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Information on EC 1.14.11.64 - glutarate dioxygenase

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IUBMB Comments
Requires iron(II). The enzyme, characterized from the bacteria Escherichia coli and Pseudomonas putida, participates in L-lysine degradation in many bacteria. It provides an alternative route for L-glutarate degradation that does not proceed via CoA-activated intermediates.
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The enzyme appears in viruses and cellular organisms
Synonyms
csiD, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2
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