Reference on EC 1.13.99.1 - inositol oxygenase
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Charalampous, F.C.
Biochemical studies on inositol. V. Purification and properties of the enzyme that cleaves inositol to D-glucuronic acid
J. Biol. Chem.
234
220-227
1959
Rattus norvegicus
Moskala, R.; Reddy, C.C.; Minard, R.D.; Hamilton, G.A.
An oxygen-18 tracer investigation of the mechanism of myo-inositol oxygenase
Biochem. Biophys. Res. Commun.
99
107-113
1981
Sus scrofa
Reddy, C.C.; Hamilton, G.A.
Activation of homogeneous preparations of hog kidney myo-inositol oxygenase by quinolinic acid and ferrous ions
Biochem. Biophys. Res. Commun.
100
1389-1395
1981
Sus scrofa
Reddy, C.C.; Swan, J.S.; Hamilton, G.A.
myo-Inositol oxygenase from hog kidney. I. Purification and characterization of the oxygenase and of an enzyme complex containing the oxygenase and D-glucuronate reductase
J. Biol. Chem.
156
8510-8518
1981
Sus scrofa
Koller, F.; Hoffmann-Ostenhof, O.
myo-Inositol oxygenase from rat kidneys. I: Purification by affinity chromatography; physical and catalytic properties
Hoppe-Seyler's Z. Physiol. Chem.
360
507-513
1979
Rattus norvegicus
Koller, F.; Koller, E.
Affinity chromatography of myo-inositol oxygenase from rat kidney by means of an insoluble D-galacto-hexodialdose derivative
J. Chromatogr.
283
191-197
1984
Rattus norvegicus
Graham, M.N.; Mantle, T.J.
Partial purification of myo-inositol oxygenase from ox kidney by using phenyl-Sepharose
Biochem. Soc. Trans.
13
481
1985
Bos taurus
-
Koller, F.; Koller, E.
myo-inositol oxygenase from rat kidneys. Substrate-dependent oligomerization
Eur. J. Biochem.
193
421-427
1990
Rattus norvegicus
Reddy, C.C.; Pierzchala, P.A.; Hamilton, G.A.
myo-Inositol oxygenase from hog kidney. II. Catalytic properties of the homogeneous enzyme
J. Biol. Chem.
256
8519-8524
1981
Sus scrofa
Naber, N.I.; Swan, J.S.; Hamilton, G.A.
L-myo-Inosose-1 as a probable intermediate in the reaction catalyzed by myo-inositol oxygenase
Biochemistry
25
7201-7207
1986
Sus scrofa
Arner, R.J.; Prabhu, K.S.; Thompson, J.T.; Hildenbrandt, G.R.; Liken, A.D.; Reddy, C.C.
myo-Inositol oxygenase: molecular cloning and expression of a unique enzyme that oxidizes myo-inositol and D-chiro-inositol
Biochem. J.
360
313-320
2001
Sus scrofa (Q8WN98), Sus scrofa
Arner, R.J.; Prabhu, K.S.; Reddy, C.C.
Molecular cloning, expression, and characterization of myo-inositol oxygenase from mouse, rat, and human kidney
Biochem. Biophys. Res. Commun.
324
1386-1392
2004
Rattus norvegicus (Q9QXN4), Mus musculus (Q9QXN5), Mus musculus, Homo sapiens (Q9UGB7), Homo sapiens
Prabhu, K.S.; Arner, R.J.; Vunta, H.; Reddy, C.C.
Up-regulation of human myo-inositol oxygenase by hyperosmotic stress in renal proximal tubular epithelial cells
J. Biol. Chem.
280
19895-19901
2005
Homo sapiens (Q9UGB7), Homo sapiens
Lorence, A.; Chevone, B.I.; Mendes, P.; Nessler, C.L.
myo-Inositol oxygenase offers a possible entry point into plant ascorbate biosynthesis
Plant Physiol.
134
1200-1205
2004
Arabidopsis thaliana (Q8H1S0)
Kanter, U.; Becker, M.; Friauf, E.; Tenhaken, R.
Purification, characterization and functional cloning of inositol oxygenase from Cryptococcus
Yeast
20
1317-1329
2003
Sporopachydermia lactativora (Q70GL3), Sporopachydermia lactativora
Brown, P.M.; Caradoc-Davies, T.T.; Dickson, J.M.; Cooper, G.J.; Loomes, K.M.; Baker, E.N.
Purification, crystallization and preliminary crystallographic analysis of mouse myo-inositol oxygenase
Acta Crystallogr. Sect. F
F62
811-813
2006
Mus musculus
Arner, R.J.; Prabhu, K.S.; Krishnan, V.; Johnson, M.C.; Reddy, C.C.
Expression of myo-inositol oxygenase in tissues susceptible to diabetic complications
Biochem. Biophys. Res. Commun.
339
816-820
2006
Homo sapiens, Mus musculus, Sus scrofa
Xing, G.; Hoffart, L.M.; Diao, Y.; Prabhu, K.S.; Arner, R.J.; Reddy, C.C.; Krebs, C.; Bollinger, J.M.
A coupled dinuclear iron cluster that is perturbed by substrate binding in myo-inositol oxygenase
Biochemistry
45
5393-5401
2006
Mus musculus
Xing, G.; Barr, E.W.; Diao, Y.; Hoffart, L.M.; Prabhu, K.S.; Arner, R.J.; Reddy, C.C.; Krebs, C.; Bollinger, J.M.
Oxygen activation by a mixed-valent, diiron(II/III) cluster in the glycol cleavage reaction catalyzed by myo-inositol oxygenase
Biochemistry
45
5402-5412
2006
Mus musculus
Kim, S.H.; Xing, G.; Bollinger, J.M.; Krebs, C.; Hoffman, B.M.
Demonstration by 2H ENDOR spectroscopy that myo-inositol binds via an alkoxide bridge to the mixed-valent diiron center of myo-inositol oxygenase
J. Am. Chem. Soc.
128
10374-10375
2006
Mus musculus
Kanter, U.; Usadel, B.; Guerineau, F.; Li, Y.; Pauly, M.; Tenhaken, R.
The inositol oxygenase gene family of Arabidopsis is involved in the biosynthesis of nucleotide sugar precursors for cell-wall matrix polysaccharides
Planta
221
243-254
2005
Arabidopsis thaliana
Nayak, B.; Xie, P.; Akagi, S.; Yang, Q.; Sun, L.; Wada, J.; Thakur, A.; Danesh, F.R.; Chugh, S.S.; Kanwar, Y.S.
Modulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience
Proc. Natl. Acad. Sci. USA
102
17952-17957
2005
Mus musculus
Brown, P.M.; Caradoc-Davies, T.T.; Dickson, J.M.; Cooper, G.J.; Loomes, K.M.; Baker, E.N.
Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism
Proc. Natl. Acad. Sci. USA
103
15032-15037
2006
Mus musculus
Xing, G.; Diao, Y.; Hoffart, L.M.; Barr, E.W.; Prabhu, K.S.; Arner, R.J.; Reddy, C.C.; Krebs, C.; Bollinger, J.M.
Evidence for C-H cleavage by an iron-superoxide complex in the glycol cleavage reaction catalyzed by myo-inositol oxygenase
Proc. Natl. Acad. Sci. USA
103
6130-6135
2006
Mus musculus
Thorsell, A.G.; Persson, C.; Voevodskaya, N.; Busam, R.D.; Hammarstroem, M.; Graeslund, S.; Graeslund, A.; Hallberg, B.M.
Structural and biophysical characterization of human myo-inositol oxygenase
J. Biol. Chem.
283
15209-15216
2008
Homo sapiens
Moon, T.S.; Yoon, S.H.; Lanza, A.M.; Roy-Mayhew, J.D.; Prather, K.L.
Production of glucaric acid from a synthetic pathway in recombinant Escherichia coli
Appl. Environ. Microbiol.
75
589-595
2009
Mus musculus (Q9QXN5)
Bollinger, J.M.; Diao, Y.; Matthews, M.L.; Xing, G.; Krebs, C.
myo-Inositol oxygenase: a radical new pathway for O(2) and C-H activation at a nonheme diiron cluster
Dalton Trans.
2009
905-914
2009
Mammalia, Mus musculus
Lu, Y.; Liu, C.; Miao, X.; Xu, K.; Wu, X.; Liu, C.
Increased expression of myo-inositol oxygenase is involved in the tubulointerstitial injury of diabetic nephropathy
Exp. Clin. Endocrinol. Diabetes
117
257-265
2009
Rattus norvegicus
Siddique, S.; Endres, S.; Atkins, J.M.; Szakasits, D.; Wieczorek, K.; Hofmann, J.; Blaukopf, C.; Urwin, P.E.; Tenhaken, R.; Grundler, F.M.; Kreil, D.P.; Bohlmann, H.
Myo-inositol oxygenase genes are involved in the development of syncytia induced by Heterodera schachtii in Arabidopsis roots
New Phytol.
