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BRENDA support

Information on EC 1.14.11.16 - peptide-aspartate beta-dioxygenase

for references in articles please use BRENDA:EC1.14.11.16

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IUBMB Comments

Requires Fe2+. Some vitamin K-dependent coagulation factors, as well as synthetic peptides based on the structure of the first epidermal growth factor domain of human coagulation factor IX or X, can act as acceptors.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
factor inhibiting hif, aspartyl beta-hydroxylase, aspartyl (asparaginyl) beta-hydroxylase, factor-inhibiting hypoxia-inducible factor, factor inhibiting hypoxia-inducible factor, hif asparaginyl hydroxylase, aspartyl/asparaginyl beta-hydroxylase, aspartate beta-hydroxylase, aspartyl (asparaginyl)-beta-hydroxylase, human aspartyl (asparaginyl) beta-hydroxylase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
peptide-L-aspartate + 2-oxoglutarate + O2 = peptide-3-hydroxy-L-aspartate + succinate + CO2
show the reaction diagram
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