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Information on EC 1.14.11.54 - mRNA N1-methyladenine demethylase

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IUBMB Comments
Contains iron(II). Catalyses oxidative demethylation of mRNA N1-methyladenine. The enzyme is also involved in alkylation repair in DNA .
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Word Map
  • 1.14.11.54
  • paraneoplastic
  • pokeweed
  • anti-yo
  • anna-1
  • anti-il-6
  • cd45ra
  • cell-restricted
  • medicine
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
N1-methyladenine in mRNA
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=
adenine in mRNA
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Synonyms
pca-1, prostate cancer antigen-1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
N1-methyladenine in mRNA + 2-oxoglutarate + O2 = adenine in mRNA + formaldehyde + succinate + CO2
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