184
457-472
2009
Arabidopsis thaliana (O82200), Arabidopsis thaliana (Q8H1S0), Arabidopsis thaliana (Q8L799), Arabidopsis thaliana (Q9FJU4)
Endres, S.; Tenhaken, R.
Myoinositol oxygenase controls the level of myoinositol in Arabidopsis, but does not increase ascorbic acid
Plant Physiol.
149
1042-1049
2009
Arabidopsis thaliana (O82200), Arabidopsis thaliana (Q8H1S0), Arabidopsis thaliana (Q8L799), Arabidopsis thaliana (Q9FJU4)
Yang, B.; Hodgkinson, A.; Millward, B.; Demaine, A.
Polymorphisms of myo-inositol oxygenase gene are associated with type 1 diabetes mellitus
J. Diabetes Complicat.
24
404-408
2010
Homo sapiens
Alford, S.R.; Rangarajan, P.; Williams, P.; Gillaspy, G.E.
myo-Inositol oxygenase is required for responses to low energy conditions in Arabidopsis thaliana
Front. Plant Sci.
3
69
2012
Arabidopsis thaliana
Senthilraja, P.; Paul Aime, N.; Manikandaprabhu, S.; Prakash, M.
Computational screening and docking analysis of natural compounds derived from mangrove plant against type-2 diabetes, myo-inositol oxygenase enzyme (MIOX)
Int. J. Pharm. Sci. Rev. Res.
20
158-161
2013
Homo sapiens
-
Nayak, B.; Kondeti, V.K.; Xie, P.; Lin, S.; Viswakarma, N.; Raparia, K.; Kanwar, Y.S.
Transcriptional and post-translational modulation of myo-inositol oxygenase by high glucose and related pathobiological stresses
J. Biol. Chem.
286
27594-27611
2011
Mus musculus
Siddique, S.; Endres, S.; Sobczak, M.; Radakovic, Z.; Fragner, L.; Grundler, F.; Weckwerth, W.; Tenhaken, R.; Bohlmann, H.
Myo-inositol oxygenase is important for the removal of excess myo-inositol from syncytia induced by Heterodera schachtii in Arabidopsis roots
New Phytol.
201
476-85
2014
Arabidopsis thaliana
Gaut, J.P.; Crimmins, D.L.; Ohlendorf, M.F.; Lockwood, C.M.; Griest, T.A.; Brada, N.A.; Hoshi, M.; Sato, B.; Hotchkiss, R.S.; Jain, S.; Ladenson, J.H.
Development of an immunoassay for the kidney-specific protein myo-inositol oxygenase, a potential biomarker of acute kidney injury
Clin. Chem.
60
747-757
2014
Mus musculus (Q9QXN5), Mus musculus, Homo sapiens (Q9UGB7), Homo sapiens, Mus musculus C57BL/6 (Q9QXN5)
Liu, Y.; Gong, X.; Wang, C.; Du, G.; Chen, J.; Kang, Z.
Production of glucaric acid from myo-inositol in engineered Pichia pastoris
Enzyme Microb. Technol.
91
8-16
2016
Komagataella phaffii (C4QZH8), Mus musculus (Q9QXN5), Mus musculus, Komagataella phaffii GS115 (C4QZH8)
Shi, F.; Dong, Y.; Zhang, Y.; Yang, X.; Qiu, D.
Overexpression of the PeaT1 elicitor gene from Alternaria tenuissima improves drought tolerance in rice plants via interaction with a myo-inositol oxygenase
Front. Plant Sci.
8
970
2017
Oryza sativa (Q5Z8T3), Oryza sativa
Zhan, M.; Usman, I.M.; Sun, L.; Kanwar, Y.S.
Disruption of renal tubular mitochondrial quality control by myo-inositol oxygenase in diabetic kidney disease
J. Am. Soc. Nephrol.
26
1304-1321
2015
Mus musculus (Q9QXN5), Homo sapiens (Q9UGB7)
Tominaga, T.; Dutta, R.K.; Joladarashi, D.; Doi, T.; Reddy, J.K.; Kanwar, Y.S.
