carica candamarcensis.
[Antithrombotic and thrombolytic effectiveness of rhirudin in mcrovessels]
Thyroid Cancer, Papillary
Knockdown of KDM1A suppresses tumour migration and invasion by epigenetically regulating the TIMP1/MMP9 pathway in papillary thyroid cancer.
Tinea
Clinical and epidemiological aspects of various forms of fungal infections caused by Trichophyton tonsurans.
Experimental Trichophyton Mentagrophytes infection in hairless and haired dogs.
Tinea of vellus hair: an indication for systemic antifungal therapy.
[Epidemiological and clinical profile of superficial mycoses in the Monastir region (Tunisia). Retrospective study (1991-1994) of 3578 cases]
[Epidemiology, etiology and clinical presentation of dermatophytosis in Pernambuco, 1995-2005]
[Tinea of the hairless skin. Quality Assurance Committee of the German Society of Dermatology and the Professional Organization of German Dermatologists e. V.]
[Treatment of trichophytosis of the hairless skin with the specific hyposensitization method]
Tinea Capitis
Trichoscopy as a useful method to differentiate tinea capitis from alopecia areata in children at Zagazig University Hospitals.
[Epidemiological and clinical profile of superficial mycoses in the Monastir region (Tunisia). Retrospective study (1991-1994) of 3578 cases]
Tinea Versicolor
[Epidemiological and clinical profile of superficial mycoses in the Monastir region (Tunisia). Retrospective study (1991-1994) of 3578 cases]
Tongue, Fissured
A scanning electron microscopic study of fissured tongue.
Triple Negative Breast Neoplasms
KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer.
ORY-1001, a KDM1A inhibitor, inhibits proliferation, and promotes apoptosis of triple negative breast cancer cells by inactivating androgen receptor.
Tuberculosis
Modulation of delayed-type hypersensitivity responses in hairless guinea pigs by peptides derived from enkephalin.
Tubular Sweat Gland Adenomas
Trilogy Revisited: A Case Report of Co-Existing Nevus Sebaceous with Syringocystadenoma Papilliferum and Tubular Apocrine Adenoma.
Tumor Virus Infections
Evaluation of 6-azauridine and 5-iododeoxyuridine in the treatment of experimental viral infections.
Urethral Stricture
One-stage penile/preputial island flap urethroplasty for urethral stricture.
Surgical outcome of urethroplasty using penile circular fasciocutaneous flap for anterior urethral stricture.
Urinary Bladder Neoplasms
Further evidence against a direct genotoxic mode of action for arsenic-induced cancer.
Histone Demethylase KDM7A Regulates Androgen Receptor Activity, and Its Chemical Inhibitor TC-E 5002 Overcomes Cisplatin-Resistance in Bladder Cancer Cells.
Uterine Cervical Neoplasms
Histone Deacetylation Regulated by KDM1A to Suppress DACT1 in Proliferation and Migration of Cervical Cancer.
Vaccinia
Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines.
Cutaneous infections of mice with vaccinia or cowpox viruses and efficacy of cidofovir.
Enhanced efficacy of cidofovir combined with vaccinia immune globulin in treating progressive cutaneous vaccinia virus infections in immunosuppressed hairless mice.
Evaluation of imiquimod for topical treatment of vaccinia virus cutaneous infections in immunosuppressed hairless mice.
Topical cidofovir is more effective than is parenteral therapy for treatment of progressive vaccinia in immunocompromised mice.
Topical treatment of cutaneous vaccinia virus infections in immunosuppressed hairless mice with selected antiviral substances.
Varicose Ulcer
Hair-follicle Transplant Into Chronic Ulcers: A New Graft Concept.
Virus Diseases
Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines.
Design of 9-beta-D-arabinofuranosyladenine (ara-A) transdermal delivery system for animal studies: regulation of drug concentration in vivo.
Effect of immune serum on the establishment of herpes simplex virus infection in trigeminal ganglia of hairless mice.
Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice.
Enhanced efficacy of cidofovir combined with vaccinia immune globulin in treating progressive cutaneous vaccinia virus infections in immunosuppressed hairless mice.
Established latent herpes simplex virus infections of mice not affected by adenosine monophosphate treatment.
Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - An animal model of smallpox.
Immune response and latent infection after topical treatment of herpes simplex virus infection in hairless mice.
Latent herpes simplex virus infections in sensory ganglia of hairless mice prevented by acycloguanosine.
Optimization of in vitro flux through hairless mouse skin of cidofovir, a potent nucleotide analog.
Orofacial herpes simplex virus infection in hairless mice: latent virus in trigeminal ganglia after topical antiviral treatment.
Phosphonoacetic acid-resistant herpes simplex virus infection in hairless mice.
Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.
Topical treatment of cutaneous herpes simplex virus infection in hairless mice with (E)-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.
Topical treatment of cutaneous vaccinia virus infections in immunosuppressed hairless mice with selected antiviral substances.
[Experimental herpes simplex virus infection of the skin of hairless mice]
[Foot-and-mouth disease and its differential diagnoses].
Vitamin A Deficiency
Vitamin A deficiency and the induction of cutaneous toxicity in murine skin by TCDD.
Vitiligo
Melanogenesis from topical mechlorethamine and analogues in skin of hairless mice and in vitiligo.
Wound Infection
Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus-Based Wound Infection Model in SKH1 Mice.
[histone h3]-dimethyl-l-lysine9 demethylase deficiency
Lysine-Specific Demethylase-1 Deficiency Increases Agonist Signaling Via the Mineralocorticoid Receptor.
Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation.