Disease on EC 1.14.11.33 - DNA oxidative demethylase
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Breast Neoplasms
CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer.
Carcinogenesis
Analysis of differentially expressed genes in human rectal carcinoma using suppression subtractive hybridization.
Carcinogenesis
Fluorescence Probes for ALKBH2 Allow the Measurement of DNA Alkylation Repair and Drug Resistance Responses.
Carcinogenesis
The oxidative demethylase ALKBH3 marks hyperactive gene promoters in human cancer cells.
Carcinoma
A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression.
Carcinoma
ALKBH2, a novel AlkB homologue, contributes to human bladder cancer progression by regulating MUC1 expression.
Carcinoma
ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals.
Carcinoma in Situ
A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression.
Carcinoma in Situ
ALKBH2, a novel AlkB homologue, contributes to human bladder cancer progression by regulating MUC1 expression.
Carcinoma, Non-Small-Cell Lung
Down-regulation of ALKBH2 increases cisplatin sensitivity in H1299 lung cancer cells.
Colorectal Neoplasms
ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-?B pathway.
dna oxidative demethylase deficiency
Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming?.
Glioblastoma
The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells.
Hodgkin Disease
Epigenetic Loss of m1A RNA Demethylase ALKBH3 in Hodgkin Lymphoma Targets Collagen Conferring Poor Clinical Outcome.
Intellectual Disability
Recessive Truncating Mutations in ALKBH8 Cause Intellectual Disability and Severe Impairment of Wobble Uridine Modification.
Leukemia
ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-?B pathway.
Lung Neoplasms
ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer.
Lung Neoplasms
Down-regulation of ALKBH2 increases cisplatin sensitivity in H1299 lung cancer cells.
Lung Neoplasms
TP53 gene status is a critical determinant of phenotypes induced by ALKBH3 knockdown in non-small cell lung cancers.
Neoplasm Metastasis
Indenone derivatives as inhibitor of human DNA dealkylation repair enzyme AlkBH3.
Neoplasms
A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression.
Neoplasms
AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells.
Neoplasms
ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy.
Neoplasms
ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-?B pathway.
Neoplasms
ALKBH2, a novel AlkB homologue, contributes to human bladder cancer progression by regulating MUC1 expression.
Neoplasms
ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals.
Neoplasms
ALKBH8 promotes bladder cancer growth and progression through regulating the expression of survivin.
Neoplasms
Anti-Tumor Effect of AlkB Homolog 3 Knockdown in Hormone- Independent Prostate Cancer Cells.
Neoplasms
Association of AlkB homolog 3 expression with tumor recurrence and unfavorable prognosis in hepatocellular carcinoma.
Neoplasms
DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation.
Neoplasms
Fluorescence Monitoring of the Oxidative Repair of DNA Alkylation Damage by ALKBH3, a Prostate Cancer Marker.
Neoplasms
Fluorescence Probes for ALKBH2 Allow the Measurement of DNA Alkylation Repair and Drug Resistance Responses.
Neoplasms
Human ALKBH3-induced m1A demethylation increases the CSF-1 mRNA stability in breast and ovarian cancer cells.
Neoplasms
Indenone derivatives as inhibitor of human DNA dealkylation repair enzyme AlkBH3.
Neoplasms
The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants.
Neoplasms
The oxidative demethylase ALKBH3 marks hyperactive gene promoters in human cancer cells.
Neoplasms
TP53 regulates human AlkB homologue 2 expression in glioma resistance to Photofrin-mediated photodynamic therapy.
Neoplasms
Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs.
Prostatic Hyperplasia
Anti-Tumor Effect of AlkB Homolog 3 Knockdown in Hormone- Independent Prostate Cancer Cells.
Prostatic Neoplasms
ALKBH3, a human AlkB homologue, contributes to cell survival in human non-small-cell lung cancer.
Prostatic Neoplasms
Anti-Tumor Effect of AlkB Homolog 3 Knockdown in Hormone- Independent Prostate Cancer Cells.
Prostatic Neoplasms
Fluorescence Monitoring of the Oxidative Repair of DNA Alkylation Damage by ALKBH3, a Prostate Cancer Marker.
Prostatic Neoplasms
The oxidative demethylase ALKBH3 marks hyperactive gene promoters in human cancer cells.
Squamous Cell Carcinoma of Head and Neck
ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy.
Urinary Bladder Neoplasms
A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression.
Urinary Bladder Neoplasms
ALKBH2, a novel AlkB homologue, contributes to human bladder cancer progression by regulating MUC1 expression.
Urinary Bladder Neoplasms
ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals.
Urinary Bladder Neoplasms
ALKBH8 promotes bladder cancer growth and progression through regulating the expression of survivin.
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