Transcriptional and translational modulation of myo-inositol oxygenase (Miox) by fatty acids implications in renal tubular injury induced in obesity and diabetes
J. Biol. Chem.
291
1348-1367
2016
Sus scrofa (Q8WN98), Rattus norvegicus (Q9QXN4), Mus musculus (Q9QXN5), Homo sapiens (Q9UGB7), Mus musculus CD1 (Q9QXN5)
Sun, L.; Dutta, R.K.; Xie, P.; Kanwar, Y.S.
myo-Inositol oxygenase overexpression accentuates generation of reactive oxygen species and exacerbates cellular injury following high glucose ambience a new mechanism relevant to the pathogenesis of diabetic nephropathy
J. Biol. Chem.
291
5688-5707
2016
Sus scrofa (Q8WN98)
Siddique, S.; Endres, S.; Sobczak, M.; Radakovic, Z.; Fragner, L.; Grundler, F.; Weckwerth, W.; Tenhaken, R.; Bohlmann, H.
Myo-inositol oxygenase is important for the removal of excess myo-inositol from syncytia induced by Heterodera schachtii in Arabidopsis roots
New Phytol.
201
476-485
2014
Arabidopsis thaliana (O82200), Arabidopsis thaliana (Q8H1S0), Arabidopsis thaliana (Q8L799), Arabidopsis thaliana (Q9FJU4), Arabidopsis thaliana Col-0 (O82200), Arabidopsis thaliana Col-0 (Q8H1S0), Arabidopsis thaliana Col-0 (Q8L799), Arabidopsis thaliana Col-0 (Q9FJU4)
Chen, C.; Sun, X.; Duanmu, H.; Yu, Y.; Liu, A.; Xiao, J.; Zhu, Y.
Ectopic expression of a Glycine soja myo-inositol oxygenase gene (GsMIOX1a) in Arabidopsis enhances tolerance to alkaline stress
PLoS ONE
10
e0129998
2015
Arabidopsis thaliana (Q8L799), Glycine soja (A0A0B2PCG9), Glycine soja, Glycine soja 07256 (A0A0B2PCG9)
Sharma, I.; Dutta, R.K.; Singh, N.K.; Kanwar, Y.S.
High glucose-induced hypomethylation promotes binding of Sp-1 to myo-inositol oxygenase implication in the pathobiology of diabetic tubulopathy
Am. J. Pathol.
187
724-739
2017
Homo sapiens, Mus musculus (Q9QXN5), Mus musculus
Tominaga, T.; Sharma, I.; Fujita, Y.; Doi, T.; Wallner, A.K.; Kanwar, Y.S.
Myo-inositol oxygenase accentuates renal tubular injury initiated by endoplasmic reticulum stress
Am. J. Physiol. Renal Physiol.
316
F301-F315
2019
Homo sapiens, Sus scrofa, Mus musculus (Q9QXN5)
Alok, A.; Kaur, J.; Tiwari, S.
Functional characterization of wheat myo-inositol oxygenase promoter under different abiotic stress conditions in Arabidopsis thaliana
Biotechnol. Lett.
42
2035-2047
2020
Triticum aestivum
Teng, F.; You, R.; Hu, M.; Liu, W.; Wang, L.; Tao, Y.
Production of D-glucuronic acid from myo-inositol using Escherichia coli whole-cell biocatalyst overexpressing a novel myo-inositol oxygenase from Thermothelomyces thermophile
Enzyme Microb. Technol.
127
70-74
2019
Arabidopsis thaliana (A0A178V136), Arabidopsis thaliana, Thermothelomyces thermophilus (G2QA66), Thermothelomyces thermophilus, Mus musculus (Q9QXN5), Mus musculus, Thermothelomyces thermophilus ATCC 42464 (G2QA66)
Dutta, R.K.; Kondeti, V.K.; Sharma, I.; Chandel, N.S.; Quaggin, S.E.; Kanwar, Y.S.
Beneficial effects of myo-inositol oxygenase deficiency in cisplatin-induced AKI
J. Am. Soc. Nephrol.
28
1421-1436.
2017
Mus musculus (Q9QXN5)
Deng, F.; Sharma, I.; Dai, Y.; Yang, M.; Kanwar, Y.S.
Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule
J. Clin. Invest.
129
5033-5049
2019
Homo sapiens
Mertoglu, C.; Gunay, M.; Gurel, A.; Gungor, M.
Myo-inositol oxygenase as a novel marker in the diagnosis of acute kidney injury
J. Med. Biochem.
37
1-6.
2018
Homo sapiens
Zheng, S.; Hou, J.; Zhou, Y.; Fang, H.; Wang, T.T.; Liu, F.; Wang, F.S.; Sheng, J.Z.
One-pot two-strain system based on glucaric acid biosensor for rapid screening of myo-inositol oxygenase mutations and glucaric acid production in recombinant cells
Metab. Eng.
49
212-219
2018
Mus musculus (Q9QXN5)
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